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Brain-Penetrating Histone Deacetylase Inhibitor RG2833 Reduces the Viability of Human Malignant Melanoma Cell Lines SK-MEL-5 and SK-MEL-28 in vitro
Lauren Green
Jan 01, 0001
Histone deacetylases (HDACs) play an important role in the epigenetic control of gene expression in both normal and cancer cells. Previous studies have demonstrated that pharmaceutical inhibition of HDACs can kill and/or...
Published by: Winthrop University
Brain-Penetrating Histone Deacetylase Inhibitor RG2833: A Potential Malignant Melanoma Growth Suppressor
Histone deacetylases (HDACs) play an important role in the epigenetic control of gene expression in both normal and cancer cells. Previous studies have demonstrated that pharmaceutical inhibition of HDACs can kill and/or...
Published by: Winthrop University
Personalized Mobile Learning and Course Recommendation System
Mobile-based learning provides new experience to the learners to learn anything from anywhere and anytime by using their portable or mobile device. Vast educational contents and also different media formats can be supported by...
Published by: IGI Global Scientific Publishing
Supernumerary kidneys
Peter Rehder, Rafael Rehwald, Julia M Böhm, Astrid E Grams, Alexander Loizides, Marco Pedrini, Jannik Stühmeier, Bernhard Glodny
Oct 16, 2020
BACKGROUND: A supernumerary kidney (SK) is an additional kidney with its own capsule and blood supply that is not fused with the ipsilateral kidney (IK). Because individual case reports indicate a high morbidity rate, the aim of...
Issue Information - TOC
SK Williams
Oct 18, 2018
Despite recent scholarship historians still know relatively little about the dynamics of the maintenance of illegitimate children under the old poor law. This article examines the affiliation system in Southwark and Lambeth...
A memory clinic v. traditional community mental health team service
Judy Sasha Rubinsztein, Marelna Janse van Rensburg, Zerak Al-Salihy, Deborah Girling, Louise Lafortune, Muralikrishnan Radhakrishnan, Carol Brayne
Aug 05, 2020
Aims and method To compare the cost and quality of a memory-clinic-based service (MCS) with a traditional community mental health team (CMHT) service. Using a retrospective case-note review, we studied two groups, each with 33...
MANUFACTURING MULTI-MATRIX COMPOSITES:
The formation of porosity is a major challenge in any composite manufacturing process, particularly in the absence of vacuum assistance. Highly localised injection of polymer matrix into regions of interest in a dry preform is a...
MANUFACTURING MULTI-MATRIX COMPOSITES:
The formation of porosity is a major challenge in any composite manufacturing process, particularly in the absence of vacuum assistance. Highly localised injection of polymer matrix into regions of interest in a dry preform is a...
Statistical Signal Properties of the Pressure-Reactivity Index (PRx)
Objectives: The pressure-reactivity index (PRx) is defined in terms of the moving correlation
coefficient between intracranial pressure (ICP) and mean arterial pressure (MAP) and is a
measure of cerebral autoregulation ability....
Does Knowledge Really Help?
Drawing on the self-determination theory, this study explored the effect of three kinds of low-carbon knowledge (LCB), including system knowledge (SK), action-related knowledge (AK), and effectiveness knowledge (EK), on college...
Published by: IGI Global Scientific Publishing
Black bone MRI with 3D reconstruction for the detection of skull fractures in children with suspected abusive head trauma.
Stephen F Kralik, Nucharin Supakul, Isaac C Wu, Gaspar Delso, Rupa Radhakrishnan, Chang Y Ho, Karen A Eley
Dec 11, 2019
PURPOSE: The purpose of this study was to determine the accuracy of "black bone" (BB) MRI for the detection of skull fractures in children with potential abusive head trauma. METHODS: A total of 34 pediatric patients were...
Evaluation of Diagnostic Performance of Machine Learning Algorithms to Classify the Fetal Heart Rate Baseline From Cardiotocograph
Cardiotocography (CTG) is the widely used cost-effective, non-invasive technique to monitor the fetal heart and mother’s uterine contraction pressure to assess the wellbeing of the fetus. The most important parameters of fetal...
Published by: IGI Global Scientific Publishing
LEAP-GWU-2015
As part of the LEAP-GWU-2015 exercise, a dynamic centrifuge test was conducted at the University of Cambridge on a 5° slope of medium dense Ottawa F-65 sand. The model preparation and saturation details are presented in this...
Dynamic and monotonic response of Monopile Foundations for Offshore wind turbines using centrifuge testing
Abstract The seismic response of monopile foundations is a growing area of research as the offshore wind industry expands worldwide, including in earthquake prone regions of the world. This paper...
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