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The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models.
Mutations in PINK1 and Parkin/PRKN cause the degeneration of dopaminergic neurons in familial forms of Parkinson's disease but the precise pathogenic mechanisms are unknown. The PINK1/Parkin pathway has been described to play a...
Published by: Scientific reports
The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models
Abstract: Mutations in PINK1 and Parkin/PRKN cause the degeneration of dopaminergic neurons in familial forms of Parkinson’s disease but the precise pathogenic mechanisms are unknown. The PINK1/Parkin pathway has been described...
Generational Cohorts' Reactions
The purpose of this study is to better understand the consumer behaviour, analysing the impact of brand authenticity on two main behavioural outcomes. The research aims also at finding out the behavioural differences of each...
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging.
Glycosylation is a ubiquitous post-translational modification, present in over 50 % of the proteins in the human genome,1 with important roles in cell-cell communication and migration. Interest in glycome profiling has increased...
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Symen Ligthart, Carola Marzi, Stella Aslibekyan, Michael M Mendelson, Karen N Conneely, Toshiko Tanaka, Elena Colicino, Lindsay L Waite, Roby Joehanes, Weihua Guan, Jennifer A Brody, Cathy Elks, Riccardo Marioni, Min A Jhun, Golareh Agha, Jan Bressler, Cavin K Ward-Caviness, Brian H Chen, Tianxiao Huan, Kelly Bakulski, Elias L Salfati, WHI-EMPC Investigators, Giovanni Fiorito, CHARGE epigenetics of Coronary Heart Disease, Simone Wahl, Katharina Schramm, Jin Sha, Dena G Hernandez, Allan C Just, Jennifer A Smith, Nona Sotoodehnia, Luke C Pilling, James S Pankow, Phil S Tsao, Chunyu Liu, Wei Zhao, Simonetta Guarrera, Vasiliki J Michopoulos, Alicia K Smith, Marjolein J Peters, David Melzer, Pantel Vokonas, Myriam Fornage, Holger Prokisch, Joshua C Bis, Audrey Y Chu, Christian Herder, Harald Grallert, Chen Yao, Sonia Shah, Allan F McRae, Honghuang Lin, Steve Horvath, Daniele Fallin, Albert Hofman, Nicholas J Wareham, Kerri L Wiggins, Andrew P Feinberg, John M Starr, Peter M Visscher, Joanne M Murabito, Sharon LR Kardia, Devin M Absher, Elisabeth B Binder, Andrew B Singleton, Stefania Bandinelli, Annette Peters, Melanie Waldenberger, Giuseppe Matullo, Joel D Schwartz, Ellen W Demerath, André G Uitterlinden, Joyce BJ van Meurs, Oscar H Franco, Yii-Der Ida Chen, Daniel Levy, Stephen T Turner, Ian J Deary, Kerry J Ressler, Josée Dupuis, Luigi Ferrucci, Ken K Ong, Themistocles L Assimes, Eric Boerwinkle, Wolfgang Koenig, Donna K Arnett, Andrea A Baccarelli, Emelia J Benjamin, Abbas Dehghan
Feb 06, 2017
BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade...
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.
The phenotypic effect of some single nucleotide polymorphisms (SNPs) depends on their parental origin. We present a novel approach to detect parent-of-origin effects (POEs) in genome-wide genotype data of unrelated individuals....
Search for type-III seesaw heavy leptons in dilepton final states in pp collisions at √s=13TeV with the ATLAS detector
A search for the pair production of heavy leptons as predicted by the type-III seesaw mechanism is presented. The search uses proton-proton collision data at a centre-of-mass energy of 13 TeV, corresponding to 139 fb$^{-1}$...
Search for dark matter produced in association with a single top quark in √s=13 TeV pp collisions with the ATLAS detector
This paper presents a search for dark matter in the context of a two-Higgs-doublet model together with an additional pseudoscalar mediator, $a$, which decays into the dark-matter particles. Processes where the...
Measurement of isolated-photon plus two-jet production in pp collisions at √s = 13 TeV with the ATLAS detector
The dynamics of isolated-photon plus two-jet production in $pp$ collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset corresponding to an integrated luminosity of...
Measurement of the energy asymmetry in tt¯ j production at 13 TeV with the ATLAS experiment and interpretation in the SMEFT framework
A measurement of the energy asymmetry in jet-associated top-quark pair production is presented using 139 $\mathrm{fb}^{-1}$ of data collected by the ATLAS detector at the Large Hadron Collider during $pp$ collisions...
Observation of electroweak production of two jets in association with an isolated photon and missing transverse momentum, and search for a Higgs boson decaying into invisible particles at 13 TeV with the ATLAS detector
This paper presents a measurement of the electroweak production of two jets in association with a $Z\gamma$ pair, with the $Z$ boson decaying into two neutrinos. It also presents a search for invisible or partially...
Search for new phenomena in events with same-charge leptons and b-jets in pp collisions at √s=13 TeV with the ATLAS detector
A search for new phenomena in events with two same-charge leptons or three leptons and jets identified as originating from $b$-quarks in a data sample of 36.1 fb$^{-1}$ of $pp$ collisions at $\sqrt{s}= 13$ TeV recorded by the...
Search for a heavy Higgs boson decaying into a Z boson and another heavy Higgs boson in the ℓℓbb and ℓℓWW final states in pp collisions at √s=13 TeV with the ATLAS detector
A search for a heavy neutral Higgs boson, $A$, decaying into a $Z$ boson and another heavy Higgs boson, $H$, is performed using a data sample corresponding to an integrated luminosity of 139 fb$^{-1}$ from proton-proton...
Search for doubly and singly charged Higgs bosons decaying into vector bosons in multi-lepton final states with the ATLAS detector using proton-proton collisions at √s = 13 TeV
A search for charged Higgs bosons decaying into $W^\pm W^\pm$ or $W^\pm Z$ bosons is performed, involving experimental signatures with two leptons of the same charge, or three or four leptons with a variety of charge...
AtlFast3
The ATLAS experiment at the Large Hadron Collider has a broad physics programme ranging from precision measurements to direct searches for new particles and new interactions, requiring ever larger and ever more accurate datasets...

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