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Fluorescent small organic probes for biosensing
Small-molecule based fluorescent probes are increasingly important for the detection and imaging of biological signaling molecules due to their simplicity, high selectivity and sensitivity, whilst being non-invasive, and...
Fluorescent small organic probes for biosensing
Small-molecule based fluorescent probes are increasingly important for the detection and imaging of biological signaling molecules due to their simplicity, high selectivity and sensitivity, whilst being non-invasive, and...
Coumarin-based fluorescent probe for the detection of glutathione and nitroreductase
Xue Tian, Lokesh K. Kumawat, Steven D. Bull, Robert B. P. Elmes, Luling Wu, Tony D. James
Feb 26, 2021
With this research we set out to develop a coumarin-based novel fluorescent probe NTR-AHC for the detection of biological thiols and nitroreductase (NTR). Probe NTR-AHC was constructed by attaching the NTR trigger moiety...
Coumarin-based fluorescent probe for the detection of glutathione and nitroreductase
Xue Tian, Lokesh K. Kumawat, Steven D. Bull, Robert B. P. Elmes, Luling Wu, Tony D. James
Feb 26, 2021
With this research we set out to develop a coumarin-based novel fluorescent probe NTR-AHC for the detection of biological thiols and nitroreductase (NTR). Probe NTR-AHC was constructed by attaching the NTR trigger moiety...
Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder.
Yan-Yu Wang, Yi Wang, Ying-Min Zou, Ke Ni, Xue Tian, Hong-Wei Sun, Simon SY Lui, Eric FC Cheung, John Suckling, Raymond CK Chan
Jun 21, 2018
BACKGROUND: Although Theory of Mind (ToM) impairment has been observed in patients with a wide range of mental disorders, the similarity and uniqueness of these deficits across diagnostic groups has not been thoroughly...
New insights into the DT40 B cell receptor cluster using a proteomic proximity labeling assay.
Xue-Wen Li, Johanna S Rees, Peng Xue, Hong Zhang, Samir W Hamaia, Bailey Sanderson, Phillip E Funk, Richard W Farndale, Kathryn S Lilley, Sarah Perrett, Antony P Jackson
Jan 18, 2016
B Cell Receptor Evi2a immunology integrin Lymphocyte Mass Spectrometry (MS) Proteomics Raftlin SILAC chB6 Animals Avian Proteins B-Lymphocytes Biotin Cell Line Tumor Chickens Integrins Isoantigens Isotope Labeling Membrane Microdomains Microscopy Confocal Microscopy Fluorescence Protein Binding Proteome Proteomics Receptors Antigen B-Cell Staining and Labeling Tyramine
Stable Maps in Higher Dimensions
We formulate a notion of stability for maps between polarised varieties which generalises Kontsevich's definition when the domain is a curve and Tian-Donaldson's definition of K-stability when the ...
A sol-gel monolithic metal-organic framework with enhanced methane uptake.
Tian Tian, Zhixin Zeng, Diana Vulpe, Mirian E Casco, Giorgio Divitini, Paul A Midgley, Joaquin Silvestre-Albero, Jin-Chong Tan, Peyman Z Moghadam, David Fairen-Jimenez
Apr 13, 2018
A critical bottleneck for the use of natural gas as a transportation fuel has been the development of materials capable of storing it in a sufficiently compact form at ambient temperature. Here we report the synthesis of a...
Development of Novel Chemical Biology Tools for Probing Structure-Function Relationships in G Protein-Coupled Receptors
Tian He
Jan 01, 0001
G protein-coupled receptors (GPCRs) constitute a large family of transmembrane receptors that transduce extracellular signals into intracellular biochemical responses. Understanding with chemical precision how GPCRs function in...
Published by: Rockefeller University
Chinese Officials Attend U.S.-China Trade Forum at Winthrop on Oct. 24
Winthrop University
Jan 01, 0001
Quick Facts
Attending the event are the Chinese Embassy Minister Counselor Tian Deyou, his delegation, U.S. Rep. Ralph Norman, (R-S.C.) and key business leaders from South Carolina. The forum lasts from 4:30 to 6:30 p.m. in the...
Published by: Winthrop University
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.
Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Li-Peng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai, Wanglong Gou, Congmei Xiao, Zhangzhi Xue, Yuting Xie, Sainan Li, Sha Lu, Meiqi Shi, Xuhong Wang, Wensheng Hu, Claudia Langenberg, Jian Yang, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Mar 19, 2023
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...
Humans Cardiovascular Diseases Genetic Predisposition to Disease Proteome Genotype Phenotype Polymorphism Single Nucleotide Genome-Wide Association Study
Published by: Nature Communications
A general approach for hysteresis-free, operationally stable metal halide perovskite field-effect transistors.
Satyaprasad P Senanayak, Mojtaba Abdi-Jalebi, Varun S Kamboj, Remington Carey, Ravichandran Shivanna, Tian Tian, Guillaume Schweicher, Junzhan Wang, Nadja Giesbrecht, Daniele Di Nuzzo, Harvey E Beere, Pablo Docampo, David A Ritchie, David Fairen-Jimenez, Richard H Friend, Henning Sirringhaus
May 18, 2020
Despite sustained research, application of lead halide perovskites in field-effect transistors (FETs) has substantial concerns in terms of operational instabilities and hysteresis effects which are linked to its ionic nature....
Published by: Science advances
Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly
John Zhao Xue
Jan 01, 0001
The eukaryotic nucleus mediates the genomic functions of information storage and gene expression, but must be completely rebuilt after every open mitosis as well as during fertilization. Nuclear abnormalities are observed in...
Published by: Rockefeller University
Alpha invariants and coercivity of the Mabuchi functional on Fano manifolds
Ruadhaí Dervan
Apr 20, 2016
We give a criterion for the coercivity of the Mabuchi functional for general Kàhler classes on Fano manifolds in terms of Tian's alpha invariant. This generalises a result of Tian in the anti-canonical case implying the...
A general approach for hysteresis-free, operationally stable metal halide perovskite field-effect transistors.
Satyaprasad P Senanayak, Mojtaba Abdi-Jalebi, Varun S Kamboj, Remington Carey, Ravichandran Shivanna, Tian Tian, Guillaume Schweicher, Junzhan Wang, Nadja Giesbrecht, Daniele Di Nuzzo, Harvey E Beere, Pablo Docampo, David A Ritchie, David Fairen-Jimenez, Richard H Friend, Henning Sirringhaus
Sep 14, 2020
Despite sustained research, application of lead halide perovskites in field-effect transistors (FETs) has substantial concerns in terms of operational instabilities and hysteresis effects which are linked to its ionic nature....
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.
Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Li-Peng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai, Wanglong Gou, Congmei Xiao, Zhangzhi Xue, Yuting Xie, Sainan Li, Sha Lu, Meiqi Shi, Xuhong Wang, Wensheng Hu, Claudia Langenberg, Jian Yang, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Feb 17, 2023
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...
Electrical dual-percolation in MWCNTs/SBS/PVDF based thermoplastic elastomer (TPE) composites and the effect of mechanical stretching
Christopher Ellingford, Henry Smith, Xue Yan, Christopher Bowen, Łukasz Figiel, Tony McNally, Chaoying Wan
Mar 01, 2019
Dielectric thermoplastic elastomers (TPEs) offer a number of advantages over traditional dielectric elastomers or rubbers in terms of tailorable mechanical and electrical properties, higher mechanical strain, and ease of...
A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells
Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li
Feb 21, 2018
This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has...
Wireless Monitoring of Small Strains in Intelligent Robots via a Joule Heating Effect in Stretchable Graphene–Polymer Nanocomposites
Flexible strain sensors are an important component for future intelligent robotics. However, the majority of current strain sensors must be electrically connected to a corresponding monitoring system via conducting wires...
A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells
Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li
Feb 21, 2018
This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has...
Dynamic friction modelling without drift and its application in the simulation of a valve controlled hydraulic cylinder system
The frictional modelling literature is reviewed, and it is demonstrated that unrealistic drift results when the shape coefficient is 1.0 for the LuGre and the integral friction models. Drift will not occur but other dynamic...
Power Bases and Power Tensions
Meng Tian
Dec 31, 2021
This paper explores power bases and power tensions among education bureaux, inspection offices, and schools in China. The six bases of social power were applied as the analytical framework to scrutinize 13 policy documents and...
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