A 68-year-old woman undergoing a routine surveillance endoscopy—part of her follow-up for a Barrett's oesophagus—was found to have a solitary, black lesion, approximately 4 mm in diameter, in the gastric body (figure).
Early detection of esophageal neoplasia enables curative endoscopic therapy, but the current diagnostic standard of care has low sensitivity because early neoplasia is often inconspicuous with conventional white-light endoscopy....
Early detection, including cancer screening and surveillance, is emerging as one of the most important topics in modern oncology. Because symptomatic presentation remains the predominant route to cancer diagnosis, there is a...
Oesophageal adenocarcinoma (OAC) has increased dramatically in Western countries, including the UK, over the past 30 years. It usually presents de novo, but is often preceded by Barrett's oesophagus (BO), a premalignant...
BACKGROUND: Proton-pump inhibitors (PPIs) are the mainstay of gastroesophageal reflux disease (GERD) treatment, however, up to 30% of patients have a poor symptomatic response. PH-impedance is the gold standard to assess whether...
Hyperspectral imaging (HSI) enables visualisation of morphological and biochemical information, which could improve disease diagnostic accuracy. Unfortunately, the wide range of image distortions that arise during flexible...
BACKGROUND AND AIMS: The diagnosis of gastric premalignant conditions (GPCs) relies on endoscopy with mucosal sampling. We hypothesized that the endoscopist biopsy rate (EBR) might constitute a quality indicator for EGD, and we...
Emerging clinical interest in combining standard white light endoscopy with targeted near-infrared (NIR) fluorescent contrast agents for improved early cancer detection has created demand for multimodal imaging endoscopes. We...
SIGNIFICANCE: The early detection of dysplasia in patients with Barrett's esophagus could improve outcomes by enabling curative intervention; however, dysplasia is often inconspicuous using conventional white-light endoscopy....
BACKGROUND & AIMS: Diagnosis and surveillance of Barrett's esophagus (BE) and eosinophilic esophagitis (EoE) have become emerging public health issues. Cytosponge is a novel, minimally invasive esophageal cell collection device....
This study examines two aspects of the role of gender in linguistic attitudes. First, it studies the issue of the dimensions which underlie linguistic attitudes, in particular whether features of masculinity and femininity play...
This study examines two aspects of the role of gender in linguistic attitudes. First, it studies the issue of the dimensions which underlie linguistic attitudes, in particular whether features of masculinity and femininity play...
Methods XII, the Twelfth International Conference on Methods in Dialectology,was held at the Universite de Moncton in Moncton, New Brunswick, Canada,from I to 5 August 2005, The event was hosted by the Centre de recherche...
Methods XII, the Twelfth International Conference on Methods in Dialectology,was held at the Universite de Moncton in Moncton, New Brunswick, Canada,from I to 5 August 2005, The event was hosted by the Centre de recherche...
Barrett's esophagus is a pre-malignant lesion that can progress to esophageal adenocarcinoma. We perform a multi-omic analysis of pre-cancer samples from 146 patients with a range of outcomes, comprising 642 person years of...
Barrett's esophagus is a pre-malignant lesion that can progress to esophageal adenocarcinoma. We perform a multi-omic analysis of pre-cancer samples from 146 patients with a range of outcomes, comprising 642 person years of...
Abstract: The semiconductor tracker (SCT) is one of the tracking systems for charged particles in the ATLAS detector. It consists of 4088 silicon strip sensor modules. During Run 2 (2015–2018) the Large Hadron Collider delivered...