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Results: 1031
Maxwell-Stefan diffusion coefficient estimation for ternary systems
C D'Agostino
Aug 02, 2017
The Maxwell–Stefan model is a popular diffusion model originally developed to model diffusion of gases, which can be considered thermodynamically ideal mixtures, although its application has been extended to model diffusion in...
On melting and freezing for the 2D radial Stefan problem
We consider the two dimensional free boundary Stefan problem describing the evolution of a spherically symmetric ice ball $\{r\leq \l(t)\}$. We revisit the pioneering analysis of \cite{HeVe} and prove the existence in the radial...
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.
Kasumi Murai, Stefan Dentro, Swee Hoe Ong, Roshan Sood, David Fernandez-Antoran, Albert Herms, Vasiliki Kostiou, Irina Abnizova, Benjamin A Hall, Moritz Gerstung, Philip H Jones
Nov 20, 2022
Aging normal human oesophagus accumulates TP53 mutant clones. These are the origin of most oesophageal squamous carcinomas, in which biallelic TP53 disruption is almost universal. However, how p53 mutant clones expand and...
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
Emilie Abby, Stefan C Dentro, Michael WJ Hall, Joanna C Fowler, Swee Hoe Ong, Roshan Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Benjamin A Hall, Philip H Jones
Feb 16, 2023
NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations drive clonal expansion but impede carcinogenesis. Here we test this...
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
Emilie Abby, Stefan C Dentro, Michael WJ Hall, Joanna C Fowler, Swee Hoe Ong, Roshan Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Benjamin A Hall, Philip H Jones
Feb 19, 2023
NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations drive clonal expansion but impede carcinogenesis. Here we test this...
The Marshall Plan: A Critique of the European Recovery Program
Louis D. Stefan
Jan 01, 0001
This 48 page thesis examines the Marshall Plan for European recovery following World War II.
World War II Marshall Plan world trade Tariffs Aldrich Plan Krug Report Business Economic History Economics European History International Economics Social and Behavioral Sciences
Published by: Ursinus College
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Bartomeu Colom, Maria P Alcolea, Gabriel Piedrafita, Michael WJ Hall, Agnieszka Wabik, Stefan C Dentro, Joanna C Fowler, Albert Herms, Charlotte King, Swee Hoe Ong, Roshan K Sood, Moritz Gerstung, Inigo Martincorena, Benjamin A Hall, Philip H Jones
Apr 28, 2020
ADAM10 Protein Amyloid Precursor Protein Secretases Animals Cell Lineage Diethylnitrosamine Epithelium esophagus Female High-Throughput Nucleotide Sequencing Male Membrane Proteins Mice Inbred C57BL Mice Transgenic Mutation Receptor Notch1 Receptor Notch2 Reproducibility of Results Tumor Suppressor Protein p53
When Emotions Rule Knowledge
Although emotions play an important role in human behavior and knowledge studies, knowledge management (KM) research considers them from specific angles and, to date, has lacked a comprehensive understanding of the emotions...
Published by: IGI Global Scientific Publishing
The Grizzly, September 23, 1996
Jared Rakes, Erin Gambeski, Taneille Smith, Todd Brenneman, Mark Turney, Sean Campbell, Jen Mintzer, Cristin Veit, Kerrie McKinney, Teresa Green, Joel Schofer, Brian Hamrick, Tony Palladino, Andrew Ruhf, Hera Walker
Jan 01, 0001
Internet Censorship Issue Addressed by Stefan Presser Opinions: Life in a Determinist World; Are Guns Necessary? Study Abroad to Have Fun and Learn Get Moving: A Guide to the Benefits of Exercise Anthonisen Exhibit Captures...
Ursinus College Collegeville Pennsylvania newspaper Soccer field hockey Volleyball Football Megan Larkin Berman Art Museum study abroad NRA Ryan Auch ACLU Censorship cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Constructing Seamless Learning Through Game-Based Learning Experiences
Ioana Stefan, Ancuta Gheorghe, Antoniu Stefan, Andriani Piki, Hariklia Tsalapata, Olivier Heidmann
Oct 01, 2022
The goal of this paper is to explore how game-based experiences can be leveraged through mobile technology to activate learner engagement and achieve a seamless connection between formal and informal learning. The paper presents...
Published by: IGI Global Scientific Publishing
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice.
Gabriel Piedrafita, Vasiliki Kostiou, Agnieszka Wabik, Bartomeu Colom, David Fernandez-Antoran, Albert Herms, Kasumi Murai, Benjamin A Hall, Philip H Jones
Apr 15, 2020
In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight into cell...
Social Adventure
Social environments can be challenging for people with intellectual disabilities. These challenges impact a person's social inclusion and participation in their communities. Social skills development requires training and...
Published by: IGI Global Scientific Publishing
A Value Framework for Technology Potentials
This paper proposes a modified approach for analyzing and presenting the value generation, capture, and distribution from organizational adoption of new technologies. The focal technology used is emotion detection, and technical...
Published by: IGI Global Scientific Publishing
Assessing Maturity in Data-Driven Culture
Research on assessing a group's maturity in data-driven culture is rare and fragmented. This article investigates how maturity in data-driven culture can be assessed from a historical perspective. A case study was done on how...
Published by: IGI Global Scientific Publishing
Winthrop's March 25 Organ Series to Welcome German Musicians Who Are Leading Authorities on Bach, Karg-Elert
Winthrop University
Jan 01, 0001
Winthrop University's International Organ Series brings to campus two German musicians who share a Leipzig connection for a March 25 event entitled "Bach and Beyond -- the Leipzig Organ Tradition." Christoph Wolff is considered...
Published by: Winthrop University
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
Gabriel Piedrafita, Vasiliki Kostiou, Agnieszka Wabik, Bartomeu Colom, David Fernandez-Antoran, Albert Herms, Kasumi Murai, Benjamin A. Hall, Philip H. Jones
Mar 18, 2021
Abstract: In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight...
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice.
Gabriel Piedrafita, Vasiliki Kostiou, Agnieszka Wabik, Bartomeu Colom, David Fernandez-Antoran, Albert Herms, Kasumi Murai, Benjamin A Hall, Philip H Jones
Apr 19, 2020
In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight into cell...
Published by: Nature Communications
Immersive Collaborative VR Application Design
Due to the recent COVID-19 pandemic, there has been a renewed interest in expanding the capabilities of remote collaboration tools. Studies show the importance of noticing peripheral cues, pointing to or manipulating real-world...
Published by: IGI Global Scientific Publishing
Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.
David Fernandez-Antoran, Gabriel Piedrafita, Kasumi Murai, Swee Hoe Ong, Albert Herms, Christian Frezza, Philip H Jones
Jul 23, 2019
As humans age, normal tissues, such as the esophageal epithelium, become a patchwork of mutant clones. Some mutations are under positive selection, conferring a competitive advantage over wild-type cells. We speculated that...
NFE2L2 TP53 cell competition cell tracing DIFFERENTIATION ionizing radiation Mitochondria Oxidative Stress Somatic mutation stem cell aging Animals antioxidants Cell Differentiation Cell Proliferation Cells Cultured Epithelial Cells esophagus Humans Mice Mice Transgenic Mutation NF-E2-Related Factor 2 Oxidation-Reduction Oxidative Stress RADIATION Ionizing Receptors Estrogen Tumor Suppressor Protein p53
The Lantern Vol. 16, No. 3, Spring 1948
R. C. Wentzel, Steven Arvanitis, W. E. Turner, Alvin Knepper, Nancy Twining, Jean Anne Schultz, Louis D. Stefan, William Keller, Bernice Harris, Helen Southall, Barbara Dietz, George Bock, Charles Wetzel
Jan 01, 0001
Not So Light Babba's Luck Winter Night God Hath Wrought Less Than Trivia What is Progress? Betrayal The Key Journey From a Star War and Peace Experiment in Prose Poetry Dawn Eternal Question My Gift ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Martin W. Witmer Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
GISwaps
This article describes how continuous GIS-MCDM problems are commonly managed by combining some weighting method based on pairwise comparisons of criteria with an aggregation method. The reliability of this approach may be...
Published by: IGI Global Scientific Publishing
Single and two-scale sharp-interface models for concrete carbonation—asymptotics and numerical approximation
We investigate the fast-reaction asymptotics for a one-dimensional reaction-diffusion
system describing the penetration of the carbonation reaction in concrete. The technique of matchedasymptotics
is used to show that...
system describing the penetration of the carbonation reaction in concrete. The technique of matchedasymptotics
is used to show that...
An Exploratory Mixed Method Study on H5P Videos and Video-Related Activities in a MOOC Environment
Martin Ebner, Stefan Thurner, Sandra Schön, Lisa Schirmbrand, Marco Tatschl, Theresa Teschl, Philipp Leitner
Jan 01, 2022
In this paper, an exploratory mixed-method study is presented examining the video-related behavior of participants of a massive open online course (MOOC; N=1.238). Firstly, detailed log-file analysis of six videos has been...
Published by: IGI Global Scientific Publishing
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