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Results: 12958
The first spectroscopic IR reverberation programme on Mrk 509
J A J Mitchell, M. J. Ward, D. Kynoch, J V Hernández Santisteban, Keith Horne, J.-U. Pott, J. Esser, P Mercatoris, C Packham, G.~J. Ferland, A Lawrence, T Fischer, A.J. Barth, Carolin Villforth, H. Winkler
Apr 10, 2024
Near IR spectroscopic reverberation of Active Galactic Nuclei (AGN) potentially allows the infrared (IR) broad line region (BLR) to be reverberated alongside the disc and dust continua, while the spectra can also reveal...
The Role of Science Institutions in Our Civilization
This booklet prints the Founders' Day address delivered by Dr. William D. Coolidge at Ursinus College on October 13, 1942, as well as a speech by Dr. George E. Pfahler and others.
Published by: Ursinus College
Progression of Neuropsychiatric Symptoms over Time in an Incident Parkinson’s Disease Cohort (ICICLE-PD)
J. K. Dlay, G. W. Duncan, T. K. Khoo, C. H. Williams-Gray, D. P. Breen, R. A. Barker, D. J. Burn, R. A. Lawson, A. J. Yarnall
Feb 03, 2020
Background: Cross-sectional studies have identified that the prevalence of neuropsychiatric symptoms (NPS) in Parkinson’s disease (PD) ranges from 70−89%. However, there are few longitudinal studies determining the impact of NPS...
Selective electrochemiluminescent sensing of saccharides using boronic acid-modified coreactant
Haidong Li, Adam C. Sedgwick, Meng Li, Richard A R Blackburn, Steven D. Bull, Stéphane Arbault, Tony D. James, Neso Sojic
Nov 11, 2016
We report a strategy for modulating the electrogenerated chemiluminescence (ECL) response by integrating a boronic acid to the chemical structure of coreactants. Excellent selectivity for d-glucose was achieved by tuning the...
Selective electrochemiluminescent sensing of saccharides using boronic acid-modified coreactant
Haidong Li, Adam C. Sedgwick, Meng Li, Richard A R Blackburn, Steven D. Bull, Stéphane Arbault, Tony D. James, Neso Sojic
Nov 11, 2016
We report a strategy for modulating the electrogenerated chemiluminescence (ECL) response by integrating a boronic acid to the chemical structure of coreactants. Excellent selectivity for d-glucose was achieved by tuning the...
Impact of alloy fluctuations and Coulomb effects on the electronic and optical properties of c-plane GaN/AlGaN quantum wells.
A A Roble, S K Patra, F Massabuau, M Frentrup, M A Leontiadou, P Dawson, M J Kappers, R A Oliver, D M Graham, S Schulz
Jan 12, 2020
We report on a combined theoretical and experimental study of the impact of alloy fluctuations and Coulomb effects on the electronic and optical properties of [Formula: see text]-plane GaN/AlGaN multi-quantum well systems. The...
Halide perovskites scintillators
The widespread use of X- and gamma-rays in a range of sectors including healthcare, security and industrial screening is underpinned by the efficient detection of the ionising radiation. Such detector applications are dominated...
The application of an age adjusted D-dimer threshold to rule out suspected venous thromboembolism (VTE) in an emergency department setting
BACKGROUND: Venous Thromboembolic disease (VTE) poses a diagnostic challenge for clinicians in acute care. Over reliance on reference standard investigations can lead to over treatment and potential harm. We sought to evaluate...
N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.
Adrian J Butcher, Ignacio Torrecilla, Kenneth W Young, Kok Choi Kong, Sharad C Mistry, Andrew R Bottrill, Andrew B Tobin
Aug 20, 2020
Changes in synaptic strength mediated by ionotropic glutamate N-methyl-D-asparate (NMDA) receptors is generally considered to be the molecular mechanism underlying memory and learning. NMDA receptors themselves are subject to...
Amino Acid Sequence Animals Calcium Signaling Calcium-Calmodulin-Dependent Protein Kinase Type 2 Cells Cultured cerebellum Feedback Physiological Mice Mice Knockout Molecular Sequence Data N-Methylaspartate Neuronal Plasticity Neurons Phosphatidylinositols Phosphorylation Receptor Muscarinic M3 Receptors N-Methyl-D-Aspartate Recombinant Fusion Proteins Signal Transduction
Evaluation of Thrombocytopenia and Its Inter-Relationship with Hematological Parameters in Malaria.
Background: Malaria is a disease known since the middle ages and despite huge progress in medical sciences still remains a cause of significant number of deaths annually.The key to limiting morbidity and mortality in malaria is...
Published by: IJHS Medical Association
Evaluation of Thrombocytopenia and Its Inter-Relationship with Hematological Parameters in Malaria.
Background: Malaria is a disease known since the middle ages and despite huge progress in medical sciences still remains a cause of significant number of deaths annually.The key to limiting morbidity and mortality in malaria is...
Published by: IJHS Medical Association
Rhinoscleroma Revisited
Rhinoscleroma is a chronic disease characterized by the formation of granuloma in the airways, caused by the bacterium Klebsiella pneumoniae subspecies rhinoscleromatis. It was earlier thought to involve only nasal passages but...
Published by: IJHS Medical Association
The recognition of collagen and triple-helical toolkit peptides by MMP-13
Joanna-Marie Howes, Dominique Bihan, David A Slatter, Samir W Hamaia, Len C Packman, Vera Knauper, Robert Visse, Richard W Farndale
Jul 17, 2014
Collagen Collagenolysis Hemopexin Domain MMP-13 Matrix Metalloproteinase (MMP) Protease Protein Conformation Substrate Specificity Toolkit Peptides Amino Acid Sequence Base Sequence Collagen Type II DNA Primers Matrix Metalloproteinase 13 Molecular Sequence Data Peptides Proteolysis Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Substrate Specificity
A structure determination protocol based on combined analysis of 3D-ED data, powder XRD data, solid-state NMR data and DFT-D calculations reveals the structure of a new polymorph of L-tyrosine
Christopher Smalley, Harriet Hoskynes, Colan Hughes, Duncan Johnstone, Tom Willhammer, Mark Young, Christopher Pickard, Andrew Logsdail, Paul Midgley, Kenneth Harris
Jul 03, 2022
We report the crystal structure of a new polymorph of L-tyrosine (denoted the β polymorph), prepared by crystallization from the gas phase following vacuum sublimation. Structure determination was carried out by combined...
Thresholds of physical activity associated with obesity by level of sedentary behaviour in children
J-P Chaput, J D Barnes, M S Tremblay, M Fogelholm, G Hu, E V Lambert, C Maher, J Maia, T Olds, V Onywera, O L Sarmiento, M Standage, C Tudor-Locke, P T Katzmarzyk
Jul 01, 2018
BACKGROUND: It is unknown whether moderate-to-vigorous physical activity (MVPA) thresholds for obesity should be adapted depending on level of sedentary behaviour in children.
OBJECTIVE: The objective of the study is to...
Impact of alloy fluctuations and Coulomb effects on the electronic and optical properties of c -plane GaN/AlGaN quantum wells
A. A. Roble, S. K. Patra, F. Massabuau, M. Frentrup, M. A. Leontiadou, P. Dawson, M. J. Kappers, R. A. Oliver, D. M. Graham, S. Schulz
Dec 10, 2020
Abstract: We report on a combined theoretical and experimental study of the impact of alloy fluctuations and Coulomb effects on the electronic and optical properties of c-plane GaN/AlGaN multi-quantum well systems. The presence...
Using pulsed mode scanning electron microscopy for cathodoluminescence studies on hybrid perovskite films
Jordi Ferrer Orri, Elizabeth M Tennyson, Gunnar Kusch, Giorgio Divitini, Stuart Macpherson, Rachel A Oliver, Caterina Ducati, Samuel D Stranks
May 20, 2021
Abstract: The use of pulsed mode scanning electron microscopy cathodoluminescence (CL) for both hyperspectral mapping and time-resolved measurements is found to be useful for the study of hybrid perovskite films, a class of...
Effect of Micron-scale Photoluminescence Variation on Droop Measurements in InGaN/GaN Quantum Wells
R M Barrett, R Ahumada-Lazo, J A Alanis, P Parkinson, S A Church, M J Kappers, R A Oliver, D J Binks
Jul 01, 2021
Abstract: Micro-photoluminescence maps reveal micron-scale spatial variation in intensity, peak emission energy and bandwidth across InGaN/GaN quantum wells. To investigate the effect of this spatial variation on measurements of...
Acute regional changes in myocardial strain may predict ventricular remodelling after myocardial infarction in a large animal model.
DS Mansell, VD Bruno, E Sammut, A Chiribiri, T Johnson, I Khaliulin, D Baz Lopez, HS Gill, KH Fraser, M Murphy, T Krieg, MS Suleiman, S George, R Ascione, AN Cookson
Oct 08, 2021
To identify predictors of left ventricular remodelling (LVR) post-myocardial infarction (MI) and related molecular signatures, a porcine model of closed-chest balloon MI was used along with serial cardiac magnetic resonance...
Animals Biomarkers Computational Biology Data analysis Data Interpretation Statistical Disease Models Animal Disease Susceptibility Female Image Processing Computer-Assisted Magnetic Resonance Imaging Myocardial Infarction Myocardium Proteome Proteomics Reproducibility of Results Swine Translational Research Biomedical Ventricular Function Left Ventricular Remodeling
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