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Results: 293
Small bowel Gastrointestinal Stromal Tumors can physiologically alter gut motility before causing mechanical obstruction.
BACKGROUND: Gastro Intestinal Stromal Tumors (GISTs) are rare stromal neoplasms that represent the most common mesenchymal tumor of the G.I. tract, accounting for 5% of all sarcomas. Originating from interstitial cells of Cajal...
Assessment of human leukocyte antigen immunogenicity
PURPOSE OF REVIEW: Donor-recipient human leukocyte antigen (HLA) matching improves outcomes after solid-organ transplantation, but current assessment of HLA incompatibility is inadequate as it does not consider the relative...
Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level
Development of adaptive immunity after COVID-19 and after vaccination against SARS-CoV-2 is predicated on recognition of viral peptides, presented on HLA class II molecules, by CD4+ T-cells. We capitalised on extensive...
Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level.
Development of adaptive immunity after COVID-19 and after vaccination against SARS-CoV-2 is predicated on recognition of viral peptides, presented on HLA class II molecules, by CD4+ T-cells. We capitalised on extensive...
A Comparison of HLA Molecular Mismatch Methods to Determine HLA Immunogenicity.
BACKGROUND: Antibody-mediated rejection is a major cause of premature graft loss in kidney transplantation. Multiple scoring systems are available to assess the HLA mismatch between donors and recipients at the molecular level;...
Adolescent Adult Antibodies Disease-Free Survival Follow-Up Studies Graft Survival HLA Antigens Histocompatibility Testing Humans Immunosuppression Therapy Kidney Failure Chronic Kidney Transplantation Middle Aged Multivariate Analysis Proportional Hazards Models Risk Assessment Static Electricity Young Adult
Update of the keratin gene family
Minh Ho, Brian Thompson, Jeffrey Nicholas Fisk, Daniel W Nebert, Elspeth Bruford, Vasilis Vasiliou, Christopher G Bunick
Jan 10, 2022
Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the...
Technical Limitations of the C1q Single-Antigen Bead Assay to Detect Complement Binding HLA-Specific Antibodies.
Craig J Taylor, Vasilis Kosmoliaptsis, Jessie Martin, Graham Knighton, Dermot Mallon, J Andrew Bradley, Sarah Peacock
Apr 21, 2016
Adult Antibody Specificity Complement Activation Complement C1q Female Graft Rejection Graft Survival HLA Antigens Histocompatibility Histocompatibility Testing Humans Immunoglobulin G Isoantibodies Male Middle Aged Predictive Value of Tests Protein Binding Protein Denaturation Protein Folding Reproducibility of Results Young Adult
26-hour Storage of a Declined Liver Before Successful Transplantation Using Ex Vivo Normothermic Perfusion.
Christopher JE Watson, Lucy V Randle, Vasilis Kosmoliaptsis, Paul Gibbs, Michael Allison, Andrew J Butler
Jun 20, 2016
This is the author accepted manuscript. The final version is available at http://dx.doi.org/10.1097/SLA.0000000000001834
White-Matter Pathways for Statistical Learning of Temporal Structures.
Vasilis M Karlaftis, Rui Wang, Yuan Shen, Peter Tino, Guy Williams, Andrew E Welchman, Zoe Kourtzi
Aug 09, 2018
Extracting the statistics of event streams in natural environments is critical for interpreting current events and predicting future ones. The brain is known to rapidly find structure and meaning in unfamiliar streams of sensory...
Colorectal liver metastases
Jack Martin, Angelica Petrillo, Elizabeth C Smyth, Nadeem Shaida, Samir Khwaja, HK Cheow, Adam Duckworth, Paula Heister, Raaj Praseedom, Asif Jah, Anita Balakrishnan, Simon Harper, Siong Liau, Vasilis Kosmoliaptsis, Emmanuel Huguet
Nov 30, 2020
The liver is the commonest site of metastatic disease for patients with colorectal cancer, with at least 25% developing colorectal liver metastases (CRLM) during the course of their illness. The management of CRLM has evolved...
Extracellular Vesicles as Drug Delivery Systems in Organ Transplantation
Extracellular vesicles are lipid bilayer-delimited nanoparticles excreted into the extracellular space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full complement of RNA species, which they...
Organ Transplantation ischemia reperfusion injury allograft rejection Drug Delivery Systems Exosomes extracellular vesicles Machine perfusion
Published by: Pharmaceutics
Gonadotrophin-independent Precocious Puberty Secondary to an Estrogen Secreting Adrenal Tumor.
Xanthippi Tseretopoulou, Matthew J Murray, Jackie Buck, C Elizabeth Hook, Claire Jackson, Vasilis Kosmoliaptsis, Jacqueline Hughes, Samantha Gorman, Rachel M Williams
Apr 16, 2021
BACKGROUND: Adrenal masses are rare in children and most commonly present with clinical features of virilization in the absence of activation of the pituitary axis-gonadotrophin-independent precocious puberty. OBSERVATIONS: We...
Ureteric complications in recipients of kidneys from donation after circulatory death donors.
Trina-Jo Mah, Dermot H Mallon, Oliver Brewster, Kourosh Saeb-Parsy, Andrew J Butler, J Andrew Bradley, Vasilis Kosmoliaptsis
Mar 29, 2017
DCD kidney transplantation ureteric complications Adolescent Adult Aged Aged 80 and over Brain Death Child Child Preschool Constriction Pathologic Female Follow-Up Studies Glomerular Filtration Rate Humans Incidence Kidney Function Tests Kidney Transplantation Male Middle Aged Postoperative Complications Prognosis Retrospective Studies Risk Factors Tissue Donors Tissue and Organ Procurement United Kingdom Ureter Urologic Diseases Young Adult
Update of the keratin gene family
Minh Ho, Brian Thompson, Jeffrey Nicholas Fisk, Daniel W Nebert, Elspeth A Bruford, Vasilis Vasiliou, Christopher G Bunick
Feb 09, 2022
Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the...
Multimodal imaging of brain connectivity reveals predictors of individual decision strategy in statistical learning.
Vasilis M Karlaftis, Joseph Giorgio, Petra E Vértes, Rui Wang, Yuan Shen, Peter Tino, Andrew E Welchman, Zoe Kourtzi
Jan 17, 2019
1701 Psychology 1109 Neurosciences Biomedical Behavioral and Social Science Neurosciences Bioengineering Brain Disorders Basic Behavioral and Social Science Mental Health Neurological 1.2 Psychological and socioeconomic processes 1.1 Normal biological development and functioning 2.3 Psychological social and economic factors
Update of the keratin gene family
Minh Ho, Brian Thompson, Jeffrey Nicholas Fisk, Daniel W. Nebert, Elspeth A. Bruford, Vasilis Vasiliou, Christopher G. Bunick
Jan 30, 2022
Abstract: Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes...
Fine-scale computations for adaptive processing in the human brain
Elisa Zamboni, Valentin G Kemper, Nuno Reis Goncalves, Ke Jia, Vasilis M Karlaftis, Samuel J Bell, Joseph Giorgio, Reuben Rideaux, Rainer Goebel, Zoe Kourtzi
Nov 26, 2020
Adapting to the environment statistics by reducing brain responses to repetitive sensory information is key for efficient information processing. Yet, the fine-scale computations that support this adaptive processing in the...
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