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A Radial Estimation-of-Distribution Algorithm for the Job-Shop Scheduling Problem
Ricardo Pérez-Rodríguez
Jan 01, 2022
The job-shop environment has been widely studied under different approaches. It is due to its practical characteristic that makes its research interesting. Therefore, the job-shop scheduling problem continues being attracted to...
Published by: IGI Global Scientific Publishing
A Physiological-Monitoring Electronic Platform for Cattle Grazing Systems
Ricardo Santos, Fabiana Alves, Patrik Bressan, Ricardo Aguiar, Wellington Santos, Rafael Costa
Jul 01, 2020
In this work, we present a non-invasive electronic platform for physiological data acquisition on cattle grazing systems. The platform can be used for dairy and beef cattle to continuously monitor physiological variables such as...
Published by: IGI Global Scientific Publishing
High order splitting methods for SDEs satisfying a commutativity condition
In this paper, we introduce a new simple approach to developing and establishing the convergence of splitting methods for a large class of stochastic differential equations (SDEs), including additive, diagonal, and scalar...
Diazaborines Are a Versatile Platform to Develop ROS-Responsive Antibody Drug Conjugates*.
João PM António, Joana Inês Carvalho, Ana S André, Joana NR Dias, Sandra I Aguiar, Hélio Faustino, Ricardo MRM Lopes, Luis F Veiros, Gonçalo JL Bernardes, Frederico A da Silva, Pedro MP Gois
Oct 08, 2021
Antibody-drug conjugates (ADCs) are a new class of therapeutics that combine the lethality of potent cytotoxic drugs with the targeting ability of antibodies to selectively deliver drugs to cancer cells. In this study we show...
Software and Systems Engineers in ICS Security
The introduction of Industry 4.0 and IIoT has enabled the interconnection of information technology (IT) and operational technology (OT) and exposed industrial control systems to cyber threats. Industrial cybersecurity requires...
Published by: IGI Global Scientific Publishing
Recommendation System for Sightseeing Tours
This research proposes a model of a recommendation system (RS) for tourist itineraries. The RS suggests tips of what to visit in a city, based on the available time, personal preferences, current geo-location, and the user's...
Business and Management Hospitality Travel and Tourism Management Hospitality Travel & Tourism Management
Published by: IGI Global Scientific Publishing
Self and Peer E-Assessment
In recent years, universities and other academic institutions have been performing collaborative learning to improve the students' skills, competencies, and learning outcomes. The problem-based learning approach is a learning...
Published by: IGI Global Scientific Publishing
A Study of Satisfaction and Loyalty for Continuance Intention of Mobile Wallet in India
How do satisfaction and loyalty drive Indian consumers' continued use of mobile financial applications? Do age, education, and income moderate these relationships? An analysis of 1,060 Indian participants revealed that consumer...
Published by: IGI Global Scientific Publishing
Price Strategy, Market Orientation, and Business Performance in the Hotel Industry
This study seeks to study the relationship between market orientation and business performance and to evaluate the mediating effect of adopting a low-price strategy in this relationship in the hotel industry. A sample from the...
Published by: IGI Global Scientific Publishing
Machine learning for target discovery in drug development.
Chemical probes Chemical proteomics Drug Discovery Machine Learning target identification Antineoplastic Agents Computer Simulation Drug Evaluation Preclinical Humans lipoxygenase Machine Learning Molecular Targeted Therapy Naphthoquinones Pentacyclic Triterpenes Proteomics Receptors Cannabinoid Sesquiterpenes Sesquiterpenes Guaiane Transient Receptor Potential Channels
The Effect of Reciprocity on Mobile Wallet Intention
The authors build on the literature on reciprocity by exploring a prevalent social and economic phenomenon in the Philippines where individuals with positive mobile phone balances can SMS loads to acquaintances. This practice is...
Published by: IGI Global Scientific Publishing
Antikörpergerichtete Therapien
In its various forms, cancer remains a leading cause of mortality and morbidity worldwide. Thus, it is widely accepted that finding innovative, life-changing drugs and therapeutic regimens is key for successful future cancer...
Protein-Protein Conjugates
The residues cysteine and lysine are the undisputed champions of bioconjugation chemistry. Targeting other amino acids has been touted as a potential way to improve the synthesis of protein–peptide and protein–protein conjugates...
Some Useful Sources
The literature on social protection in Latin America – and more specifically on Conditional Cash Transfers (CCTs) – is substantial and growing as, increasingly, more academics from around the world seem to be attracted to social...
Profiling IT Security and Interoperability in Brazilian Health Organisations From a Business Perspective
Rui Rijo, Ricardo Martinho, Adicinéia Oliveira, Domingos Alves, Zilma Reis, Cátia Santos-Pereira, Manuel Correia, Luís Antunes, Ricardo Cruz-Correia
Apr 01, 2020
The proliferation of electronic health (e-Health) initiatives in Brazil over the last 2 decades has resulted in a considerable fragmentation within health information technology (IT), with a strong political interference. The...
Published by: IGI Global Scientific Publishing
The Impact of Activity-Based Protein Profiling in Malaria Drug Discovery.
Activity-based protein profiling (ABPP) is an approach used at the interface of chemical biology and proteomics that uses small molecular probes to provide dynamic fingerprints of enzymatic activity in complex proteomes. Malaria...
High order splitting methods for SDEs satisfying a commutativity condition
In this paper, we introduce a new simple approach to developing and establishing the convergence of splitting methods for a large class of stochastic differential equations (SDEs), including additive, diagonal, and scalar...
Bioorthogonal Decaging Reactions for Targeted Drug Activation.
Bioorthogonal decaging reactions are highly selective transformations which involve the cleavage of a protecting group from a molecule of interest. Decaging reactions can be classified into subgroups depending on the nature of...
Development of Antibody-Directed Therapies
Less is more: The efficacy of antibody-drug conjugates (ADCs) for cancer therapy is traditionally associated with cleavable linkers for payload release. Evidence now suggests that simpler constructs without cleavable moieties...
Urban Endocrine Disruptors Targeting Breast Cancer Proteins.
Benzhydryl Compounds Binding Sites Breast Neoplasms Catalase Cytochrome P-450 CYP1A2 Databases Chemical Databases Protein Dioxins Endocrine Disruptors Environmental Pollutants Female Humans Molecular Dynamics Simulation Phenols Protein Binding Protein Structure Tertiary Recombinant Proteins Sex Hormone-Binding Globulin
Evidence-based design'evolving fast'
This article examines the background and history to, and advantages and disadvantages of, evidence-based design in healthcare.
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