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Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
catena-Poly triphenyltin(IV) -mu-phenylphosphinato-kappa(2)O
In the structure of the title coordination polymer, [Sn(C(6)H(5))(3)-(C(6)H(6)O(2)P)](n) or [PhP(H)O(2)Sn(IV)(Ph)(3)](n), the Sn(IV) atom is five-coordinate, with the SnC(3)O(2) framework in a trans trigonal-bipyramidal...
catena-Poly triphenyltin(IV) -mu-phenylphosphinato-kappa(2)O
In the structure of the title coordination polymer, [Sn(C(6)H(5))(3)-(C(6)H(6)O(2)P)](n) or [PhP(H)O(2)Sn(IV)(Ph)(3)](n), the Sn(IV) atom is five-coordinate, with the SnC(3)O(2) framework in a trans trigonal-bipyramidal...
Native Defects and their Doping Response in the Lithium Solid Electrolyte Li<sub>7</sub>La<sub>3</sub>Zr<sub>2</sub>O<sub>12</sub>
The Li-stuffed garnets Li xM 2M3′O 12 are promising Li-ion solid electrolytes with potential use in solid-state batteries. One strategy for optimizing ionic conductivities in these materials...
Conrad Russell, Richard Cust, and Andrew Thrush, eds. King James VI/I and His English Parliaments. New York
David L Smith
May 08, 2019
This book is a revised and extended version of the six Trevelyan Lectures that Conrad Russell delivered at Cambridge University in the Lent Term of 1995. Between then and his death in October 2004, Russell developed the lectures...
Native Defects and their Doping Response in the Lithium Solid Electrolyte Li<sub>7</sub>La<sub>3</sub>Zr<sub>2</sub>O<sub>12</sub>
The Li-stuffed garnets Li xM 2M3′O 12 are promising Li-ion solid electrolytes with potential use in solid-state batteries. One strategy for optimizing ionic conductivities in these materials...
Louis O. Kunkel, 1932
The Rockefeller University
Jan 01, 0001
Dr. L. O. Kunkel. Similarities Between the Diseases of the Vegetable Kingdom and Those of Man and Animals
Lecture delivered November 17th, 1932
Posted with permission
Published by: The Williams & Wilkins Company
Vacuum Ultraviolet Fourier-transform Spectroscopy of <sup>16</sup>O and <sup>18</sup>O
Abstract
A spectroscopic study of atomic oxygen (O i ) is performed using the Fourier-transform vacuum ultraviolet (VUV) spectrometer at the Dichroïsme Et...
Formyloxyacetoxyphenylmethane and 1,1-diacylals as versatile O-formylating and O-acylating reagents for alcohols
Formyloxyacetoxyphenylmethane, symmetric 1,1-diacylals and mixed 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as moisture stable O-formylating and O-acylating reagents for primary and secondary alcohols, allylic alcohols...
Formyloxyacetoxyphenylmethane and 1,1-diacylals as versatile O-formylating and O-acylating reagents for alcohols
Formyloxyacetoxyphenylmethane, symmetric 1,1-diacylals and mixed 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as moisture stable O-formylating and O-acylating reagents for primary and secondary alcohols, allylic alcohols...
Clinical and electrophysiological characterization of myokymia and neuromyotonia in Jack Russell Terriers.
AE Vanhaesebrouck, I Van Soens, L Poncelet, L Duchateau, S Bhatti, I Polis, S Diels, L Van Ham
Jul 03, 2019
BACKGROUND: Generalized myokymia and neuromyotonia (M/NM) in Jack Russell Terriers (JRTs) is related to peripheral nerve hyperexcitability syndrome in humans, a symptom complex resulting from diverse etiologies. OBJECTIVE...
Spectral Gap in Mean-Field O(n) -Model
Abstract We study the dependence of the spectral gap for the generator of the Ginzburg–Landau dynamics for all$$\mathcal...
O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli.
Connor Sharp, Christine Boinett, Amy Cain, Nicholas G Housden, Sandip Kumar, Keith Turner, Julian Parkhill, Colin Kleanthous
Aug 20, 2019
The outer membrane of Gram-negative bacteria presents a significant barrier for molecules entering the cell. Nevertheless, colicins, which are antimicrobial proteins secreted by Escherichia coli, can target other E. coli cells...
bacteriocins cell envelope enteric bacteria outer membrane Anti-Bacterial Agents Colicins DNA Transposable Elements Drug Resistance Bacterial Gene Silencing metabolism Microarray Analysis Microbial Sensitivity Tests Mutagenesis Insertional O Antigens Phenotype Sequence Analysis DNA Uropathogenic Escherichia coli
Ruthenium-catalyzed <i>O</i>- to S-alkyl migration
A practical ruthenium-catalyzed O- to S-alkyl migration affords structurally diverse thiooxazolidinones in excellent yields. Our studies suggest this catalytic transformation proceeds through a pseudoreversible radical...
Precise control of Cu$_2$O nanostructures and LED-assisted photocatalysis
We describe the synthesis and characterization of a high-efficiency visible light Cu$_2$O photocatalyst. Uniform cubic, octahedral and rhombic dodecahedral Cu$_2$O nanocrystals with a size of 300–600 nm were synthesized using a...
Short-Term Response of Cytosolic N O 3 - to Inorganic Carbon Increase in Posidonia oceanica Leaf Cells.
The concentration of CO2 in the atmosphere has increased over the past 200 years and is expected to continue rising in the next 50 years at a rate of 3 ppm·year-1. This increase has led to a decrease in seawater pH that has...
Short-Term Response of Cytosolic N O 3 − to Inorganic Carbon Increase in Posidonia oceanica Leaf Cells
The concentration of CO2 in the atmosphere has increased over the past 200 years and is expected to continue rising in the next 50 years at a rate of 3 ppm·year−1. This increase has led to a decrease in seawater pH that has...
Ruthenium-catalyzed <i>O</i>- to S-alkyl migration
A practical ruthenium-catalyzed O- to S-alkyl migration affords structurally diverse thiooxazolidinones in excellent yields. Our studies suggest this catalytic transformation proceeds through a pseudoreversible radical...
A systematic search for changing-look quasars in SDSS-II using difference spectra
Context. Changing-look quasars (CLQs) are active galactic nuclei (AGN) showing extreme variability that results in a transition from type 1 to type 2 AGN. The short timescales of these transitions present a challenge to the...
Improved bounds for the Erdős-Rogers function
The Erd\H{o}s-Rogers function $f_{s,t}$ measures how large a $K_s$-free
induced subgraph there must be in a $K_t$-free graph on $n$ vertices. While
good estimates for $f_{s,t}$ are known for some pairs $(s,t)$, notably...
Horizontally acquired divergent O-antigen contributes to escape from cross-immunity in the classical bordetellae
Sara E Hester, Jihye Park, Laura L Goodfield, Heather A Feaga, Andrew Preston, Eric T Harvill
Jan 01, 0001
Background:
Horizontal gene transfer (HGT) allows for rapid spread of genetic material between species, increasing genetic and phenotypic diversity. Although HGT contributes to adaptation and is widespread in many bacteria...
Horizontal gene transfer (HGT) allows for rapid spread of genetic material between species, increasing genetic and phenotypic diversity. Although HGT contributes to adaptation and is widespread in many bacteria...
The potential health impact of restricting less-healthy food and beverage advertising on UK television between 05.30 and 21.00 hours
Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition.
Erica Kintz, Christian Heiss, Ian Black, Nicholas Donohue, Naj Brown, Mark R Davies, Parastoo Azadi, Stephen Baker, Paul M Kaye, Marjan van der Woude
Apr 10, 2019
Salmonella enterica serovar Typhi is a human-restricted Gram-negative bacterial pathogen responsible for causing an estimated 27 million cases of typhoid fever annually, leading to 217,000 deaths, and current vaccines do not...
O-antigen Salmonella enterica LIPOPOLYSACCHARIDE phase variation serum resistance Animals Antibodies Bacterial Bacterial Proteins Base Sequence Disease Models Animal Female Gene Expression Regulation Bacterial Humans Immune Sera Immunization Methylation Mice O Antigens Operon Salmonella typhi Typhoid Fever
Very long O-antigen chains of Salmonella Paratyphi A inhibit inflammasome activation and pyroptotic cell death.
Elli Mylona, Julia Sanchez-Garrido, Trang Nguyen Hoang Thu, Sabina Dongol, Abhilasha Karkey, Stephen Baker, Avinash R Shenoy, Gad Frankel
Jan 22, 2021
Salmonella Paratyphi A (SPtA) remains one of the leading causes of enteric (typhoid) fever. Yet, despite the recent increased rate of isolation from patients in Asia, our understanding of its pathogenesis is incomplete. Here we...
FepE O-antigen Salmonella paratyphi A Salmonella typhimurium caspase-4 enteric fever Inflammasomes pyroptosis Bacterial Proteins Caspases HeLa Cells Humans Inflammasomes Intracellular Signaling Peptides and Proteins MACROPHAGES O Antigens Paratyphoid Fever Phosphate-Binding Proteins pyroptosis Salmonella paratyphi A THP-1 Cells Type III Secretion Systems Virulence Virulence Factors
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