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A curated dataset of modern and ancient high-coverage shotgun human genomes.
Pierpaolo Maisano Delser, Eppie R Jones, Anahit Hovhannisyan, Lara Cassidy, Ron Pinhasi, Andrea Manica
Sep 05, 2021
Over the last few years, genome-wide data for a large number of ancient human samples have been collected. Whilst datasets of captured SNPs have been collated, high coverage shotgun genomes (which are relatively few but allow...
A curated dataset of modern and ancient high-coverage shotgun human genomes.
Pierpaolo Maisano Delser, Eppie R Jones, Anahit Hovhannisyan, Lara Cassidy, Ron Pinhasi, Andrea Manica
Sep 08, 2021
Over the last few years, genome-wide data for a large number of ancient human samples have been collected. Whilst datasets of captured SNPs have been collated, high coverage shotgun genomes (which are relatively few but allow...
Published by: Scientific data
A curated dataset of modern and ancient high-coverage shotgun human genomes
Pierpaolo Maisano Delser, Eppie R. Jones, Anahit Hovhannisyan, Lara Cassidy, Ron Pinhasi, Andrea Manica
Aug 11, 2021
Abstract: Over the last few years, genome-wide data for a large number of ancient human samples have been collected. Whilst datasets of captured SNPs have been collated, high coverage shotgun genomes (which are relatively few...
Climate shaped how Neolithic farmers and European hunter-gatherers interacted after a major slowdown from 6,100 BCE to 4,500 BCE.
Lia Betti, Robert M Beyer, Eppie R Jones, Anders Eriksson, Francesca Tassi, Veronika Siska, Michela Leonardi, Pierpaolo Maisano Delser, Lily K Bentley, Philip R Nigst, Jay T Stock, Ron Pinhasi, Andrea Manica
Jul 08, 2020
The Neolithic transition in Europe was driven by the rapid dispersal of Near Eastern farmers who, over a period of 3,500 years, brought food production to the furthest corners of the continent. However, this wave of expansion...
Upper Palaeolithic genomes reveal deep roots of modern Eurasians.
Eppie R Jones, Gloria Gonzalez-Fortes, Sarah Connell, Veronika Siska, Anders Eriksson, Rui Martiniano, Russell L McLaughlin, Marcos Gallego Llorente, Lara M Cassidy, Cristina Gamba, Tengiz Meshveliani, Ofer Bar-Yosef, Werner Müller, Anna Belfer-Cohen, Zinovi Matskevich, Nino Jakeli, Thomas FG Higham, Mathias Currat, David Lordkipanidze, Michael Hofreiter, Andrea Manica, Ron Pinhasi, Daniel G Bradley
Dec 04, 2015
Octane Appetite
Sarah Remmert, Steven Campbell, Roger Cracknell, Andrea Schuetze, Andrew Lewis, Karl Giles, Sam Akehurst, James Turner, Andrew Popplewell, Rishin Patel
Nov 30, 2014
Market demand for high performance gasoline vehicles and increasingly strict government emissions regulations are driving the development of highly downsized, boosted direct injection engines. The in-cylinder temperatures and...
Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago.
Veronika Siska, Eppie Ruth Jones, Sungwon Jeon, Youngjune Bhak, Hak-Min Kim, Yun Sung Cho, Hyunho Kim, Kyusang Lee, Elizaveta Veselovskaya, Tatiana Balueva, Marcos Gallego-Llorente, Michael Hofreiter, Daniel G Bradley, Anders Eriksson, Ron Pinhasi, Jong Bhak, Andrea Manica
Mar 14, 2017
East Asia Russian Far East ancient genetics human population genetics Neolithic Archaeology DNA Mitochondrial Asia Eastern Genome Human Genotype Guanine Nucleotide Exchange Factors Humans Phenotype Polymorphism Single Nucleotide principal component analysis Receptors Ectodysplasin Ubiquitin-Protein Ligases
Higher-order phosphatase–substrate contacts terminate the integrated stress response
Abstract: Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible...
Generic membrane spanning features endow IRE1α with responsiveness to membrane aberrancy
Animals CHO Cells Cell Membrane Cricetulus DNA-Binding Proteins Endoplasmic Reticulum Endoplasmic reticulum stress Endoribonucleases Lipids Membrane Proteins Membranes Mutation Palmitic Acid Protein Domains Protein Folding Protein Serine-Threonine Kinases Signal Transduction Transcription Factors Unfolded Protein Response eIF-2 Kinase
Upperclassmen Selected as Homecoming King and Queen
Winthrop University
Jan 01, 0001
Junior Ron Nelson and senior Sharetta Wynn were voted Homecoming King and Queen for Winthrop's Homecoming Fall 2009. They accepted their crowns Saturday, Nov. 14, during halftime of the men's basketball game against Limestone...
Published by: Winthrop University
Charlotte Orchestra to Play Winthrop Professor's Music
Winthrop University
Jan 01, 0001
The Charlotte Civic Orchestra will premiere "Torque," an original composition by faculty member Ron Parks, Nov. 12. The 3 p.m. concert will be held at University City Methodist Church.
Published by: Winthrop University
AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
The endoplasmic reticulum (ER)-localized Hsp70 chaperone BiP contributes to protein folding homeostasis by engaging unfolded client proteins in a process that is tightly coupled to ATP binding and hydrolysis. The inverse...
AMPylation BiP HSP70 J-proteins Biochemistry biophysics Endoplasmic Reticulum None structural biology Adenosine Monophosphate Adenosine Triphosphatases Adenosine Triphosphate Animals Cricetinae Crystallography X-Ray Endoplasmic Reticulum Chaperone BiP HEAT-SHOCK PROTEINS Hydrolysis Models Molecular Protein Binding Protein Conformation Protein Processing Post-Translational
Winthrop Faculty Members to be Featured in Providence Chamber Music Series
Winthrop University
Jan 01, 0001
The concert will feature a trio piece, "Things Get Out of Hand," composed by associate professor Ron Parks. The concert is 7 p.m. Oct 7 at Providence United Methodist Church in Charlotte. It is free and open to the public.
Published by: Winthrop University
Charlotte Symphony Orchestra to Perform Nov. 15 at Winthrop
Winthrop University
Jan 01, 0001
Guest conductor Chelsea Tipton will lead the 4 p.m. Nov. 15 concert in Byrnes Auditorium. Winthrop composer Ron Parks will perform one of his original pieces in a pre-concert at 3 p.m.
Published by: Winthrop University
How Do CIOs Become CEOs?
The role of information systems and technologies in any modern organization has become increasingly important. Concepts such as digital transformation and disruptive technologies have become the strategic directions for new and...
Published by: IGI Global Scientific Publishing
Pharmacological targeting of endoplasmic reticulum stress in disease.
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) leads to ER stress, resulting in activation of the unfolded protein response (UPR) that aims to restore protein homeostasis. However, the UPR also plays an...
Option Values in Sequential Auctions with Time-Varying Valuations
We investigate second-price sequential auctions of unit-demand bidders with time-variable valuations under complete information. We describe how a bidder figures willingness to pay by calculating option values, and show that...
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