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Results: 322
Liquid-Liquid Phase-Separated Systems from Reversible Gel-Sol Transition of Protein Microgels.
Yufan Xu, Runzhang Qi, Hongjia Zhu, Bing Li, Yi Shen, Georg Krainer, David Klenerman, Tuomas PJ Knowles
Apr 29, 2021
Liquid-liquid phase-separated biomolecular systems are increasingly recognized as key components in the intracellular milieu where they provide spatial organization to the cytoplasm and the nucleoplasm. The widespread use of...
Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels
Yufan Xu, Runzhang Qi, Hongjia Zhu, Bing Li, Yi Shen, Georg Krainer, David Klenerman, Tuomas P. J. Knowles
Jul 28, 2021
RESEARCH ARTICLE RESEARCH ARTICLES all‐aqueous emulsions biomolecular condensates elongated microgels gel–sol transition Gelatin macromolecular crowding liquid–liquid phase separation
Published by: Advanced Materials
Why is reporting quality improvement so hard? A qualitative study in perioperative care.
OBJECTIVES: Quality improvement (QI) may help to avert or mitigate the risks of suboptimal care, but it is often poorly reported in the healthcare literature. We aimed to identify the influences on reporting QI in the area of...
Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform.
Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform.
Determining the skills needed by frontline NHS staff to deliver quality improvement
BACKGROUND: Previous studies have detailed the technical, learning and soft skills healthcare staff deploy to deliver quality improvement (QI). However, research has mainly focused on management and leadership skills...
A Board Level Intervention to Develop Organisation-Wide Quality Improvement Strategies
Estela Capelas Barbosa, Lorelei Jones, Linda Pomeroy, Glenn Robert, Susan Burnett, Janet E Anderson, Steve Morris, Fulop Naomi
Aug 26, 2020
BACKGROUND: Hospital boards have statutory responsibility for upholding the quality of care in their organisations. International research on quality in hospitals resulted in a research-based guide to help senior hospital...
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
William E Arter, Runzhang Qi, Nadia A Erkamp, Georg Krainer, Kieran Didi, Timothy J Welsh, Julia Acker, Jonathan Nixon-Abell, Seema Qamar, Jordina Guillén-Boixet, Titus M Franzmann, David Kuster, Anthony A Hyman, Alexander Borodavka, Peter St George-Hyslop, Simon Alberti, Tuomas PJ Knowles
Jan 22, 2023
The assembly of biomolecules into condensates is a fundamental process underlying the organisation of the intracellular space and the regulation of many cellular functions. Mapping and characterising phase behaviour of...
The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus.
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
William E Arter, Runzhang Qi, Nadia A Erkamp, Georg Krainer, Kieran Didi, Timothy J Welsh, Julia Acker, Jonathan Nixon-Abell, Seema Qamar, Jordina Guillén-Boixet, Titus M Franzmann, David Kuster, Anthony A Hyman, Alexander Borodavka, Peter St George-Hyslop, Simon Alberti, Tuomas PJ Knowles
Dec 21, 2022
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Feb 15, 2020
BACKGROUND:The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Published by: BMC medical research methodology
Mapping outcomes in quality improvement and system design activities
BACKGROUND: Whether explicit or implicit, models of value are fundamental in quality improvement (QI) initiatives. They embody the desirability of the impact of interventions-with either foresight or hindsight. Increasingly...
Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses
Florian Geiger, Julia Acker, Guido Papa, Xinyu Wang, William E Arter, Kadi L Saar, Nadia A Erkamp, Runzhang Qi, Jack PK Bravo, Sebastian Strauss, Georg Krainer, Oscar R Burrone, Ralf Jungmann, Tuomas PJ Knowles, Hanna Engelke, Alexander Borodavka
Sep 15, 2021
EMBO23 EMBO40 article ARTICLES biomolecular condensates Microfluidics RNP granules viral genome assembly
Published by: The EMBO journal
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Jan 20, 2020
BACKGROUND: The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Dynamic Research on Youth Thought, Behavior, and Growth Law Based on Deep Learning Algorithm
Qi Fu
Apr 01, 2023
The growth and development of youth is related to the destiny of the country and the nation, and the cultivation of young people in the new era is of great significance. Youth is a special stage in life, and the ideological and...
Published by: IGI Global Scientific Publishing
A think-aloud method of investigating translanguaging strategies in learning Chinese characters
Asian scripts that are significantly different from Roman-derived alphabets usually impose difficulties in learning. Translanguaging has therefore been explored as a pedagogical tool for the language classroom, including...
Protecting the "Children"
Qi An
Apr 26, 2016
Progress towards understanding protein S-acylation
S-acylation, also known as S-palmitoylation or palmitoylation, is a reversible post-translational lipid modification in which long chain fatty acid, usually the 16-carbon palmitate, covalently attaches to a cysteine residue(s)...
Universal Arbitrage-free Estimation of State Price Density
Given the valuable information content of Arrow-Debreu prices, the recovery of a well behaved state price density is of considerable importance. However, this is a non-trivial task due to data limitation and the complex...
How Does User Social Network Improve Innovation Outcomes on a Virtual Innovation Platform?
Previous studies demonstrate that online interactive relations can help improve users' innovation outcomes, yet few studies have investigated how they influence user innovation. This paper builds a social network based on users'...
Published by: IGI Global Scientific Publishing
Governmental subsidy plan modeling and optimization for liquefied natural gas as fuel for maritime transportation
Environmental concerns are currently a major issue in the maritime transportation industry. A practical approach to implementing green maritime transportation is to adopt liquefied natural gas (LNG) as marine fuel. Government...
Process framework for innovation through tradition and its antecedents in rural heritage B&B
Purpose Innovation through tradition (ITT) is an increasingly important area of research particularly in the creative and cultural industries. The...
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