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Results: 335
Role of Laminin gamma 1 in Cortical Development
Veronique Haegeli
Jan 01, 0001
Laminins are a major component of basement membranes, including those in the central nervous system (CNS). To explore the role of laminin \l, a subunit common to all laminins found within the CNS, we developed a murine model in...
Published by: Rockefeller University
A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
Claudio Raimondi, Veronique Calleja, Riccardo Ferro, Alessandro Fantin, Andrew M Riley, Barry V L Potter, Caroline H Brennan, Tania Maffucci, Banafshé Larijani, Marco Falasca
May 20, 2016
Strong evidence suggests that Phospholipase Cγ1 (PLCγ1) is a suitable target to counteract tumourigenesis and metastasis dissemination. We recently identified a novel signalling pathway required for PLCγ1 activation which...
Longitudinal genomic surveillance of multidrug-resistant Escherichia coli carriage in a long-term care facility in the United Kingdom.
Hayley J Brodrick, Kathy E Raven, Teemu Kallonen, Dorota Jamrozy, Beth Blane, Nicholas M Brown, Veronique Martin, M Estée Török, Julian Parkhill, Sharon J Peacock
Jul 25, 2017
BACKGROUND: Residents of long-term care facilities (LTCF) may have high carriage rates of multidrug-resistant pathogens, but are not currently included in surveillance programmes for antimicrobial resistance or...
Establishing population-based surveillance of diagnostic timeliness using linked cancer registry and administrative data for patients with colorectal and lung cancer.
Longitudinal genomic surveillance of multidrug-resistant Escherichia coli carriage in a long-term care facility in the United Kingdom.
Hayley J Brodrick, Kathy E Raven, Teemu Kallonen, Dorota Jamrozy, Beth Blane, Nicholas M Brown, Veronique Martin, M Estée Török, Julian Parkhill, Sharon Peacock
Jun 26, 2018
Humans Escherichia coli Escherichia coli Infections beta-Lactamases Escherichia coli Proteins Long-Term Care Sequence Analysis DNA Drug Resistance Multiple Bacterial United Kingdom
Published by: Genome medicine
A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
Claudio Raimondi, Veronique Calleja, Riccardo Ferro, Alessandro Fantin, Andrew M Riley, Barry V L Potter, Caroline H Brennan, Tania Maffucci, Banafshé Larijani, Marco Falasca
May 20, 2016
Strong evidence suggests that Phospholipase Cγ1 (PLCγ1) is a suitable target to counteract tumourigenesis and metastasis dissemination. We recently identified a novel signalling pathway required for PLCγ1 activation which...
A three-dimensional atlas of human dermal leukocytes, lymphatics, and blood vessels.
Xiao-Nong Wang, Naomi McGovern, Merry Gunawan, Connor Richardson, Martin Windebank, Tee-Wei Siah, Hwee-Ying Lim, Katja Fink, Jackson L Yao Li, Lai G Ng, Florent Ginhoux, Veronique Angeli, Matthew Collin, Muzlifah Haniffa
Jun 29, 2018
Dendritic cells (DCs), macrophages (Mφ), and T cells are major components of the skin immune system, but their interstitial spatial organization is poorly characterized. Using four-channel whole-mount immunofluorescence staining...
Adolescent Adult Aged ANISOTROPY CD11c Antigen Carrier Proteins Cell Movement Dermis Female Flow Cytometry Humans Langerhans Cells Leukocytes Lymphatic System Lymphatic Vessels Lymphocytes Lymphoma T-Cell Cutaneous MACROPHAGES Microfilament Proteins Middle Aged Phenotype Platelet Endothelial Cell Adhesion Molecule-1 Skin Young Adult
Synchrotron cooling in energetic gamma-ray bursts observed by the <i>Fermi</i> Gamma-Ray Burst Monitor
Hoi Fung Yu, Jochen Greiner, Hendrik Van Eerten, J. Michael Burgess, P. Narayana Bhat, Michael S. Briggs, Valerie Connaughton, Roland Diehl, Adam Goldstein, David Gruber, Peter A. Jenke, Andreas von Kienlin, Chryssa Kouveliotou, William S. Paciesas, Veronique Pelassa, Robert D. Preece, Oliver J. Roberts, Bin-Bin Zhang
Jan 01, 2015
Context. We study the time-resolved spectral properties of energetic gamma-ray bursts (GRBs) with good high-energy photon statistics observed by the Gamma-Ray Burst Monitor (GBM) onboard the Fermi Gamma-Ray Space Telescope....
International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease.
Pablo A Olivera, Stephane Zuily, Paulo G Kotze, Veronique Regnault, Sameer Al Awadhi, Peter Bossuyt, Richard B Gearry, Subrata Ghosh, Taku Kobayashi, Patrick Lacolley, Edouard Louis, Fernando Magro, Siew C Ng, Alfredo Papa, Tim Raine, Fabio V Teixeira, David T Rubin, Silvio Danese, Laurent Peyrin-Biroulet
Sep 28, 2021
Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based Guideline were to summarize available...
Published by: Nature reviews. Gastroenterology & hepatology
Primary post-transplant lymphoproliferative disorder of the central nervous system
Mary M Taj, Britta Maecker-Kolhoff, Rebecca Ling, Simon Bomken, Birgit Burkhardt, Alan KS Chiang, Monika Csoka, Anna Füreder, Stéphanie Haouy, Jelena Lazic, Natalia Miakova, Veronique Minard-Colin, Suzanne D Turner, Anne Uyttebroeck, Andishe Attarbaschi, the international Berlin-Frankfurt-Münster (i-BFM) Study Group European Intergroup for Childhood Non-Hodgkin’s Lymphoma (EICNHL)
Feb 17, 2021
Primary central nervous system (CNS) post-transplant lymphoproliferative disorder (PTLD) in childhood is rare. Twenty-five patients were retrieved from nine European Intergroup for Childhood Non-Hodgkin's Lymphoma and/or...
Central Nervous System outcome post-transplant lymphoproliferative disorder transplant Treatment Adolescent Adult Allografts Brain Neoplasms Child Child Preschool Disease-Free Survival Female Hematopoietic Stem Cell Transplantation Humans Infant Injections Spinal Lymphoproliferative Disorders Male Organ Transplantation Rituximab Survival Rate
A systematic review of antibody mediated immunity to coronaviruses
Angkana T. Huang, Bernardo Garcia-Carreras, Matt D. T. Hitchings, Bingyi Yang, Leah C. Katzelnick, Susan M. Rattigan, Brooke A. Borgert, Carlos A. Moreno, Benjamin D. Solomon, Luke Trimmer-Smith, Veronique Etienne, Isabel Rodriguez-Barraquer, Justin Lessler, Henrik Salje, Donald S. Burke, Amy Wesolowski, Derek A. T. Cummings
Sep 17, 2020
A systematic review of antibody mediated immunity to coronaviruses
Angkana T. Huang, Bernardo Garcia-Carreras, Matt D. T. Hitchings, Bingyi Yang, Leah C. Katzelnick, Susan M. Rattigan, Brooke A. Borgert, Carlos A. Moreno, Benjamin D. Solomon, Luke Trimmer-Smith, Veronique Etienne, Isabel Rodriguez-Barraquer, Justin Lessler, Henrik Salje, Donald S. Burke, Amy Wesolowski, Derek A. T. Cummings
Sep 17, 2021
Research priorities for neuroimmunology
Georgina MacKenzie, Sumithra Subramaniam, Lindsey J Caldwell, Denise Fitzgerald, Neil A Harrison, Soyon Hong, Sarosh R Irani, Golam M Khandaker, Adrian Liston, Veronique E Miron, Valeria Mondelli, B Paul Morgan, Carmine Pariante, Divya K Shah, Leonie S Taams, Jessica L Teeling, Rachel Upthegrove
Jan 07, 2022
Neuroimmunology in the broadest sense is the study of interactions between the nervous and the immune systems. These interactions play important roles in health from supporting neural development, homeostasis and plasticity to...
A systematic review of antibody mediated immunity to coronaviruses
Angkana T Huang, Bernardo Garcia-Carreras, Matt DT Hitchings, Bingyi Yang, Leah C Katzelnick, Susan M Rattigan, Brooke A Borgert, Carlos A Moreno, Benjamin D Solomon, Luke Trimmer-Smith, Veronique Etienne, Isabel Rodriguez-Barraquer, Justin Lessler, Henrik Salje, Donald S Burke, Amy Wesolowski, Derek AT Cummings
Nov 05, 2020
Many public health responses and modeled scenarios for COVID-19 outbreaks caused by SARS-CoV-2 assume that infection results in an immune response that protects individuals from future infections or illness for some amount of...
Synchrotron cooling in energetic gamma-ray bursts observed by the <i>Fermi</i> Gamma-Ray Burst Monitor
Hoi Fung Yu, Jochen Greiner, Hendrik Van Eerten, J. Michael Burgess, P. Narayana Bhat, Michael S. Briggs, Valerie Connaughton, Roland Diehl, Adam Goldstein, David Gruber, Peter A. Jenke, Andreas von Kienlin, Chryssa Kouveliotou, William S. Paciesas, Veronique Pelassa, Robert D. Preece, Oliver J. Roberts, Bin-Bin Zhang
Jan 01, 2015
Context. We study the time-resolved spectral properties of energetic gamma-ray bursts (GRBs) with good high-energy photon statistics observed by the Gamma-Ray Burst Monitor (GBM) onboard the Fermi Gamma-Ray Space Telescope....
International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease.
Pablo A Olivera, Stephane Zuily, Paulo G Kotze, Veronique Regnault, Sameer Al Awadhi, Peter Bossuyt, Richard B Gearry, Subrata Ghosh, Taku Kobayashi, Patrick Lacolley, Edouard Louis, Fernando Magro, Siew C Ng, Alfredo Papa, Tim Raine, Fabio V Teixeira, David T Rubin, Silvio Danese, Laurent Peyrin-Biroulet
Nov 24, 2021
Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based Guideline were to summarize available...
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
Juliette Van Steenwinckel, Anne-Laure Schang, Michelle L Krishnan, Vincent Degos, Andrée Delahaye-Duriez, Cindy Bokobza, Zsolt Csaba, Franck Verdonk, Amélie Montané, Stéphanie Sigaut, Olivier Hennebert, Sophie Lebon, Leslie Schwendimann, Tifenn Le Charpentier, Rahma Hassan-Abdi, Gareth Ball, Paul Aljabar, Alka Saxena, Rebecca K Holloway, Walter Birchmeier, Olivier Baud, David Rowitch, Veronique Miron, Fabrice Chretien, Claire Leconte, Valérie C Besson, Enrico G Petretto, A David Edwards, Henrik Hagberg, Nadia Soussi-Yanicostas, Bobbi Fleiss, Pierre Gressens
Jan 31, 2020
Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors.
Marjorie Poggi, Matthias Canault, Marie Favier, Ernest Turro, Paul Saultier, Dorsaf Ghalloussi, Veronique Baccini, Lea Vidal, Anna Mezzapesa, Nadjim Chelghoum, Badreddine Mohand-Oumoussa, Céline Falaise, Rémi Favier, Willem H Ouwehand, Mathieu Fiore, Franck Peiretti, Pierre Emmanuel Morange, Noémie Saut, Denis Bernot, Andreas Greinacher, Nihr BioResource, Alan T Nurden, Paquita Nurden, Kathleen Freson, David-Alexandre Trégouët, Hana Raslova, Marie-Christine Alessi
May 31, 2018
Variants in ETV6, which encodes a transcription repressor of the E26 transformation-specific family, have recently been reported to be responsible for inherited thrombocytopenia and hematologic malignancy. We sequenced the DNA...
Antigens CD34 Blood Cell Count Blood Platelets Cell Differentiation Family Female Gene Expression Regulation Genotype Germ-Line Mutation Hematopoietic Stem Cells Humans Hyperplasia Male Megakaryocytes Pedigree Phenotype Platelet Count Proto-Oncogene Proteins c-ets Repressor Proteins Thrombopoiesis Transcription Genetic
Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.
Stephanie Z Xie, Laura Garcia-Prat, Veronique Voisin, Robin Ferrari, Olga I Gan, Elvin Wagenblast, Kerstin B Kaufmann, Andy GX Zeng, Shin-Ichiro Takayanagi, Ishita Patel, Esther K Lee, Joseph Jargstorf, Gareth Holmes, Guy Romm, Kristele Pan, Michelle Shoong, Aditi Vedi, Chiara Luberto, Mark D Minden, Gary D Bader, Elisa Laurenti, John E Dick
Sep 26, 2019
DEGS1 StemRegenin-1 UM171 Autophagy Fenretinide Hematopoietic stem cell lipidomics sphingolipid metabolism umbilical cord blood Unfolded Protein Response Animals Autophagy Cell Differentiation Cell Self Renewal Cell Survival Endoplasmic reticulum stress Fatty Acid Desaturases Female Fenretinide Gene Expression Regulation Gene Knockdown Techniques Hematopoietic Stem Cells Humans Male Mass Spectrometry Mice Mice Inbred NOD Proteostasis RNA Small Interfering RNA-seq Single-Cell Analysis sphingolipids Transplantation Heterologous
Treatment and Outcome Analysis of 639 Relapsed Non-Hodgkin Lymphomas in Children and Adolescents and Resulting Treatment Recommendations.
Birgit Burkhardt, Mary Taj, Nathalie Garnier, Veronique Minard-Colin, Volkan Hazar, Karin Mellgren, Tomoo Osumi, Alina Fedorova, Natalia Myakova, Jaime Verdu-Amoros, Mara Andres, Edita Kabickova, Andishe Attarbaschi, Alan Kwok Shing Chiang, Eva Bubanska, Svetlana Donska, Lisa Lyngsie Hjalgrim, Jacek Wachowiak, Anna Pieczonka, Anne Uyttebroeck, Jelena Lazic, Jan Loeffen, Jochen Buechner, Felix Niggli, Monika Csoka, Gergely Krivan, Julia Palma, GA Amos Burke, Auke Beishuizen, Kristin Koeppen, Stephanie Mueller, Heidi Herbrueggen, Wilhelm Woessmann, Martin Zimmermann, Adriana Balduzzi, Marta Pillon
Apr 26, 2021
Despite poor survival, controversies remain in the treatment for refractory or relapsed pediatric non-Hodgkin lymphoma (r/r NHL). The current project aimed to collect international experience on the re-induction treatment of r/r...
European consensus statement on diagnosis and treatment of adult ADHD
Sandra JJ Kooij, Susanne Bejerot, Andrew Blackwell, Herve Caci, Miquel Casas-Brugué, Pieter J Carpentier, Dan Edvinsson, John Fayyad, Karin Foeken, Michael Fitzgerald, Veronique Gaillac, Ylva Ginsberg, Chantal Henry, Johanna Krause, Michael B Lensing, Iris Manor, Helmut Niederhofer, Carlos Nunes-Filipe, Martin D Ohlmeier, Pierre Oswald, Stefano Pallanti, Artemios Pehlivanidis, Josep A Ramos-Quiroga, Maria Rastam, Doris Ryffel-Rawak, Steven Stes, Philip Asherson
Aug 20, 2020
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that persists into adulthood in the majority of cases. The evidence on persistence poses several...
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