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Results: 48
Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma.
Elisabete F Carapuça, Emilios Gemenetzidis, Christine Feig, Tashinga E Bapiro, Michael D Williams, Abigail S Wilson, Francesca R Delvecchio, Prabhu Arumugam, Richard P Grose, Nicholas R Lemoine, Frances M Richards, Hemant M Kocher
Apr 21, 2016
all-trans-retinoic acid Collagen Fibronectin Gemcitabine pancreatic stellate cells quiescence Adenocarcinoma Animals Antimetabolites Antineoplastic Apoptosis Carcinoma Pancreatic Ductal Cell Line Tumor Cell Proliferation Deoxycytidine Disease Models Animal Epithelial-Mesenchymal Transition Humans Mice Pancreatic Neoplasms Pancreatic Stellate Cells Signal Transduction Gemcitabine
Indirect learning
Some emerging-market firms have recently achieved substantial growth in developed markets despite having had little prior experience in these markets. What explains the performance of these firms? Building on the organizational...
Road Rage and Aggressive Driving Behaviour Detection in Usage-Based Insurance Using Machine Learning
Driving behaviour is a critical issue in modern transportation systems due to the increasing concerns about the safety of drivers, passengers, and road users. Machine learning models are capable of learning driving patterns from...
Published by: IGI Global Scientific Publishing
Innovation and entrepreneurship in India
In this paper, we use the term jugaad to describe the frugal, flexible, and inclusive approach to innovation and entrepreneurship emerging from India. We articulate why this method is appropriate within the Indian context and...
Frugal innovation
JC Prabhu
May 11, 2017
The global economy will face significant challenges over the next few decades. On the one hand, it must meet the needs of 7 billion consumers (growing to 9 billion by 2050), including the currently unmet basic needs of large...
Scaling up social businesses in developing markets
Most of the world's poor live in developing markets and face unmet needs in core areas such as education, health, energy, sanitation and financial services. This offers businesses a vast opportunity for growth as these economies...
Service innovation in the digital age
Over the last decade, there has been an increasing focus on service across socioeconomic sectors coupled with transformational developments in information and communication technologies (ICTs). Together these developments are...
Invitro evaluation of phytochemical profile and antidiabetic potential of Syzygium aromaticum Linn.
DIABETES consist of a group of diseases that are caused due to high level of glucose aka sugar in the blood, either due to the deficiency of insulin due to insufficient production or due to inappropriate response of the cells to...
Published by: IJHS Medical Association
The antecedents and consequences of affordable value innovations for emerging markets
Emerging markets offer tremendous growth opportunities for firms. While established multinational firms typically focus on premium segments in emerging markets, they often fail to leverage additional growth opportunities in...
Collagen fibre implant for tendon and ligament biological augmentation. In vivo study in an ovine model.
Davide Enea, Jessica Gwynne, Simon Kew, Meera Arumugam, Jennifer Shepherd, Roger Brooks, Siddhartha Ghose, Serena Best, Ruth Cameron, Neil Rushton
Apr 19, 2013
PURPOSE: Although most in vitro studies indicate that collagen is a suitable biomaterial for tendon and ligament tissue engineering, in vivo studies of implanted collagen for regeneration of these tissues are still lacking. The...
An Effective Multiple Linear Regression-Based Forecasting Model for Demand-Based Constructive Farming
Demand planning plays a very strategic role in improving the performance of every business, as the planning for a whole lot of other activities depends on the accuracy and validity of this exercise. The field of agriculture is...
Published by: IGI Global Scientific Publishing
Time Series for Forecasting Stock Market Prices Based on Sentiment Analysis of Social Media
This paper attempts to find a relation between the public perception of a company and its stock value price. Since social media is a very powerful tool used by a lot of people to voice their opinions on the performance of a...
Data Mining Computer Science and Information Technology Data Analysis and Statistics Business and Management Library and Information Science
Published by: IGI Global Scientific Publishing
Invitro evaluation of phytochemical profile and antidiabetic potential of Syzygium aromaticum Linn.
DIABETES consist of a group of diseases that are caused due to high level of glucose aka sugar in the blood, either due to the deficiency of insulin due to insufficient production or due to inappropriate response of the cells to...
Published by: IJHS Medical Association
Time Series for Forecasting Stock Market Prices Based on Sentiment Analysis of Social Media
This paper attempts to find a relation between the public perception of a company and its stock value price. Since social media is a very powerful tool used by a lot of people to voice their opinions on the performance of a...
Published by: IGI Global Scientific Publishing
Role of HRM Practices in Organization Performance
In recent years, HRM has received a lot of traction. Human resource management is essential for all types of enterprises. The bulk of research indicates that HRM and organizational performance have a positive link. Each...
Published by: IGI Global Scientific Publishing
The effect of particle size on the in vivo degradation of poly(d,l-lactide-co-glycolide)/α-tricalcium phosphate micro- and nanocomposites.
Sarah M Bennett, Meera Arumugam, Samuel Wilberforce, Davide Enea, Neil Rushton, Xiang C Zhang, Serena M Best, Ruth E Cameron, Roger A Brooks
Oct 21, 2016
degradation Nanocomposite Poly(d l-lactide-co-glycolide) Segmentation Tricalcium phosphate Animals Bone and Bones Calcium Phosphates Implants Experimental Lactic Acid Materials Testing Microspheres nanocomposites Particle Size Polyglycolic Acid Polylactic Acid-Polyglycolic Acid Copolymer Sheep X-Rays
Secured and Privacy-Based IDS for Healthcare Systems on E-Medical Data Using Machine Learning Approach
Sudhakar Sengan, Osamah Khalaf, Dilip Sharma, Abdulsattar Hamad, Vidya Sagar P., Arokia Jesu Prabhu L.
Jul 01, 2022
Existing methods use static path identifiers, making it easy for attackers to conduct DDoS flooding attacks. Create a system using Dynamic Secure aware Routing by Machine Learning (DAR-ML) to solve healthcare data. A DoS...
Published by: IGI Global Scientific Publishing
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.
Sundeep Chaitanya Vedithi, Sony Malhotra, Madhusmita Das, Sheela Daniel, Nanda Kishore, Anuja George, Shantha Arumugam, Lakshmi Rajan, Mannam Ebenezer, David B Ascher, Eddy Arnold, Tom L Blundell
Sep 27, 2018
The rpoB gene encodes the β subunit of RNA polymerase holoenzyme in Mycobacterium leprae (M. leprae). Missense mutations in the rpoB gene were identified as etiological factors for rifampin resistance in leprosy. In the present...
Adolescent Adult Bacterial Proteins DNA Bacterial DNA-Directed RNA Polymerases Drug Resistance Bacterial Female Humans india Leprostatic Agents Leprosy Male Microbial Sensitivity Tests Middle Aged Mutation Mycobacterium leprae Protein Binding Protein Stability Recurrence Rifampin Sequence Analysis DNA Structure-Activity Relationship Treatment Outcome Young Adult
Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cell-derived megakaryocytes
Jennifer H Shepherd, Daniel Howard, Amie K Waller, Holly Rebecca Foster, Annett Mueller, Thomas Moreau, Amanda L Evans, Meera Arumugam, Guénaëlle Bouët Chalon, Eleonora Vriend, Natalia Davidenko, Cedric Ghevaert, Serena M Best, Ruth E Cameron
Nov 08, 2018
Bioreactor Bone marrow model Collagen Depth straining Forward programming Human induced pluripotent stem cells interconnectivity Megakaryocytes Parallel flow membrane filter platelets scaffold architecture Settling zones shear flow Biocompatible Materials Bioreactors Blood Platelets Cell Culture Techniques Cells Cultured Collagen Equipment Design Humans Megakaryocytes Pluripotent Stem Cells Thrombopoiesis Tissue Scaffolds
Publisher Correction
Sundeep Chaitanya Vedithi, Sony Malhotra, Madhusmita Das, Sheela Daniel, Nanda Kishore, Anuja George, Shantha Arumugam, Lakshmi Rajan, Mannam Ebenezer, David B Ascher, Eddy Arnold, Tom L Blundell
Aug 05, 2020
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Published by: Sci Rep
How do the prevalence and relative risk of non-suicidal self-injury and suicidal thoughts vary across the population distribution of common mental distress (the p factor)? Observational analyses replicated in two independent UK cohorts of young people.
Ela Polek, Sharon AS Neufeld, Paul Wilkinson, Ian Goodyer, Michelle St Clair, Gita Prabhu, Ray Dolan, Edward T Bullmore, Peter Fonagy, Jan Stochl, Peter B Jones
Apr 03, 2020
child & adolescent psychiatry EPIDEMIOLOGY Public Health suicide & self-harm Adolescent Cohort Studies Female Health Surveys Humans Logistic Models Male Patient Dropouts prevalence psychological distress Reproducibility of Results risk Self-Injurious Behavior Suicidal Ideation United Kingdom Young Adult Suicide Prevention
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