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Results: 279
Discovering Serendipity
Dengue is the most rapidly spreading mosquito-borne viral disease in the world, with an annual incidence of over 100 million infections (Malavige, 2006).
The disease is caused by four distinct, but closely related, virus...
Published by: Cambridge Medicine Journal
Social Media in Business Decisions of MSMEs
Social media has progressively grown in the last century and is now seen as a potential opportunity for various purposes, including the decision-making. The present work explores how social media platforms such as Facebook...
Published by: IGI Global Scientific Publishing
A Genetic Algorithm-Based Neuro-Fuzzy Controller for Unmanned Aerial Vehicle Control
In this paper a self-tuning Adaptive Neuro-fuzzy Inference System (ANFIS) Controller by Genetic Algorithm (GA) applied to trajectory tracking task of Unmanned Aerial Vehicle (UAV) is studied. The quadrotor was chosen due to its...
Published by: IGI Global Scientific Publishing
Does a regular Wessex Head Injury Matrix assessment identify early signs of infections in people with Prolonged Disorders of Consciousness?
Samira Kashinath Dhamapurkar, Barbara A Wilson, Anita Rose, Gerhard Florschutz, Peter Watson, Agnes Shiel
Jan 31, 2019
BACKGROUND & OBJECTIVE: Patients with brain injury are at high risk for infections. Although infection and cognitive deterioration are established for people with dementia, this has not been shown for patients with a prolonged...
Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development.
The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination.
Annie Pu, Manoj K Mishra, Yifei Dong, Samira Ghorbanigazar, Erin L Stephenson, Khalil S Rawji, Claudia Silva, Hiroshi Kitagawa, Stephen Sawcer, V Wee Yong
Jul 15, 2020
CSPG Demyelination EXTL2 Inflammation Multiple Sclerosis oligodendrocyte Animals Chondroitin Sulfate Proteoglycans Demyelinating Diseases Female Humans Inflammation MACROPHAGES Male Membrane Proteins Mice Mice Inbred C57BL Mice Knockout Multiple Sclerosis N-Acetylglucosaminyltransferases Polymorphism Single Nucleotide
A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.
Cécile Rouzier, David Moore, Cécile Delorme, Sandra Lacas-Gervais, Samira Ait-El-Mkadem, Konstantina Fragaki, Florence Burté, Valérie Serre, Sylvie Bannwarth, Annabelle Chaussenot, Martin Catala, Patrick Yu-Wai-Man, Véronique Paquis-Flucklinger
Jun 28, 2018
Wolfram syndrome (WS) is a progressive neurodegenerative disease characterized by early-onset optic atrophy and diabetes mellitus, which can be associated with more extensive central nervous system and endocrine complications....
A New Design of a Functional H Filter for Linear Singular Systems With an Additional Unknown Input and Bounded Disturbances
This paper proposes a design of a H_¥ filter for a functional of the system state that the authors call functional H_¥ filter in time domain for linear singular systems with additional unknown inputs and bounded disturbances....
Published by: IGI Global Scientific Publishing
Design of a Functional H Filter for Linear Singular Systems With an Additional Unknown Input, Bounded Disturbance, and Variable Time Delay
This paper deals with a new method for the design of a functional filter for linear singular systems with bounded disturbance and variable time delay in the state and the known input vectors. Moreover, a disturbance unknown...
Published by: IGI Global Scientific Publishing
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians.
Yang Luo, Sara Suliman, Samira Asgari, Tiffany Amariuta, Yuriy Baglaenko, Marta Martínez-Bonet, Kazuyoshi Ishigaki, Maria Gutierrez-Arcelus, Roger Calderon, Leonid Lecca, Segundo R León, Judith Jimenez, Rosa Yataco, Carmen Contreras, Jerome T Galea, Mercedes Becerra, Sergey Nejentsev, Peter A Nigrovic, D Branch Moody, Megan B Murray, Soumya Raychaudhuri
Oct 22, 2019
Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5-15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection, presumably...
Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.
Nigel I Wood, Valentina Carta, Stefan Milde, Elizabeth A Skillings, Catherine J McAllister, YL Mabel Ang, Alasdair Duguid, Nadeev Wijesuriya, Samira Mohd Afzal, Joe X Fernandes, TW Leong, A Jennifer Morton
Feb 13, 2020
BACKGROUND: Environmental enrichment (EE) in laboratory animals improves neurological function and motor/cognitive performance, and is proposed as a strategy for treating neurodegenerative diseases. EE has been investigated in...
Differential interaction with TREM2 modulates microglial uptake of modified Aβ species.
Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia.
Andrew E Armitage, Pei Jin Lim, Joe N Frost, Sant-Rayn Pasricha, Elizabeth J Soilleux, Emma Evans, Alireza Morovat, Ana Santos, Rebeca Diaz, Daniel Biggs, Benjamin Davies, Uzi Gileadi, Peter A Robbins, Samira Lakhal-Littleton, Hal Drakesmith
Dec 20, 2019
Withdrawal of iron from serum (hypoferraemia) is a conserved innate immune antimicrobial strategy that can withhold this critical nutrient from invading pathogens, impairing their growth. Hepcidin (Hamp1) is the master regulator...
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians
Yang Luo, Sara Suliman, Samira Asgari, Tiffany Amariuta, Yuriy Baglaenko, Marta Martínez-Bonet, Kazuyoshi Ishigaki, Maria Gutierrez-Arcelus, Roger Calderon, Leonid Lecca, Segundo R. León, Judith Jimenez, Rosa Yataco, Carmen Contreras, Jerome T. Galea, Mercedes Becerra, Sergey Nejentsev, Peter A. Nigrovic, D. Branch Moody, Megan B. Murray, Soumya Raychaudhuri
Aug 20, 2020
Abstract: Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5–15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection...
Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes.
Marco Colombo, Stuart J McGurnaghan, Luke AK Blackbourn, R Neil Dalton, David Dunger, Samira Bell, John R Petrie, Fiona Green, Sandra MacRury, John A McKnight, John Chalmers, Andrew Collier, Paul M McKeigue, Helen M Colhoun, Scottish Diabetes Research Network (SDRN) Type 1 Bioresource Investigators
Jan 07, 2021
AIMS/HYPOTHESIS: We examined whether candidate biomarkers in serum or urine can improve the prediction of renal disease progression in type 1 diabetes beyond prior eGFR, comparing their performance with urinary...
Clinical science EPIDEMIOLOGY Metabolomics Nephropathy Proteomics Adult Aged Albumins Albuminuria Biomarkers Blood Chemical Analysis Cohort Studies Creatinine Diabetes mellitus Type 1 Diabetic Nephropathies Diagnostic Techniques Endocrine Enzyme-Linked Immunosorbent Assay Female Humans Kidney Function Tests Male Middle Aged Prognosis Prospective Studies Scotland Serum Albumin Urinalysis
Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes
Marco Colombo, Stuart J. McGurnaghan, Luke A. K. Blackbourn, R. Neil Dalton, David Dunger, Samira Bell, John R. Petrie, Fiona Green, Sandra MacRury, John A. McKnight, John Chalmers, Andrew Collier, Paul M. McKeigue, Helen M. Colhoun
Jun 06, 2020
Abstract: Aims/hypothesis: We examined whether candidate biomarkers in serum or urine can improve the prediction of renal disease progression in type 1 diabetes beyond prior eGFR, comparing their performance with urinary...
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Sylvie Bannwarth, Samira Ait-El-Mkadem, Annabelle Chaussenot, Emmanuelle C Genin, Sandra Lacas-Gervais, Konstantina Fragaki, Laetitia Berg-Alonso, Yusuke Kageyama, Valérie Serre, David G Moore, Annie Verschueren, Cécile Rouzier, Isabelle Le Ber, Gaëlle Augé, Charlotte Cochaud, Françoise Lespinasse, Karine N'Guyen, Anne de Septenville, Alexis Brice, Patrick Yu-Wai-Man, Hiromi Sesaki, Jean Pouget, Véronique Paquis-Flucklinger
Mar 18, 2019
Mitochondrial DNA instability disorders are responsible for a large clinical spectrum, among which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are extremely rare. We report a large family with a...
CHCHD10 FTD-ALS mitochondrial DNA instability mitochondrial disorder Age of Onset Aged Alleles Amyotrophic Lateral Sclerosis DNA Mitochondrial Exome Female frontotemporal dementia HeLa Cells Humans Male Middle Aged Mitochondria Mitochondrial Diseases Mitochondrial Proteins Mutation Missense Pedigree Phenotype
Artificial intelligence in nursing
Charlene Esteban Ronquillo, Laura-Maria Peltonen, Lisiane Pruinelli, Charlene H Chu, Suzanne Bakken, Ana Beduschi, Kenrick Cato, Nicholas Hardiker, Alain Junger, Martin Michalowski, Rune Nyrup, Samira Rahimi, Donald Nigel Reed, Tapio Salakoski, Sanna Salanterä, Nancy Walton, Patrick Weber, Thomas Wiegand, Maxim Topaz
Mar 23, 2021
Sustainability of bioenergy – Mapping the risks & benefits to inform future bioenergy systems
Andrew James Welfle, Alberto Almena, Muhammad Naveed Arshad, Scott William Banks, Isabela Butnar, Katie Jane Chong, Samuel J. G. Cooper, Helen Daly, Samira Garcia Freites, Fatih Güleç, Christopher Hardacre, Robert Holland, Lan Lan, Chai Siah Lee, Peter Robertson, Rebecca Rowe, Anita Shepherd, Nathan Skillen, Silvia Tedesco, Patricia Thornley, Pedro Verdía Barbara, Ian Watson, Orla Sioned Aine Williams, Mirjam Roder
Oct 31, 2023
Bioenergy is widely included in energy strategies for its GHG mitigation potential. Bioenergy technologies will likely have to be deployed at scale to meet decarbonisation targets, and consequently biomass will have to be...
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Yahong Guo, Nataliya Nady, Chao Qi, Abdellah Allali-Hassani, Haizhong Zhu, Patricia Pan, Melanie A Adams-Cioaba, Maria F Amaya, Aiping Dong, Masoud Vedadi, Matthieu Schapira, Randy J Read, Cheryl H Arrowsmith, Jinrong Min
May 11, 2020
The MBT repeat has been recently identified as a key domain capable of methyl-lysine histone recognition. Functional work has pointed to a role for MBT domain-containing proteins in transcriptional repression of developmental...
PHI-base
Martin Urban, Alayne Cuzick, James Seager, Valerie Wood, Kim Rutherford, Shilpa Yagwakote Venkatesh, Nishadi De Silva, Manuel Carbajo Martinez, Helder Pedro, Andy D Yates, Keywan Hassani-Pak, Kim E Hammond-Kosack
Oct 11, 2019
The pathogen-host interactions database (PHI-base) is available at www.phi-base.org. PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions...
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