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Results: 79
Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.
Edward Britton, Connor Rogerson, Shaveta Mehta, Yaoyong Li, Xiaodun Li, OCCAMS consortium, Rebecca C Fitzgerald, Yeng S Ang, Andrew D Sharrocks
Nov 01, 2018
Adenocarcinoma Adenovirus E1A Proteins Cell Line Tumor Chromatin Chromatin Assembly and Disassembly DNA-Binding Proteins Esophageal Neoplasms Gene Expression Regulation Neoplastic Gene Knockdown Techniques Humans Proto-Oncogene Proteins Proto-Oncogene Proteins c-ets Transcription Factor AP-1 Transcription Factors Transcriptional Activation
Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule
Human angiogenin (ANG) is an angiogenic molecule and a ribonucleolytic enzyme with significant amino acid sequence identity to pancreatic RNase A, plays a critical role in the establishment and growth of tumours. An association...
British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus.
Rebecca C Fitzgerald, Massimiliano di Pietro, Krish Ragunath, Yeng Ang, Jin-Yong Kang, Peter Watson, Nigel Trudgill, Praful Patel, Philip V Kaye, Scott Sanders, Maria O'Donovan, Elizabeth Bird-Lieberman, Pradeep Bhandari, Janusz A Jankowski, Stephen Attwood, Simon L Parsons, Duncan Loft, Jesper Lagergren, Paul Moayyedi, Georgios Lyratzopoulos, John de Caestecker, British Society of Gastroenterology
Sep 05, 2018
These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia. The Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument...
BARRETT'S CARCINOMA BARRETT'S METAPLASIA BARRETT'S OESOPHAGUS gastroesophageal reflux disease OESOPHAGEAL CANCER Ablation Techniques Adenocarcinoma Barrett Esophagus Biopsy Cost-Benefit Analysis Decision Support Techniques Early Detection of Cancer Esophageal Neoplasms Esophagectomy Esophagoscopy esophagus Humans Risk Assessment Risk Factors United Kingdom United States
Multimodal Integration and Vividness in the Angular Gyrus During Episodic Encoding and Retrieval.
Much evidence suggests that the angular gyrus (AnG) is involved in episodic memory, but its precise role has yet to be determined. We examined two possible accounts within the same experimental paradigm: the "cortical binding of...
Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule
Human angiogenin (ANG) is an angiogenic molecule and a ribonucleolytic enzyme with significant amino acid sequence identity to pancreatic RNase A, plays a critical role in the establishment and growth of tumours. An association...
The secretion of the angiogenic and neurotrophic factor angiogenin is COPII and microtubule dependent
The RNaseA superfamily member Angiogenin (ANG)is a secreted protein involved in neovascularization, cell proliferation and stress response. Dysregulation of ANG expression is found in many cancers with poor prognosis and...
The secretion of the angiogenic and neurotrophic factor angiogenin is COPII and microtubule dependent
The RNaseA superfamily member Angiogenin (ANG)is a secreted protein involved in neovascularization, cell proliferation and stress response. Dysregulation of ANG expression is found in many cancers with poor prognosis and...
Emerging Auditory Selectivity in the Caudomedial Neostriatum of the Zebra Finch Songbird
Caroline Wan-Yin Ang
Jan 01, 0001
The ability to identify and interpret auditory stimuli from the environmental milieu is of particular importance in species that communicate using learned vocalizations. By chronically recording multiunit neuronal responses in...
Published by: Rockefeller University
Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes
BACKGROUND: The causal role of interleukins (ILs) for cardiovascular disease has not been fully elucidated. We conducted a Mendelian randomization study to investigate the associations of circulating ILs with coronary artery...
Atrial fibrillation Coronary Artery Disease immune Interleukins ischemic stroke Mendelian Randomization Analysis Atrial fibrillation Brain Ischemia Coronary Artery Disease Genome-Wide Association Study Humans Interleukins ischemic stroke Mendelian Randomization Analysis Polymorphism Single Nucleotide Risk Factors stroke
A Bamboo-inspired Exoskeleton (BiEXO) Based on Carbon Fiber for Shoulder and Elbow Joints
This paper presents a novel cable-driven exoskeleton (BiEXO) for the upper limb including shoulder and elbow joints. BiEXO is made of carbon fiber that is inspired by the Bamboo structure. The key components of BiEXO are...
A Bamboo-inspired Exoskeleton (BiEXO) Based on Carbon Fiber for Shoulder and Elbow Joints
This paper presents a novel cable-driven exoskeleton (BiEXO) for the upper limb including shoulder and elbow joints. BiEXO is made of carbon fiber that is inspired by the Bamboo structure. The key components of BiEXO are...
Authentication and characterisation of a new oesophageal adenocarcinoma cell line
Edwin Garcia, Annette Hayden, Charles Birts, Edward Britton, Andrew Cowie, Karen Pickard, Massimiliano Mellone, Clarisa Choh, Mathieu Derouet, Patrick Duriez, Fergus Noble, Michael J White, John N Primrose, Jonathan C Strefford, Matthew Rose-Zerilli, Gareth J Thomas, Yeng Ang, Andrew D Sharrocks, Rebecca C Fitzgerald, Timothy J Underwood, OCCAMS consortium
Sep 28, 2016
The functional role of sequentially neuromodulated synaptic plasticity in behavioural learning.
Grace Wan Yu Ang, Clara S Tang, Y Audrey Hay, Sara Zannone, Ole Paulsen, Claudia Clopath
Jul 26, 2021
To survive, animals have to quickly modify their behaviour when the reward changes. The internal representations responsible for this are updated through synaptic weight changes, mediated by certain neuromodulators conveying...
HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome.
Cell Line Tumor Chromatin Chromatin Assembly and Disassembly Cyclin-Dependent Kinase 9 Epigenesis Genetic Female Gene Expression Regulation Neoplastic Gene Expression Regulation Viral Genome Viral Human papillomavirus 16 Humans Oncogene Proteins Viral Papillomavirus E7 Proteins Repressor Proteins Uterine Cervical Neoplasms Virus Integration
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers
Enhanced calcium entry via activation of NOX/PKC underlies increased vasoconstriction induced by methylglyoxal
Basma Ghazi Eid, Alaa Abu Sharib, Hany M El-Bassossy, Khadijah Balamash, Sergey Smirnov
Dec 02, 2018
Advanced glycation end-products (AGEs) play a pivotal role in macro- and micro-vascular diabetic complications. We investigated the mechanism by which methylglyoxal (an endogenous generator of AGEs) affects vascular...
Implications of abnormal abdominal wall computed tomographic angiography findings on postmastectomy free flap breast reconstruction.
Ledibabari Mildred Ngaage, Raed R Hamed, Georgette Oni, Dina T Ghorra, Jolenda Z Ang, Brendan C Koo, Sarah L Benyon, Michael S Irwin, Charles M Malata
Apr 24, 2020
BACKGROUND: Preoperative computed tomography angiography (CTA) of the abdominal wall vessels is used when planning free flap breast reconstruction (FFBR) because it provides a surgical road map which facilitates flap harvest....
(Offloading) QoE-Aware Application Mapping and Energy-Aware Module Placement in Fog Computing + Offloading
Fog computing is a potential solution for the Internet of Things in close connection with things and end-users. Fog computing will easily transfer sensitive data without delaying distributed devices. Moreover, fog computing is...
Published by: IGI Global Scientific Publishing
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Marc Clément, Joel Chappell, Juliette Raffort, Fabien Lareyre, Marie Vandestienne, Annabel L Taylor, Alison Finigan, James Harrison, Martin R Bennett, Patrick Bruneval, Soraya Taleb, Helle F Jørgensen, Ziad Mallat
Mar 29, 2019
Objective- Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However, lineage-tracing studies are still lacking, and the...
Angiotensin II Autophagy clones Endoplasmic Reticulum Inflammation Mice Smooth muscle cells Adult Aged aortic dissection Angiotensin II Animals Aorta Aortic Aneurysm Autophagy Autophagy-Related Protein 5 Cell Lineage Cell Plasticity Cells Cultured Disease Models Animal Endoribonucleases Female Humans Male Mice 129 Strain Mice Inbred C57BL Mice Knockout ApoE Middle Aged Muscle Smooth Vascular Myocytes Smooth Muscle Phenotype Protein Serine-Threonine Kinases Signal Transduction
Enhanced calcium entry via activation of NOX/PKC underlies increased vasoconstriction induced by methylglyoxal
Basma Ghazi Eid, Alaa Abu Sharib, Hany M El-Bassossy, Khadijah Balamash, Sergey Smirnov
Dec 02, 2018
Advanced glycation end-products (AGEs) play a pivotal role in macro- and micro-vascular diabetic complications. We investigated the mechanism by which methylglyoxal (an endogenous generator of AGEs) affects vascular...
Ecological networks of dissolved organic matter and microorganisms under global change.
Ang Hu, Mira Choi, Andrew J Tanentzap, Jinfu Liu, Kyoung-Soon Jang, Jay T Lennon, Yongqin Liu, Janne Soininen, Xiancai Lu, Yunlin Zhang, Ji Shen, Jianjun Wang
Jul 24, 2022
Microbes regulate the composition and turnover of organic matter. Here we developed a framework called Energy-Diversity-Trait integrative Analysis to quantify how dissolved organic matter and microbes interact along global...
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