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Results: 288
Platelets from patients with visceral obesity promote colon cancer growth.
Marica Cariello, Elena Piccinin, Emanuela Pasculli, Maria Arconzo, Roberta Zerlotin, Simona D'Amore, Francesca Mastropasqua, Claudia Peres, Giusi Graziano, Gaetano Villani, Graziano Pesole, Antonio Moschetta
Jul 08, 2022
Several studies highlighted the importance of platelets in the tumor microenvironment due to their ability to interact with other cell types such as leukocytes, endothelial, stromal and cancer cells. Platelets can influence...
Smart Technologies, Back-to-the-Village Rhetoric, and Tactical Urbanism
Teresa Graziano
Apr 01, 2021
This viewpoint article is aimed at critically scrutinizing both institutional and bottom-up narratives about post-COVID planning scenarios in Italy. Through a critical multimedia discourse analysis, the article tries to...
Published by: IGI Global Scientific Publishing
Social impacts of European Protected Areas and policy recommendations.
Effective designation of Protected Areas (PAs) requires the careful consideration of their social impacts as these are perceived by people. These refer to a variety of issues such as the distribution of power, social equity...
A common molecular logic determines embryonic stem cell self-renewal and reprogramming.
abstract boolean network formal verification maintenance and reprogramming naive pluripotency transcription factor network modelling Animals CRISPR-Cas Systems Cell Differentiation Cell Self Renewal Cells Cultured Cellular Reprogramming Computational Biology Embryonic Stem Cells Epigenesis Genetic Gene Expression Profiling Gene Expression Regulation Developmental Gene Regulatory Networks Mice Mouse embryonic stem cells Pluripotent Stem Cells
Phylogenetic analyses of complete mitochondrial genome sequences suggest a basal divergence of the enigmatic rodent Anomalurus.
David S Horner, Konstantinos Lefkimmiatis, Aurelio Reyes, Carmela Gissi, Cecilia Saccone, Graziano Pesole
Nov 23, 2017
BACKGROUND: Phylogenetic relationships between Lagomorpha, Rodentia and Primates and their allies (Euarchontoglires) have long been debated. While it is now generally agreed that Rodentia constitutes a monophyletic sister-group...
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency.
LIF STAT3 metabolism mitochondrial respiration Pluripotency Animals Cell Differentiation Cell Proliferation Cell Respiration Chromatin Immunoprecipitation Embryonic Stem Cells Gene Expression Regulation Leukemia Inhibitory Factor Mice Mitochondria Pluripotent Stem Cells STAT3 Transcription Factor Transcription Genetic
Identification of peculiar gene expression profile in peripheral blood mononuclear cells (PBMC) of celiac patients on gluten free diet.
Moris Sangineto, Giusi Graziano, Simona D'Amore, Roberto Salvia, Giuseppe Palasciano, Carlo Sabbà, Michele Vacca, Marica Cariello
Sep 20, 2018
Celiac disease (CD) is a systemic disorder characterized by an immune-mediated reaction to gluten and a wide spectrum of clinical manifestations. Currently, the main treatment of CD is represented by adherence to a gluten-free...
Hepatic microRNA Expression by PGC-1α and PGC-1β in the Mouse.
Elena Piccinin, Maria Arconzo, Giusi Graziano, Michele Vacca, Claudia Peres, Elena Bellafante, Gaetano Villani, Antonio Moschetta
Feb 03, 2020
The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ coactivators (PGC-1s) are transcriptional key players...
Systematic Review and Meta-Analysis of Randomised Trials to Ascertain Fatal Gastrointestinal Bleeding Events Attributable to Preventive Low-Dose Aspirin
Peter C Elwood, Gareth Morgan, Julieta Galante, John WK Chia, Sunil Dolwani, J Michael Graziano, Mark Kelson, Angel Lanas, Marcus Longley, Ceri J Phillips, Janet Pickering, Stephen E Roberts, Swee S Soon, Will Steward, Delyth Morris, Alison L Weightman
Feb 15, 2019
BACKGROUND: Aspirin has been shown to lower the incidence and the mortality of vascular disease and cancer but its wider adoption appears to be seriously impeded by concerns about gastrointestinal (GI) bleeding. Unlike heart...
Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer
Antonino Grassadonia, Vincenzo Graziano, Laura Iezzi, Patrizia Vici, Maddalena Barba, Laura Pizzuti, Giuseppe Cicero, Eriseld Krasniqi, Marco Mazzotta, Daniele Marinelli, Antonella Amodio, Clara Natoli, Nicola Tinari
Jul 07, 2021
The neutrophil to lymphocyte ratio (NLR) is a promising predictive and prognostic factor in breast cancer. We investigated its ability to predict disease-free survival (DFS) and overall survival (OS) in patients with luminal A-...
Tissue-specific mtDNA abundance from exome data and its correlation with mitochondrial transcription, mass and respiratory activity.
Tgf-β1 transcriptionally promotes 90K expression
Antonino Grassadonia, Vincenzo Graziano, Sara Pagotto, Angelo Veronese, Cesidio Giuliani, Marco Marchisio, Paola Lanuti, Michele De Tursi, Maurizia D’Egidio, Pietro Di Marino, Davide Brocco, Patrizia Vici, Laura De Lellis, Alessandro Cama, Clara Natoli, Nicola Tinari
May 11, 2021
Abstract: The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In studies on a non-immune cell model, the rat FRTL-5 cell...
Metabolic control of DNA methylation in naive pluripotent cells.
Riccardo M Betto, Linda Diamante, Valentina Perrera, Matteo Audano, Stefania Rapelli, Andrea Lauria, Danny Incarnato, Mattia Arboit, Silvia Pedretti, Giovanni Rigoni, Vincent Guerineau, David Touboul, Giuliano Giuseppe Stirparo, Tim Lohoff, Thorsten Boroviak, Paolo Grumati, Maria E Soriano, Jennifer Nichols, Nico Mitro, Salvatore Oliviero, Graziano Martello
Feb 09, 2021
Naive epiblast and embryonic stem cells (ESCs) give rise to all cells of adults. Such developmental plasticity is associated with genome hypomethylation. Here, we show that LIF-Stat3 signaling induces genomic hypomethylation via...
Animals Blastocyst Cell Differentiation Cells Cultured DNA (Cytosine-5-)-Methyltransferases DNA Methylation DNA Methyltransferase 3A Embryonic Stem Cells Gene Expression Regulation Histones Ketoglutaric Acids Leukemia Inhibitory Factor Mice Knockout Nerve Tissue Proteins Otx Transcription Factors Pluripotent Stem Cells Promoter Regions Genetic STAT3 Transcription Factor
Tgf-β1 transcriptionally promotes 90K expression
Antonino Grassadonia, Vincenzo Graziano, Sara Pagotto, Angelo Veronese, Cesidio Giuliani, Marco Marchisio, Paola Lanuti, Michele De Tursi, Maurizia D’Egidio, Pietro Di Marino, Davide Brocco, Patrizia Vici, Laura De Lellis, Alessandro Cama, Clara Natoli, Nicola Tinari
May 12, 2021
Abstract: The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In studies on a non-immune cell model, the rat FRTL-5 cell...
Tgf-β1 transcriptionally promotes 90K expression
Antonino Grassadonia, Vincenzo Graziano, Sara Pagotto, Angelo Veronese, Cesidio Giuliani, Marco Marchisio, Paola Lanuti, Michele De Tursi, Maurizia D'Egidio, Pietro Di Marino, Davide Brocco, Patrizia Vici, Laura De Lellis, Alessandro Cama, Clara Natoli, Nicola Tinari
Aug 02, 2021
The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In studies on a non-immune cell model, the rat FRTL-5 cell line, we...
Identification of miR-9-5p as direct regulator of ABCA1 and HDL-driven reverse cholesterol transport in circulating CD14+ cells of patients with metabolic syndrome.
Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer
Antonino Grassadonia, Vincenzo Graziano, Laura Iezzi, Patrizia Vici, Maddalena Barba, Laura Pizzuti, Giuseppe Cicero, Eriseld Krasniqi, Marco Mazzotta, Daniele Marinelli, Antonella Amodio, Clara Natoli, Nicola Tinari
Sep 08, 2021
The neutrophil to lymphocyte ratio (NLR) is a promising predictive and prognostic factor in breast cancer. We investigated its ability to predict disease-free survival (DFS) and overall survival (OS) in patients with luminal A-...
An unexpected role reversal
Abstract
In 1862, the collector Pavel Tretyakov made his second visit to Britain, and lent three paintings to the International Exhibition held in London that year. Then aged just thirty, he had...
RP Blakesley
Apr 19, 2017
Tgf-β1 transcriptionally promotes 90K expression
Antonino Grassadonia, Vincenzo Graziano, Sara Pagotto, Angelo Veronese, Cesidio Giuliani, Marco Marchisio, Paola Lanuti, Michele De Tursi, Maurizia D’Egidio, Pietro De Marino, Davide Brocco, Patrizia Vici, Laura De Lellis, Alessandro Cama, Clara Natoli, Nicola Tinari
Apr 22, 2021
Abstract: The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In studies on a non-immune cell model, the rat FRTL-5 cell...
Circulating Cancer Stem Cell-Derived Extracellular Vesicles as a Novel Biomarker for Clinical Outcome Evaluation.
D Brocco, P Lanuti, P Simeone, G Bologna, D Pieragostino, M C Cufaro, V Graziano, M Peri, P Di Marino, M De Tursi, A Grassadonia, I G Rapposelli, L Pierdomenico, E Ercolino, F Ciccocioppo, P Del Boccio, M Marchisio, C Natoli, S Miscia, N Tinari
Jan 12, 2020
The recent introduction of the "precision medicine" concept in oncology pushed cancer research to focus on dynamic measurable biomarkers able to predict responses to novel anticancer therapies in order to improve clinical...
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