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Syndicated Radio Personality Sheri Lynch '13 to Speak on Strength, Resilience
Winthrop University
Jan 01, 0001
Sheri Lynch, co-host of "The Bob and Sheri Show," will speak on strength and resilience during her Feb. 16 talk. Lynch, a two-time author and a graduate of Winthrop's Master of Social Work program, recently began sharing her...
Published by: Winthrop University
The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome.
Emma J Crosbie, Neil AJ Ryan, Mark J Arends, Tjalling Bosse, John Burn, Joanna M Cornes, Robin Crawford, Diana Eccles, Ian M Frayling, Sadaf Ghaem-Maghami, Heather Hampel, Noah D Kauff, Henry C Kitchener, Sarah J Kitson, Ranjit Manchanda, Raymond FT McMahon, Kevin J Monahan, Usha Menon, Pål Møller, Gabriela Möslein, Adam Rosenthal, Peter Sasieni, Mourad W Seif, Naveena Singh, Pauline Skarrott, Tristan M Snowsill, Robert Steele, Marc Tischkowitz, Manchester International Consensus Group, D Gareth Evans
Feb 07, 2020
PURPOSE: There are no internationally agreed upon clinical guidelines as to which women with gynecological cancer would benefit from Lynch syndrome screening or how best to manage the risk of gynecological cancer in women with...
Establishing the plane of symmetry for lumen formation and bilateral brain formation in the zebrafish neural rod.
The lumen of the zebrafish neural tube develops precisely at the midline of the solid neural rod primordium. This process depends on cell polarisation and cell rearrangements, both of which are manifest at the midline of the...
Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores
Nuclear pore complexes are constructed from a large number of different proteins, called collectively nucleoporins. One of these nucleoporins, p62, has an alpha-helical coiled-coil COOH-terminal rod domain linked to an...
Surface-induced nonlinearity enhancement in subwavelength rod waveguides
We develop a perturbative theory to describe optical propagation in subwavelength rod waveguides. In this approach, we account for loss and nonlinearity in the boundary conditions. A comparison to the traditional perturbative...
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
Jun 29, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
Surface-induced nonlinearity enhancement in subwavelength rod waveguides
We develop a perturbative theory to describe optical propagation in subwavelength rod waveguides. In this approach, we account for loss and nonlinearity in the boundary conditions. A comparison to the traditional perturbative...
Mirror-symmetric microtubule assembly and cell interactions drive lumen formation in the zebrafish neural rod.
Clare E Buckley, Xiaoyun Ren, Laura C Ward, Gemma C Girdler, Claudio Araya, Mary J Green, Brian S Clark, Brian A Link, Jonathan DW Clarke
Feb 01, 2019
By analysing the cellular and subcellular events that occur in the centre of the developing zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen formation. Cells from each side of the...
Animals Body Patterning Carrier Proteins Cell Communication Cell Division Cell Movement Cell Polarity Embryo Nonmammalian Green Fluorescent Proteins Luminescent Agents Microtubules Mutation Neural Tube Neurulation Nocodazole Protein Transport Recombinant Fusion Proteins Tubulin Modulators Zebrafish Zebrafish Proteins rab GTP-Binding Proteins
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
May 17, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, W Jason Cummings, Larry W Tjoelker, Teizo Fujita, Steven Sacks, Peter Garred, Peter Andrew, Robert B Sim, Peter J Lachmann, Russell Wallis, Nicholas Lynch, Wilhelm J Schwaeble
Aug 05, 2019
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...
Penetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing
D Gareth Evans, Emma Woodward, Elaine F Harkness, Anthony Howell, Inga Plaskocinska, Eamonn R Maher, Marc D Tischkowitz, Fiona Lalloo
Jul 02, 2018
PURPOSE: The identification of BRCA1, BRCA2 or mismatch repair (MMR) pathogenic gene variants in familial breast/ovarian/colorectal cancer families facilitates predictive genetic testing of at-risk relatives. However...
Lynch syndrome BRCA1 BRCA2 Penetrance pre-symptomatic Adult Aged BRCA1 Protein BRCA2 Protein Bayes Theorem Breast Neoplasms Colorectal Neoplasms Hereditary Nonpolyposis Female Genetic Predisposition to Disease Genetic Testing Humans Male Middle Aged MutL Protein Homolog 1 MutS Homolog 2 Protein Mutation Ovarian Neoplasms Penetrance Risk Assessment
Post-Doctoral Researcher's Conceptions of Research
This paper uses the analysis of metaphors to study the conceptions of research held by a sample of post-doctoral researchers at five Australian universities. It is based on an analysis of the metaphors the researchers use in...
Published by: University of Cambridge
Newly Identified Effects of Injector Nozzle Fouling in Diesel Engines
This paper describes newly identified effects of fouled injectors in diesel engines. As well as restricting and disrupting fuel flow into the combustion chamber, injector fouling has wider impacts on the engine, and these...
The Self in Research and Other Matters
Rod Pitcher
Apr 13, 2010
This study uses metaphor analysis to examine doctoral students’ conceptions obtained from their responses to an on-line survey. The conceptions examined were the conception of self in research, the conception of the PhD, the...
Published by: University of Cambridge
The Ursinus Weekly, November 4, 1929
"Personality" is theme of address by Dr. Lynch Entertainment course of year is announced Bears bow to Rutgers University in exciting and close game 19-13 Senior Hallowe'en ball is a memorable event Regional conference of "Y"...
Ursinus College Collegeville Pennsylvania newspaper Frederick Lynch Football field hockey Halloween debate team Miller H. Boeshore J. M. S. Isenberg YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Kinematic Behaviour of a Novel Pedicle Screw-Rod Fixation System for the Canine Lumbosacral Joint
Objective: To determine the biomechanical behaviour of a novel distraction-stabilization system, consisting of an intervertebral distraction bolt, polyaxial screws and connecting rods, in the canine lumbosacral spine.
Study...
Effects of off-plane deformation and biased bi-axial pre-strains on a planar contractile dielectric elastomer actuator
Dielectric elastomers are in a special class of electro-active polymers known for generating expansion in plane and contraction in thickness under voltage application. This paper advancesthe understanding of a planar contractile...
Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy
Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian Guo, Shiqin Zhu, Jin Guo, Ping Shi, Tony D. James, He Tian, Wei Hong Zhu
Jun 15, 2015
The rational design of high-performance fluorescent materials for cancer targeting in vivo is still challenging. A unique molecular design strategy is presented that involves tailoring aggregation-induced emission...
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