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Differential interaction with TREM2 modulates microglial uptake of modified Aβ species.

Pranav Joshi, Florian Riffel, Kanayo Satoh, Masahiro Enomoto, Seema Qamar, Hannah Scheiblich, Nàdia Villacampa, Sathish Kumar, Sandra Theil, Samira Parhizkar, Christian Haass, Michael T Heneka, Paul E Fraser, Peter St George-Hyslop, Jochen Walter

OAI: oai:www.repository.cam.ac.uk:1810/327213 • DOI: 10.17863/CAM.74662

Abstract

Alzheimer's Disease FTD mutation TREM2 amyloid β Phosphorylation post-translational modification Alzheimer Disease Amyloid beta-Peptides Amyloid beta-Protein Precursor Animals Disease Models Animal Membrane Glycoproteins Mice Mice Transgenic Microglia Receptors Immunologic