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Results: 324
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.
David Reismann, Jonathan Stefanowski, Robert Günther, Asylkhan Rakhymzhan, Romano Matthys, Reto Nützi, Sandra Zehentmeier, Katharina Schmidt-Bleek, Georg Petkau, Hyun-Dong Chang, Sandra Naundorf, York Winter, Fritz Melchers, Georg Duda, Anja E Hauser, Raluca A Niesner
Jun 28, 2019
The bone marrow is a central organ of the immune system, which hosts complex interactions of bone and immune compartments critical for hematopoiesis, immunological memory, and bone regeneration. Although these processes take...
The Grizzly, March 3, 2016
Brian Thomas, Courtney A DuChene, Valerie Osborne, William DiCiurcio, Jay Farrell, Chenyu Yin, Sarah Hojsak, Tyler Arsenault, Maddie Mathay, Erin McKinney, Jordan Ostrum, Berett C Babrich, Hunter Gellman
Jan 01, 0001
UC Reveals Plans for Semester in Philly, New Coffee Shop Professor Romano Elected to National Book Critics Circle Business Students Win Competition in Philadelphia Relay for Life Gets Ready International Perspective...
Ursinus College Collegeville Pennsylvania newspaper Carlin Romano Philly X student housing CFA Challenge Relay for Life theater Caroline Gambone Carolyn Weigel career planning ping pong Sam Pope baseball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells
E 8 and the average size of the 3‐Selmer group of the Jacobian of a pointed genus‐2 curve
Abstract: We prove that the average size of the 3‐Selmer group of a genus‐2 curve with a marked Weierstrass point is 4. We accomplish this by studying rational and integral orbits in the representation associated to a stably Z /...
Published by: Proceedings of the London Mathematical Society
Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Ana Filipa Domingues, Rashmi Kulkarni, George Giotopoulos, Shikha Gupta, Laura Vinnenberg, Liliana Arede, Elena Foerner, Mitra Khalili, Rita Romano Adao, Ayona Johns, Shengjiang Tan, Keti Zeka, Brian J Huntly, Sudhakaran Prabakaran, Cristina Pina
Mar 24, 2020
Acute Myeloid Leukemia (AML) is an aggressive hematological malignancy with abnormal progenitor self-renewal and defective white blood cell differentiation. Its pathogenesis comprises subversion of transcriptional regulation...
KAT2A single-cell RNA seq acute myeloid leukaemia cancer biology Chromosomes epigenetics Gene Expression MOUSE transcriptional bursting transcriptional heterogeneity Animals Chromatin Histone Acetyltransferases Humans Leukemia Myeloid Acute Mice Mice Knockout Neoplastic Stem Cells Single-Cell Analysis Transcription Genetic Transcriptome
On the arithmetic of simple singularities of type <i>E</i>.
An ADE Dynkin diagram gives rise to a family of algebraic curves. In this paper, we use arithmetic
invariant theory to study the integral points of the curves associated to the exceptional diagrams E 6 , E 7 ,
E 8 . These curves...
Published by: Research in number theory
Towards supply chain collaboration in B2B pricing
Purpose – Research on business-to-business (B2B) pricing has been mainly focused on the supplier’s pricing process, thus adopting traditionally an internal perspective and perceiving pricing as a profit distribution parameter...
Towards supply chain collaboration in B2B pricing
Purpose – Research on business-to-business (B2B) pricing has been mainly focused on the supplier’s pricing process, thus adopting traditionally an internal perspective and perceiving pricing as a profit distribution parameter...
Establishing a Unified COVID-19 "Immunome"
Measuring GNSS ionospheric total electron content at Concordia, and application to L-band radiometers
In the framework of the project BIS - Bipolar Ionospheric Scintillation and Total Electron Content Monitoring, the ISACCO-DMC0 and ISACCO-DMC1 permanent monitoring stations were installed in 2008. The principal scope of the...
Measuring GNSS ionospheric total electron content at Concordia, and application to L-band radiometers
In the framework of the project BIS - Bipolar Ionospheric Scintillation and Total Electron Content Monitoring, the ISACCO-DMC0 and ISACCO-DMC1 permanent monitoring stations were installed in 2008. The principal scope of the...
Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer
Antonio Avallone, Biagio Pecori, Franco Bianco, Luigi Aloj, Fabiana Tatangelo, Carmela Romano, Vincenza Granata, Pietro Marone, Alessandra Leone, Gerardo Botti, Antonella Petrillo, Corradina Caracò, Vincenzo R Iaffaioli, Paolo Muto, Giovanni Romano, Pasquale Comella, Alfredo Budillon, Paolo Delrio
Jul 01, 2019
adjuvant chemotherapy Bevacizumab locally advanced rectal cancer preoperative chemo-radiotherapy vessel normalization Adult Aged Angiogenesis Inhibitors Antineoplastic Combined Chemotherapy Protocols Bevacizumab Chemoradiotherapy Adjuvant Disease Progression Disease-Free Survival Drug Administration Schedule Early Termination of Clinical Trials Female Fluorouracil Humans Italy Kaplan-Meier Estimate Leucovorin Magnetic Resonance Imaging Male Middle Aged Neoadjuvant Therapy Neoplasm Recurrence Local Organoplatinum Compounds Oxaliplatin Predictive Value of Tests Quinazolines Rectal Neoplasms Risk Factors Thiophenes Time Factors Treatment Outcome
Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer
G Nasti, MC Piccirillo, F Izzo, A Ottaiano, V Albino, P Delrio, C Romano, P Giordano, S Lastoria, C Caracò, E de Lutio di Castelguidone, R Palaia, G Daniele, L Aloj, G Romano, RV Iaffaioli
Dec 21, 2018
BACKGROUND: Preoperative treatment of resectable liver metastases from colorectal cancer (CRC) is a matter of debate. The aim of this study was to assess the feasibility and activity of bevacizumab plus FOLFIRI in this setting....
Adult Aged Antibodies Monoclonal Humanized Antineoplastic Combined Chemotherapy Protocols Bevacizumab camptothecin Chemotherapy Adjuvant Colorectal Neoplasms Disease-Free Survival Female Fluorouracil Humans Kaplan-Meier Estimate Leucovorin Liver Neoplasms Male Middle Aged Neoadjuvant Therapy Survival Rate
Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions.
Alexander CW Smith, Sietse Jonkman, Alexandra G Difeliceantonio, Richard M O'Connor, Soham Ghoshal, Michael F Romano, Barry J Everitt, Paul J Kenny
Nov 01, 2021
Comparatively little is known about how new instrumental actions are encoded in the brain. Using whole-brain c-Fos mapping, we show that neural activity is increased in the anterior dorsolateral striatum (aDLS) of mice that...
Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells.
James P Hewitson, Katie A West, Kylie R James, Gulab Fatima Rani, Nidhi Dey, Audrey Romano, Najmeeyah Brown, Sarah A Teichmann, Paul M Kaye, Dimitris Lagos
Jun 22, 2020
Despite extensive mapping of long noncoding RNAs in immune cells, their function in vivo remains poorly understood. In this study, we identify over 100 long noncoding RNAs that are differentially expressed within 24 h of Th1...
Immunological considerations and challenges for regenerative cellular therapies.
Sandra Petrus-Reurer, Marco Romano, Sarah Howlett, Joanne Louise Jones, Giovanna Lombardi, Kourosh Saeb-Parsy
Jun 16, 2021
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that integrate and function optimally. The capacity of pluripotent stem cells to produce unlimited numbers of differentiated cells is...
Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions.
Alexander C W Smith, Sietse Jonkman, Alexandra G Difeliceantonio, Richard M O'Connor, Soham Ghoshal, Michael F Romano, Barry J Everitt, Paul J Kenny
Sep 26, 2021
Comparatively little is known about how new instrumental actions are encoded in the brain. Using whole-brain c-Fos mapping, we show that neural activity is increased in the anterior dorsolateral striatum (aDLS) of mice that...
Corpus Striatum Neurons Animals Mice Inbred C57BL Mice Rats Rats Long-Evans Receptors Dopamine D1 Receptors Dopamine D2 Behavior Animal Conditioning Operant Male
Published by: Nature Communications
Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
Alexander C. W. Smith, Sietse Jonkman, Alexandra G. Difeliceantonio, Richard M. O’Connor, Soham Ghoshal, Michael F. Romano, Barry J. Everitt, Paul J. Kenny
Aug 26, 2021
Abstract: Comparatively little is known about how new instrumental actions are encoded in the brain. Using whole-brain c-Fos mapping, we show that neural activity is increased in the anterior dorsolateral striatum (aDLS) of mice...
Immunological considerations and challenges for regenerative cellular therapies
Sandra Petrus-Reurer, Marco Romano, Sarah Howlett, Joanne Louise Jones, Giovanna Lombardi, Kourosh Saeb-Parsy
Jun 25, 2021
Abstract: The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that integrate and function optimally. The capacity of pluripotent stem cells to produce unlimited numbers of differentiated...
Circulating megakaryocyte and platelet microvesicles correlate with response to ruxolitinib and distinct disease severity in patients with myelofibrosis.
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