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At War with Zola
Nicholas White
Jul 24, 2015
This lecture was presented at the 13th Annual Conference of the Society of Dix-Neuviémistes by Nicholas White (University of Cambridge). © 2015 Nicholas White.
R/BHC
BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...
Genomic contextualisation of ancient DNA molecular data from an Argentinian fifth pandemic Vibrio cholerae infection.
Specific lineages of serogroup O1 Vibrio cholerae are notorious for causing cholera pandemics, of which there have been seven since the 1800s. Much is known about the sixth pandemic (1899–1923) and the ongoing seventh pandemic...
Relationship Between Physical Fitness Variables and Reaction Time in eSports Gamers
eSports gaming requires quick and accurate reactions in response to complex visual stimuli for optimal performance. The purpose of this study was to examine the relationship between components of physical fitness and reaction...
Published by: IGI Global Scientific Publishing
gbpA and chiA genes are not uniformly distributed amongst diverse Vibrio cholerae.
Members of the bacterial genus Vibrio utilize chitin both as a metabolic substrate and a signal to activate natural competence. Vibrio cholerae is a bacterial enteric pathogen, sub-lineages of which can cause pandemic cholera....
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Alphonse R. Dochez, 1925
The Rockefeller University
Jan 01, 0001
Alphonse R. Dochez. Etiology of Scarlet Fever
Lecture delivered January 17th, 1925
Posted with permission
Published by: J.B. Lippincott Company
Florence R. Sabin, 1915
The Rockefeller University
Jan 01, 0001
Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System
Lecture delivered December 18th, 1915
Published by: J.B. Lippincott Company
Personality Antecedents of EWoM in Determining Online Customer Purchase Behavior
Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...
Published by: IGI Global Scientific Publishing
The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.
Ingmar B Schäfer, Geoffrey G Hesketh, Nicholas A Bright, Sally R Gray, Paul R Pryor, Philip R Evans, J Paul Luzio, David J Owen
May 11, 2020
SNAREs provide energy and specificity to membrane fusion events. Fusogenic trans-SNARE complexes are assembled from glutamine-contributing SNAREs (Q-SNAREs) embedded in one membrane and an arginine-contributing SNARE (R-SNARE)...
Determining antimicrobial susceptibility in Salmonella enterica serovar Typhimurium through whole genome sequencing
Nana Mensah, Yue Tang, Shaun Cawthraw, Manal AbuOun, Jackie Fenner, Nicholas R Thomson, Alison E Mather, Liljana Petrovska-Holmes
Jul 01, 2020
BACKGROUND: UK public health organisations perform routine antimicrobial susceptibility tests (ASTs) to characterise the potential for antimicrobial resistance in Salmonella enterica serovars. Genetic determinants of these...
Agar dilution Antimicrobial susceptibility tests Broth microdilution Disk diffusion Salmonella enterica serovar typhimurium whole genome sequencing Anti-Bacterial Agents Drug Resistance Multiple Bacterial Genome Bacterial Genotype Humans Microbial Sensitivity Tests Phenotype Salmonella enterica Salmonella typhimurium Sensitivity and Specificity Serogroup whole genome sequencing
Non-invasive technical investigation of english portrait miniatures attributed to Nicholas Hilliard and Isaac Oliver
This study presents the results of the technical investigation carried out on several English portrait miniatures painted in the 16th and 17th century by Nicholas Hilliard and Isaac Oliver, two of the most famous limners...
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R Barnes, Jonathan Beesley, Otto Sanchez, Hal K Berman, Grant W Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C Antoniou, Cheryl H Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
Feb 15, 2021
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Genomic Analysis of Salmonella enterica Serovar Typhimurium from Wild Passerines in England and Wales.
Alison E Mather, Becki Lawson, Elizabeth de Pinna, Paul Wigley, Julian Parkhill, Nicholas R Thomson, Andrew J Page, Mark A Holmes, Gavin K Paterson
Oct 25, 2016
Animals Animals Wild Bacteriophage Typing Bird Diseases Cats Disease Reservoirs Drug Resistance Bacterial England Genome Bacterial Genomics Humans Multilocus Sequence Typing Phylogeny Plasmids Polymorphism Single Nucleotide Salmonella Infections Salmonella Infections Animal Salmonella typhimurium Serogroup Serotyping Sparrows Virulence Wales
Using R and Bioconductor for proteomics data analysis.
This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features...
PlasmidTron
Andrew J Page, Alexander Wailan, Yan Shao, Kim Judge, Gordon Dougan, Elizabeth J Klemm, Nicholas R Thomson, Jacqueline A Keane
Feb 16, 2019
Increasingly rich metadata are now being linked to samples that have been whole-genome sequenced. However, much of this information is ignored. This is because linking this metadata to genes, or regions of the genome, usually...
Antimicrobial resistance De novo assembly Genome-Wide Association Study mobile genetic elements Plasmids DNA Copy Number Variations Genetic Association Studies Genome Bacterial Genotype High-Throughput Nucleotide Sequencing Klebsiella pneumoniae Microbial Sensitivity Tests Phenotype Phylogeny Plasmids Salmonella enterica Sequence Analysis DNA
A farewell to <i>R</i>
The time-dependent reproduction number, Rt, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...
Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens.
Whole-genome sequencing (WGS) has been vital for revealing the rapid temporal and spatial evolution of antimicrobial resistance (AMR) in bacterial pathogens. Some antimicrobial-resistant pathogens have outpaced us, with...
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD.
Yannick Marcon, Tom Bishop, Demetris Avraam, Xavier Escriba-Montagut, Patricia Ryser-Welch, Stuart Wheater, Paul Burton, Juan R González
Apr 09, 2021
Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and share...
Contrasting patterns of longitudinal population dynamics and antimicrobial resistance mechanisms in two priority bacterial pathogens over 7 years in a single center.
Matthew J Ellington, Eva Heinz, Alexander M Wailan, Matthew J Dorman, Marcus de Goffau, Amy K Cain, Sonal P Henson, Nicholas Gleadall, Christine J Boinett, Gordon Dougan, Nicholas M Brown, Neil Woodford, Julian Parkhill, M Estée Török, Sharon J Peacock, Nicholas R Thomson
Sep 06, 2019
BACKGROUND: Two of the most important pathogens contributing to the global rise in antimicrobial resistance (AMR) are Klebsiella pneumoniae and Enterobacter cloacae. Despite this, most of our knowledge about the changing...
Explanatory Adequacy in Phonology
Eric Russell Webb
Aug 01, 2013
This work reexamines phonological variation particular to the /R/ of convergent French, departing from the hypothesis that a deductive approach to this question can offer explanatory advantages. In contrast to data-driven...
Published by: Atlantic Provinces Linguistic Association
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