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Results: 43
The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER).
Tiia Ngandu, Jenni Lehtisalo, Saana Korkki, Alina Solomon, Nicola Coley, Riitta Antikainen, Lars Bäckman, Tuomo Hänninen, Jaana Lindström, Tiina Laatikainen, Teemu Paajanen, Satu Havulinna, Markku Peltonen, Anna Stigsdotter Neely, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen, Miia Kivipelto
Jul 15, 2022
Severe mood disorders and schizophrenia in the adult offspring of antenatally depressed mothers in the Northern Finland 1966 Birth Cohort
BACKGROUND: Maternal antenatal depression may alter offspring neurodevelopment, but long follow-up studies are lacking. We studied the risks for mood disorders and schizophrenia in adult offspring of antenatally depressed...
Antenatal Bipolar Disorder Depression Mood Disorders Parental mental disorder Schizophrenia Adolescent Adult Adult Children Child Child of Impaired Parents Cohort Studies Depressive Disorder Female Finland Follow-Up Studies Humans Mood Disorders Mother-Child Relations Mothers Pregnancy Pregnancy Complications Prenatal Diagnosis Schizophrenic Psychology Young Adult
Associations between Children's Physical Activity and Neighborhood Environments Using GIS
Melody Smith, Suzanne Mavoa, Erika Ikeda, Kamyar Hasanzadeh, Jinfeng Zhao, Tiina E Rinne, Niamh Donnellan, Marketta Kyttä, Jianqiang Cui
Mar 18, 2022
Regular participation in physical activity is essential for children's physical, mental, and cognitive health. Neighborhood environments may be especially important for children who are more likely to spend time in the...
Modulating dream experience
Valdas Noreika, Jennifer M Windt, Markus Kern, Katja Valli, Tiina Salonen, Riitta Parkkola, Antti Revonsuo, Ahmed A Karim, Tonio Ball, Bigna Lenggenhager
May 23, 2020
Recently, cortical correlates of specific dream contents have been reported, such as the activation of the sensorimotor cortex during dreamed hand clenching. Yet, despite a close resemblance of such activation patterns to those...
Published by: Scientific reports
The influence of membrane charge and porosity upon fouling and cleaning during the ultrafiltration of orange juice
Nurul Hainiza Abd-Razak, Arto Pihlajamäki, Tiina Virtanen, Y. M. John Chew, Michael R. Bird
Mar 31, 2021
The ultrafiltration of orange juice has been performed to separate phytosterols from proteins. Commercial regenerated cellulose acetate (RCA) ultrafiltration membranes of different molecular weight cut offs (MWCOs) of 10 kDa...
The influence of membrane charge and porosity upon fouling and cleaning during the ultrafiltration of orange juice
Nurul Hainiza Abd-Razak, Arto Pihlajamäki, Tiina Virtanen, Y. M. John Chew, Michael R. Bird
Mar 31, 2021
The ultrafiltration of orange juice has been performed to separate phytosterols from proteins. Commercial regenerated cellulose acetate (RCA) ultrafiltration membranes of different molecular weight cut offs (MWCOs) of 10 kDa...
Modulating dream experience
Valdas Noreika, Jennifer M Windt, Markus Kern, Katja Valli, Tiina Salonen, Riitta Parkkola, Antti Revonsuo, Ahmed A Karim, Tonio Ball, Bigna Lenggenhager
Jun 08, 2020
Recently, cortical correlates of specific dream contents have been reported, such as the activation of the sensorimotor cortex during dreamed hand clenching. Yet, despite a close resemblance of such activation patterns to those...
Specific adolescent prodromal symptoms associated with onset of psychosis in the Northern Finland Birth Cohort 1986.
Johanna Palomäki, Sebastian Therman, Martta Kerkelä, Marjo-Riitta Järvelin, Peter Jones, Graham K Murray, Tanja Nordström, Markus Heinimaa, Jouko Miettunen, Juha Veijola, Tiina Riekki
Oct 11, 2022
BACKGROUND: Several psychological symptoms in adolescence associate with later development of psychosis. However, it is unclear which symptoms specifically predict psychotic disorders rather than psychiatric disorders in...
An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.
Tiina Karppanen, Tea Kaartokallio, Miira M Klemetti, Seppo Heinonen, Eero Kajantie, Juha Kere, Katja Kivinen, Anneli Pouta, Anne Cathrine Staff, Hannele Laivuori
Sep 29, 2016
BACKGROUND: Preeclampsia is a common and heterogeneous vascular syndrome of pregnancy. Its genetic risk profile is yet unknown and may vary between individuals and populations. The rs4606 3' UTR polymorphism of the Regulator of...
Candidate gene study Preeclampsia Pregnancy Regulator of G-protein signaling 2 3' Untranslated Regions Adult Alleles Biomarkers Body Mass Index Case-Control Studies Female Gene Expression Regulation Genetic Association Studies Genetic Predisposition to Disease Genotype Humans Models Biological Odds Ratio Overweight Polymorphism Single Nucleotide pre-eclampsia Pregnancy RGS Proteins Risk Factors
Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity.
Liam R Wilson, Deniz Vatansever, Tiina Annus, Guy B Williams, Young T Hong, Tim D Fryer, Peter J Nestor, Anthony J Holland, Shahid H Zaman
Jul 10, 2019
Down's syndrome is a chromosomal disorder that invariably results in both intellectual disability and Alzheimer's disease neuropathology. However, only a limited number of studies to date have investigated intrinsic brain...
Alzheimer's Disease Down's syndrome anti-correlation Default mode network functional connectivity Memory Adult Alzheimer Disease Amyloid Aniline Compounds Carbon Radioisotopes Cerebral Cortex Connectome Cross-Sectional Studies Down Syndrome Female Humans Magnetic Resonance Imaging Male Middle Aged Positron-Emission Tomography Radiopharmaceuticals Thiazoles
No association of COMT (Val158Met) genotype with brain structure differences between men and women.
Anna Barnes, Matti Isohanni, Jennifer H Barnett, Olli Pietiläinen, Juha Veijola, Jouko Miettunen, Tiina Paunio, Päivikki Tanskanen, Khanum Ridler, John Suckling, Edward T Bullmore, Graham K Murray, Peter B Jones
May 01, 2018
We examined the effect of the catechol-O-methyltransferase (COMT) Val158Met polymorphism (rs4680), on brain structure in a subset (N = 82) of general population members of the Northern Finland 1966 Birth Cohort, selected through...
Age-related retinal thickness in Down's syndrome
Madeleine J Walpert, Eduardo M Normando, Tiina Annus, Sally R Jennings, Liam R Wilson, Peter Watson, Shahid H Zaman, M Francesca Cordeiro, Anthony J Holland
Feb 07, 2020
Introduction:People with Down's syndrome (DS) have a high prevalence of early-onset Alzheimer's disease. Early markers of Alzheimer's disease pathology identifiable before clinical change are needed for the evaluation of...
AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
Ricardo S Randall, Shunsuke Miyashima, Tiina Blomster, Jing Zhang, Annakaisa Elo, Anna Karlberg, Juha Immanen, Kaisa Nieminen, Ji-Young Lee, Tatsuo Kakimoto, Karolina Blajecka, Charles W Melnyk, Annette Alcasabas, Celine Forzani, Miho Matsumoto-Kitano, Ari Pekka Mähönen, Rishikesh Bhalerao, Walter Dewitte, Ykä Helariutta, James AH Murray
Sep 29, 2018
Higher plant vasculature is characterized by two distinct developmental phases. Initially, a well-defined radial primary pattern is established. In eudicots, this is followed by secondary growth, which involves development of...
Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome
Elijah Mak, Anastasia Bickerton, Concepcion Padilla, Madeleine J Walpert, Tiina Annus, Liam R Wilson, Young T Hong, Tim D Fryer, Jonathan P Coles, Franklin I Aigbirhio, Bradley T Christian, Benjamin L Handen, William E Klunk, David K Menon, Peter J Nestor, Shahid H Zaman, Anthony J Holland
May 23, 2019
Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline.
Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome.
David A Dorward, Christopher D Lucas, Mary K Doherty, Gavin B Chapman, Emma J Scholefield, Andrew Conway Morris, Jennifer M Felton, Tiina Kipari, Duncan C Humphries, Calum T Robb, A John Simpson, Phillip D Whitfield, Christopher Haslett, Kevin Dhaliwal, Adriano G Rossi
Aug 17, 2017
BACKGROUND: Acute respiratory distress syndrome (ARDS) is an often fatal neutrophil-dominant lung disease. Although influenced by multiple proinflammatory mediators, identification of suitable therapeutic candidates remains...
ARDS innate immunity Neutrophil Biology Animals Bronchoalveolar Lavage Fluid Chemotaxis Leukocyte Chromatography High Pressure Liquid Disease Models Animal Flow Cytometry Humans Mice Mitochondria Neutrophil Activation Neutrophils Receptors Formyl Peptide Respiratory Distress Syndrome Tandem Mass Spectrometry
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder
Atiqul Haq Mazumder, Jennifer Barnett, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Jarmo Hietala, Erkki Isometsä, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Solja Niemelä, Jari Tiihonen, Tiina Paunio, Aarno Palotie, Jaana Suvisaari, Juha Veijola
May 24, 2021
The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia...
The pattern of amyloid accumulation in the brains of adults with Down syndrome.
‘Waste the waist’
Fiona Bridget Gillison, Colin Greaves, Afroditi Stathi, Rosemary Ramsay, P Bennett, Gordon Taylor, Margaret Francis, Roger Chandler
May 01, 2012
Objectives. To identify an evidence-based intervention to promote changes in diet and physical activity and adapt it for a UK primary care setting for people with high cardiovascular risk.
Design. A three-stage...
‘Waste the waist’
Fiona Bridget Gillison, Colin Greaves, Afroditi Stathi, Rosemary Ramsay, P Bennett, Gordon Taylor, Margaret Francis, Roger Chandler
May 01, 2012
Objectives. To identify an evidence-based intervention to promote changes in diet and physical activity and adapt it for a UK primary care setting for people with high cardiovascular risk.
Design. A three-stage...
Multimodal correlative imaging and modelling of phosphorus uptake from soil by hyphae of mycorrhizal fungi.
Sam Keyes, Arjen van Veelen, Dan McKay Fletcher, Callum Scotson, Nico Koebernick, Chiara Petroselli, Katherine Williams, Siul Ruiz, Laura Cooper, Robbie Mayon, Simon Duncan, Marc Dumont, Iver Jakobsen, Giles Oldroyd, Andrzej Tkacz, Philip Poole, Fred Mosselmans, Camelia Borca, Thomas Huthwelker, David L Jones, Tiina Roose
Feb 15, 2022
Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome
Juan Fortea, Eduard Vilaplana, Maria Carmona-Iragui, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernández, Miren Altuna, Jordi Pegueroles, Víctor Montal, Silvia Valldeneu, Sandra Giménez, Sofía González-Ortiz, Laia Muñoz, Teresa Estellés, Ignacio Illán-Gala, Olivia Belbin, Valle Camacho, Liam Reese Wilson, Tiina Annus, Ricardo S Osorio, Sebastián Videla, Sylvain Lehmann, Anthony J Holland, Daniel Alcolea, Jordi Clarimón, Shahid H Zaman, Rafael Blesa, Alberto Lleó
Jul 06, 2020
BACKGROUND: Alzheimer's disease and its complications are the leading cause of death in adults with Down syndrome. Studies have assessed Alzheimer's disease in individuals with Down syndrome, but the natural history of biomarker...
Adult Alzheimer Disease Amyloid beta-Peptides Amyloidosis Apolipoproteins E Biomarkers Case-Control Studies Cognitive Dysfunction Cross-Sectional Studies Down Syndrome Fluorodeoxyglucose F18 Humans Magnetic Resonance Imaging Middle Aged Neurofilament Proteins Positron-Emission Tomography prevalence Spain United Kingdom tau Proteins
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