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Neurobehavioural sequelae of social deprivation in rodents revisited
TW Robbins
Apr 11, 2018
The significance of investigating effects of deprivation of social experience in rodents is reviewed in the context of the review by Robbins et al. (1996) in the Journal of Psychopharmacology (10: 39-47). The early development...
ADHD Social Isolation animal model Cognition Dopamine Hippocampus hyperactivity Prefrontal Cortex prepulse inhibition Schizophrenia Serotonin Striatum Animals Attention Deficit Disorder with Hyperactivity Behavior Animal Cognition Dopamine Hippocampus Humans Mental Disorders motivation Rodentia Schizophrenia Serotonin Social Isolation
Commentary on brain-derived neurotrophic factor and the orbitofrontal regulation of behavior
TW Robbins
Jan 26, 2017
Whereas contemporary neuroimaging evidence supports a role for dysfunctioning prefrontal-amygdaloid-striatal circuitry in affective disorders, precise psychological functions of this interaction have still to be revealed, thus...
Habits.
What is a habit? One problem with the concept of habit has been that virtually everyone has their own ideas of what is meant by such a term. Whilst not eschewing folk psychology, it is useful to re-examine dictionary definitions...
Take it or leave it
Adult Brain Case-Control Studies Central Nervous System Stimulants Cocaine Cocaine-Related Disorders Executive Function Female Frontal Lobe Functional Neuroimaging Humans INHIBITION Psychological Magnetic Resonance Imaging Male Motor Cortex Prefrontal Cortex Reaction Time Task Performance and Analysis Young Adult
Creature of Habit
Our daily lives involve high levels of repetition of activities within similar contexts. We buy the same foods from the same grocery store, cook with the same spices, and typically sit at the same place at the dinner table....
Impairments in reinforcement learning do not explain enhanced habit formation in cocaine use disorder.
Appetitive discrimination learning Computational modelling Extinction Habit Hierarchical Bayesian Perseveration Positive feedback Reinforcement sensitivity Bayes Theorem Brain Cocaine-Related Disorders Discrimination Learning Female Habits Humans Magnetic Resonance Imaging Male motivation Photic Stimulation Reinforcement psychology
The NEWMEDS rodent touchscreen test battery for cognition relevant to schizophrenia.
M Hvoslef-Eide, AC Mar, SRO Nilsson, J Alsiö, CJ Heath, LM Saksida, TW Robbins, TJ Bussey
Jul 07, 2015
Attention Cognitive flexibility Drug Discovery Executive Function Long-term memory MOUSE Neuropsychiatric disease rat Response inhibition Working memory Animals Antipsychotic Agents Cognition Cognition Disorders Conditioning Operant Mice Psychomotor Performance Rats Schizophrenia Schizophrenic Psychology
Facilitation of spatial working memory performance following intra-prefrontal cortical administration of the adrenergic alpha1 agonist phenylephrine.
Baclofen Guanfacine Muscimol Noradrenaline Phenylephrine Prefrontal Cortex rat Touchscreen Working memory Adrenergic alpha-1 Receptor Agonists Adrenergic alpha-2 Receptor Agonists Animals Baclofen GABA Agonists Guanfacine Male Memory Short-Term Muscimol Norepinephrine Phenylephrine Prefrontal Cortex Rats Spatial Memory
Cognitive flexibility OCD functional magnetic resonance imaging (fMRI) Response inhibition shifting stopping Adult Arousal Brain Case-Control Studies Caudate Nucleus Cognition Executive Function Frontal Lobe Functional Neuroimaging Humans Magnetic Resonance Imaging Middle Aged Neostriatum Obsessive-Compulsive Disorder Parietal Lobe Task Performance and Analysis Thalamus
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