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Results: 1778
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Han Seok Koh, Chi Young Chang, Sae-Bom Jeon, Hee Jung Yoon, Ye-Hyeon Ahn, Hyung-Seok Kim, In-Hoo Kim, Sung Ho Jeon, Randall S Johnson, Eun Jung Park
Mar 13, 2020
Inflammation is closely related to the extent of damage following cerebral ischaemia, and the targeting of this inflammation has emerged as a promising therapeutic strategy. Here, we present that hypoxia-induced glial T-cell...
Animals Astrocytes Brain Carotid Artery Common Cell Movement Cells Cultured Hepatitis A Virus Cellular Receptor 2 Hypoxia-Inducible Factor 1 alpha Subunit Hypoxia-Ischemia Brain Immunohistochemistry In Vitro Techniques Inflammation Ligation Magnetic Resonance Imaging Mesencephalon Mice Microglia Neuroglia Neutrophils RNA Messenger Receptors Virus Reverse Transcriptase Polymerase Chain Reaction
IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients
R Tallerico, CM Cristiani, E Staaf, C Garofalo, R Sottile, M Capone, Y Pico de Coaña, G Madonna, E Palella, M Wolodarski, V Carannante, D Mallardo, E Simeone, AM Grimaldi, S Johansson, P Frumento, E Gulletta, A Anichini, F Colucci, G Ciliberto, R Kiessling, K Kärre, PA Ascierto, E Carbone
Jul 20, 2017
Despite the success of immune checkpoint blockade in melanoma, the majority of patients do not respond. We hypothesized that the T and NK cell subset frequencies and expression levels of their receptors may predict responses and...
Governor Appoints Don Long and Tim Hopkins to Winthrop Board of Trustees
Winthrop University
Jan 01, 0001
Don Long of Lake Wylie will fill the appointee slot held by Tommy Pope, who was elected to the S.C. House of Representatives in November and had to resign. Tim Hopkins, an executive director of elementary education in the...
Published by: Winthrop University
Psychology Professor Tim Daugherty Elected as New Chair of Faculty Conference
Winthrop University
Jan 01, 0001
Tim Daugherty, an associate professor of psychology in the College of Arts and Sciences, will replace Marilyn Smith, a professor of business administration who has served since 2002. He will become the faculty chair in July...
Published by: Winthrop University
mHealth Solutions for Mental Health Screening and Diagnosis
Mental health screening and diagnostic apps can provide an opportunity to reduce strain on mental health services, improve patient well-being, and increase access for underrepresented groups. Despite promise of their...
Translating student evaluation of teaching
Student evaluation of teaching (SET) has not yet been studied historically and comparatively. Based on our interviews with professors and administrators at 18 universities in three countries, we discuss how SET diffused in all...
Translating student evaluation of teaching
Student evaluation of teaching (SET) has not yet been studied historically and comparatively. Based on our interviews with professors and administrators at 18 universities in three countries, we discuss how SET diffused in all...
Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an in Vitro Dynamic Gastrointestinal Model
Angela Effinger, Mark McAllister, Irena Tomaszewska, Caitriona M. O'Driscoll, Mark Taylor, Steve Gomersall, James Heaton, Kieran L. Smith, Inese Sarcevica, Sam L. Young, Nikoletta Fotaki
Apr 05, 2021
The aim of the study was to investigate the impact of Crohn's disease (CD) on the performance of a lipid-based formulation of ciprofloxacin in a complex gastrointestinal simulator (TIM-1, TNO) and to compare the luminal...
Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an in Vitro Dynamic Gastrointestinal Model
Angela Effinger, Mark McAllister, Irena Tomaszewska, Caitriona M. O'Driscoll, Mark Taylor, Steve Gomersall, James Heaton, Kieran L. Smith, Inese Sarcevica, Sam L. Young, Nikoletta Fotaki
Apr 05, 2021
The aim of the study was to investigate the impact of Crohn's disease (CD) on the performance of a lipid-based formulation of ciprofloxacin in a complex gastrointestinal simulator (TIM-1, TNO) and to compare the luminal...
Factors Influencing Intention to Use Online Consumer Reviews
Online consumer reviews have been shown to play an important role that can influence consumers' attitudes, behaviors, and purchasing decisions. This study seeks to understand factors that affect user intention to use online...
Published by: IGI Global Scientific Publishing
Greenville Event Planned for Alumni Association's New President
Winthrop University
Jan 01, 0001
Magee, a Greenville, S.C., resident, replaces Tim Hopkins who was recently appointed to the Winthrop Board of Trustees as a designee for S.C. Governor Nikki Haley. The Alumni Association will host a reception welcoming Magee in...
Published by: Winthrop University
AUTHOR BOOK TALK
The Rockefeller University
Jan 01, 0001
Tim M. Berra: Wallace's Acceptance of Darwin's Priority in His Own Words
Published by: The Rockefeller University
Two New Board Members Added to Winthrop Board of Trustees
Winthrop University
Jan 01, 0001
Tommy Pope and Tim Sease will join the Winthrop Board of Trustees in July. Pope has law enforcement and courtroom experience, while Sease oversees an investment company.
Published by: Winthrop University
American Party Event on Sept. 30 Features Co-Founder and U.S. Senate Candidate
Winthrop University
Jan 01, 0001
Jill Bossi of Tega Cay, South Carolina, is running for the U.S. Senate seat held by Tim Scott. Jim Rex, one of the American Party founders and a former S.C. education superintendent, will talk about creation of the party and...
Published by: Winthrop University
A Comparative Study of Trust in Mobile Banking
With the rapid growth of mobile phone usage, mobile services have influenced many industries including banking. Mobile banking has become a popular service as it offers a convenient channel for customers to perform banking...
Published by: IGI Global Scientific Publishing
H2FC SUPERGEN
Chloe Stockford, Nigel Brandon, John Irvine, Tim Mays, Ian Metcalfe, David Book, Paul Ekins, Anthony Kucernak, Vladimir Molkov, Robert Steinberger-Wilckens, Nilay Shah, Paul Dodds, Cristina Dueso, Sheila Samsatli, Claire Thompson
Apr 27, 2015
The United Kingdom has a vast scientific base across the entire Hydrogen and Fuel Cell research landscape, with a world class academic community coupled with significant industrial activity from both UK-based Hydrogen and...
H2FC SUPERGEN
Chloe Stockford, Nigel Brandon, John Irvine, Tim Mays, Ian Metcalfe, David Book, Paul Ekins, Anthony Kucernak, Vladimir Molkov, Robert Steinberger-Wilckens, Nilay Shah, Paul Dodds, Cristina Dueso, Sheila Samsatli, Claire Thompson
Apr 27, 2015
The United Kingdom has a vast scientific base across the entire Hydrogen and Fuel Cell research landscape, with a world class academic community coupled with significant industrial activity from both UK-based Hydrogen and...
Investigating Change Management Based on Participation and Acceptance of IT in the Public Sector
The digitalization of public administrations faces big challenges regarding employees' acceptance of IT. Change management approaches based on participation should help achieving acceptance and success of IT projects in the...
Published by: IGI Global Scientific Publishing
National Corporate Governance Codes and IT Governance Transparency in Annual Reports
IT governance is concerned with the oversight of IT assets, their contribution to business value and the mitigation of IT-related risks. Emerging research calls for more board level engagement in IT governance and identifies...
Published by: IGI Global Scientific Publishing
Digital Transformation and Future Impacts in Logistics and Value Chains
This chapter discusses the opportunities and challenges as well as the effects and impacts on value creation processes, work organization, and corporate management caused by the digital transformation, particularly in the area...
Published by: IGI Global Scientific Publishing
Tim's Town Hall Features U.S. Sen. Rand Paul on Nov. 6
Winthrop University
Jan 01, 0001
The hour-long event will start at noon in the Richardson Ballroom in the Campus Center. This is one in a series of Tim's Town Halls scheduled around the state. U.S. Sen. Tim Scott will welcome GOP presidential hopeful and U.S....
Published by: Winthrop University
Fossils Collected This Summer Will Be Subject of Tests
Winthrop University
Jan 01, 0001
Boyer and two environmental science majors, Tim Swartz and Ty Robbins, took a 13-day trip in June to Utah and Nevada to collect rock samples on federal lands believed to have been the site of mass extinctions. The Winthrop study...
Published by: Winthrop University
Presidential Candidate Forum at Winthrop Wins Regional Special Events Award
Winthrop University
Jan 01, 0001
The Nov. 6, 2015, event was hosted by Winthrop and sponsored by MSNBC with the S.C. Democratic Party. The event, along with a midday visit by Republican U.S. Sen. Rand Paul as part of U.S. Sen. Tim Scott's Town Hall tour, was a...
Published by: Winthrop University
Winthrop President Invited to Join College Basketball Partnership Team
Winthrop University
Jan 01, 0001
DiGiorgio said the College Basketball Partnership will face issues such as recruiting, the balance between academics and athletes, fan behavior and sportsmanship. Others on the College Basketball Partnership include Kentucky...
Published by: Winthrop University
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