Search
Results: 11
Diphtheria.
Naresh Chand Sharma, Androulla Efstratiou, Igor Mokrousov, Ankur Mutreja, Bhabatosh Das, Thandavarayan Ramamurthy
Feb 13, 2020
Diphtheria is a potentially fatal infection mostly caused by toxigenic Corynebacterium diphtheriae strains and occasionally by toxigenic C. ulcerans and C. pseudotuberculosis strains. Diphtheria is generally an acute respiratory...
Revisiting the Global Epidemiology of Cholera in Conjuction With the Genomics of Vibrio cholerae.
Thandavarayan Ramamurthy, Ankur Mutreja, François-Xavier Weill, Bhabatosh Das, Amit Ghosh, Gopinath Balakrish Nair
Sep 05, 2019
Toxigenic Vibrio cholerae is responsible for 1.4 to 4.3 million cases with about 21,000-143,000 deaths per year. Dominance of O1 and O139 serogroups, classical and El tor biotypes, alterations in CTX phages and the pathogenicity...
Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae.
Thandavarayan Ramamurthy, Ranjan K Nandy, Asish K Mukhopadhyay, Shanta Dutta, Ankur Mutreja, Keinosuke Okamoto, Shin-Ichi Miyoshi, G Balakrish Nair, Amit Ghosh
Oct 14, 2020
The human pathogen Vibrio cholerae is the causative agent of severe diarrheal disease known as cholera. Of the more than 200 "O" serogroups of this pathogen, O1 and O139 cause cholera outbreaks and epidemics. The rest of the...
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae.
Robert C Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja
May 03, 2021
Diphtheria is a respiratory disease caused by the bacterium Corynebacterium diphtheriae. Although the development of a toxin-based vaccine in the 1930s has allowed a high level of control over the disease, cases have increased...
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic.
Thandavarayan Ramamurthy, Agila Kumari Pragasam, Alyce Taylor-Brown, Robert C Will, Karthick Vasudevan, Bhabatosh Das, Sunil Kumar Srivastava, Goutam Chowdhury, Asish K Mukhopadhyay, Shanta Dutta, Balaji Veeraraghavan, Nicholas R Thomson, Naresh C Sharma, Gopinath Balakrish Nair, Yoshifumi Takeda, Amit Ghosh, Gordon Dougan, Ankur Mutreja
Jul 05, 2022
Cholera is a life-threatening infectious disease that remains an important public health issue in several low and middle-income countries. In 1992, a newly identified O139 Vibrio cholerae temporarily displaced the O1 serogroup....
Genomic plasticity associated with antimicrobial resistance in Vibrio cholerae.
Jyoti Verma, Satyabrata Bag, Bipasa Saha, Pawan Kumar, Tarini Shankar Ghosh, Mayanka Dayal, Tarosi Senapati, Seema Mehra, Prasanta Dey, Anbumani Desigamani, Dhirendra Kumar, Preety Rana, Bhoj Kumar, Tushar K Maiti, Naresh C Sharma, Rupak K Bhadra, Ankur Mutreja, G Balakrish Nair, Thandavarayan Ramamurthy, Bhabatosh Das
Jun 17, 2019
Antimicrobial resistance Cholera Genome mobile genetic elements Proteome Anti-Bacterial Agents Cholera Conjugation Genetic DNA Transposable Elements Diarrhea Drug Resistance Multiple Bacterial evolution Molecular Feces Gene Transfer Horizontal genetic variation Genome Bacterial Genomic Islands Humans Imipenem india Interspersed Repetitive Sequences Phenotype Plasmids Prophages Proteome Vibrio cholerae Vibrio cholerae O1 whole genome sequencing
Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic.
Thandavarayan Ramamurthy, Agila Kumari Pragasam, Alyce Taylor-Brown, Robert C Will, Karthick Vasudevan, Bhabatosh Das, Sunil Kumar Srivastava, Goutam Chowdhury, Asish K Mukhopadhyay, Shanta Dutta, Balaji Veeraraghavan, Nicholas R Thomson, Naresh C Sharma, Gopinath Balakrish Nair, Yoshifumi Takeda, Amit Ghosh, Gordon Dougan, Ankur Mutreja
Aug 06, 2022
Cholera is a life-threatening infectious disease that remains an important public health issue in several low and middle-income countries. In 1992, a newly identified O139 Vibrio cholerae temporarily displaced the O1 serogroup....
Genomic history of the seventh pandemic of cholera in Africa.
François-Xavier Weill, Daryl Domman, Elisabeth Njamkepo, Cheryl Tarr, Jean Rauzier, Nizar Fawal, Karen H Keddy, Henrik Salje, Sandra Moore, Asish K Mukhopadhyay, Raymond Bercion, Francisco J Luquero, Antoinette Ngandjio, Mireille Dosso, Elena Monakhova, Benoit Garin, Christiane Bouchier, Carlo Pazzani, Ankur Mutreja, Roland Grunow, Fati Sidikou, Laurence Bonte, Sébastien Breurec, Maria Damian, Berthe-Marie Njanpop-Lafourcade, Guillaume Sapriel, Anne-Laure Page, Monzer Hamze, Myriam Henkens, Goutam Chowdhury, Martin Mengel, Jean-Louis Koeck, Jean-Michel Fournier, Gordon Dougan, Patrick AD Grimont, Julian Parkhill, Kathryn E Holt, Renaud Piarroux, Thandavarayan Ramamurthy, Marie-Laure Quilici, Nicholas R Thomson
Feb 15, 2019
The seventh cholera pandemic has heavily affected Africa, although the origin and continental spread of the disease remain undefined. We used genomic data from 1070 Vibrio cholerae O1 isolates, across 45 African countries and...
Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020.
Craig P Thompson, Nicholas E Grayson, Robert S Paton, Jai S Bolton, José Lourenço, Bridget S Penman, Lian N Lee, Valerie Odon, Juthathip Mongkolsapaya, Senthil Chinnakannan, Wanwisa Dejnirattisai, Matthew Edmans, Alex Fyfe, Carol Imlach, Kreepa Kooblall, Nicholas Lim, Chang Liu, César López-Camacho, Carol McInally, Anna L McNaughton, Narayan Ramamurthy, Jeremy Ratcliff, Piyada Supasa, Oliver Sampson, Beibei Wang, Alexander J Mentzer, Marc Turner, Malcolm G Semple, Kenneth Baillie, ISARIC4C investigators, Heli Harvala, Gavin R Screaton, Nigel Temperton, Paul Klenerman, Lisa M Jarvis, Sunetra Gupta, Peter Simmonds
Jan 18, 2021
BackgroundThe progression and geographical distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United Kingdom (UK) and elsewhere is unknown because typically only symptomatic individuals...
Covid19 SARS-CoV-2 pandemic serology SURVEILLANCE Scotland Adult Antibodies Neutralizing Antibodies Viral Betacoronavirus Blood Donors covid-19 Cluster Analysis Coronavirus Infections Enzyme-Linked Immunosorbent Assay Female Geography Medical Humans Inhibitory Concentration 50 Male Models Immunological Neutralization Tests Pandemics Pneumonia Viral Population Surveillance prevalence SARS-CoV-2 Scotland Sensitivity and Specificity Seroepidemiologic Studies Urban Population