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At War with Zola
Nicholas White
Jul 24, 2015
This lecture was presented at the 13th Annual Conference of the Society of Dix-Neuviémistes by Nicholas White (University of Cambridge). © 2015 Nicholas White.
Non-invasive technical investigation of english portrait miniatures attributed to Nicholas Hilliard and Isaac Oliver
This study presents the results of the technical investigation carried out on several English portrait miniatures painted in the 16th and 17th century by Nicholas Hilliard and Isaac Oliver, two of the most famous limners...
A Polygenic Risk Score to Predict Future Adult Short Stature Among Children.
Tianyuan Lu, Vincenzo Forgetta, Haoyu Wu, John RB Perry, Ken K Ong, Celia MT Greenwood, Nicholas J Timpson, Despoina Manousaki, J Brent Richards
Apr 26, 2021
CONTEXT: Adult height is highly heritable, yet no genetic predictor has demonstrated clinical utility compared to mid-parental height. OBJECTIVE: To develop a polygenic risk score for adult height and evaluate its clinical...
ALSPAC UK Biobank adult height prediction parental height polygenic risk score short stature Adult Aged Area Under Curve Body Height Child Child Preschool Female Genome-Wide Association Study Growth Disorders Humans Longitudinal Studies Male Middle Aged Predictive Value of Tests ROC Curve Risk Assessment Risk Factors United Kingdom White People
The New Capital of Spanish Language Literature
This translation was originally published as:
“The New Capital of Spanish Language Literature: The Best Seller.” New Spain New Literatures, by Maarten Steenmeijer. Eds. Luis Martín Estudillo and Nicholas Spadaccini. Vanderbilt...
Published by: Digital Commons @ Texas A&M University-San Antonio
The New Capital of Spanish Language Literature
This translation was originally published as:
“The New Capital of Spanish Language Literature: The Best Seller.” New Spain New Literatures, by Maarten Steenmeijer. Eds. Luis Martín Estudillo and Nicholas Spadaccini. Vanderbilt...
Published by: Digital Commons @ Texas A&M University-San Antonio
The New Capital of Spanish Language Literature
This translation was originally published as:
“The New Capital of Spanish Language Literature: The Best Seller.” New Spain New Literatures, by Maarten Steenmeijer. Eds. Luis Martín Estudillo and Nicholas Spadaccini. Vanderbilt...
Published by: Digital Commons @ Texas A&M University-San Antonio
An interactive genome browser of association results from the UK10K cohorts project.
Matthias Geihs, Ying Yan, Klaudia Walter, Jie Huang, Yasin Memari, Josine L Min, Daniel Mead, UK10K consortium, Tim J Hubbard, Nicholas J Timpson, Thomas A Down, Nicole Soranzo
Jun 25, 2018
UNLABELLED: High-throughput sequencing technologies survey genetic variation at genome scale and are increasingly used to study the contribution of rare and low-frequency genetic variants to human traits. As part of the Cohorts...
Review of the Book "Understanding Liberal Democracy: Essays in Political Philosophy"
Kelly Sorensen
Jan 01, 0001
[Excerpt] Nicholas Wolterstorff argues that public reason liberalism is a dead end, and defends instead what he takes to be a more defensible form of liberalism ("equal political voice liberalism"). His book is fresh and...
Nicholas Wolterstorff Terence Cuneo Oxford University Press political philosophy public reason liberalism Essays liberal democracy Rights equal political voice liberalism Ethics and Political Philosophy Philosophy
Published by: Ursinus College
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.
Ben Hollis, Felix R Day, Alexander S Busch, Deborah J Thompson, Ana Luiza G Soares, Paul R H J Timmers, Alex Kwong, Doug F Easton, Peter K Joshi, Nicholas J Timpson, Ken K Ong, John R B Perry
Apr 30, 2020
The timing of puberty is highly variable and is associated with long-term health outcomes. To date, understanding of the genetic control of puberty timing is based largely on studies in women. Here, we report a multi-trait...
Published by: Nature Communications
Effects of adiposity on the human plasma proteome
Lucy J Goudswaard, Joshua A Bell, David A Hughes, Laura J Corbin, Klaudia Walter, George Davey Smith, Nicole Soranzo, John Danesh, Emanuele Di Angelantonio, Willem H Ouwehand, Nicholas A Watkins, David J Roberts, Adam S Butterworth, Ingeborg Hers, Nicholas J Timpson
Sep 22, 2021
BACKGROUND: Variation in adiposity is associated with cardiometabolic disease outcomes, but mechanisms leading from this exposure to disease are unclear. This study aimed to estimate effects of body mass index (BMI) on an...
Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.
Despoina Manousaki, Ruth Mitchell, Tom Dudding, Simon Haworth, Adil Harroud, Vincenzo Forgetta, Rupal L Shah, Jian'an Luan, Claudia Langenberg, Nicholas J Timpson, J Brent Richards
Jan 14, 2021
We aimed to increase our understanding of the genetic determinants of vitamin D levels by undertaking a large-scale genome-wide association study (GWAS) of serum 25 hydroxyvitamin D (25OHD). To do so, we used imputed genotypes...
Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death
Mass and Heat Exchange in Rotating Compressor Cavities With Variable Cob Separation
Next generation aeroengines will operate at ever-increasing pressure ratios with smaller cores, where the control of blade-tip clearances across the flight cycle is an emerging design challenge. Such clearances are affected by...
Social Identity Theory in Sports Fandom Research
Nicholas Hirshon
May 08, 2020
Sports fans are known to engage in BIRGing, or basking in reflected glory after their team wins, and CORFing, cutting off reflected failure following a team loss. These phenomena are related to social identity theory, which...
Published by: IGI Global Scientific Publishing
A Model of Mass and Heat Transfer for Disc Temperature Prediction in Open Compressor Cavities
Accurate prediction of heat transfer in compressor cavities is crucial to the design of efficient and reliable aircraft engines. The heat transfer affects the thermal expansion of the compressor rotor and, in turn, the tip...
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR)
Veronika W Skrivankova, Rebecca C Richmond, Benjamin AR Woolf, Neil M Davies, Sonja A Swanson, Tyler J VanderWeele, Nicholas J Timpson, Julian PT Higgins, Niki Dimou, Claudia Langenberg, Elizabeth W Loder, Robert M Golub, Matthias Egger, George Davey Smith, J Brent Richards
Nov 08, 2021
Mendelian randomisation (MR) studies allow a better understanding of the causal effects of modifiable exposures on health outcomes, but the published evidence is often hampered by inadequate reporting. Reporting guidelines help...
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel.
Jie Huang, Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L Min, Petr Danecek, Giovanni Malerba, Elisabetta Trabetti, Hou-Feng Zheng, UK10K consortium, Giovanni Gambaro, J Brent Richards, Richard Durbin, Nicholas J Timpson, Jonathan Marchini, Nicole Soranzo
Jun 25, 2018
Imputing genotypes from reference panels created by whole-genome sequencing (WGS) provides a cost-effective strategy for augmenting the single-nucleotide polymorphism (SNP) content of genome-wide arrays. The UK10K Cohorts...
Early life programming in mice by maternal overnutrition
Animal models have been indispensable in elucidating the potential causative mechanisms underlying the effects of maternal diet on offspring health. Of these, the mouse has been widely used to model maternal overnutrition and/or...
Haploinsufficiency of NKX2-1 in Brain-Lung-Thyroid Syndrome with Additional Multiple Pituitary Dysfunction.
INTRODUCTION: Heterozygous mutations or haploinsufficiency of NKX2-1 are associated with the brain-lung-thyroid syndrome incorporating primary hypothyroidism, respiratory distress, and neurological disturbances. CASE...
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