BACKGROUND: Observational studies have shown that attentional bias for smoking-related cues is associated with increased craving and relapse. Laboratory experiments have shown that manipulating attentional bias may change...
BACKGROUND: Ambulatory and/or home monitoring are recommended in the UK and the US for the diagnosis of hypertension but little is known about their acceptability. AIM: To determine the acceptability of different methods of...
Pt(II) di-ynes and poly-ynes incorporating 5,5’- and 6,6’-disubstituted 2,2’-bipyridines were prepared following conventional Sonogashira and Hagihara dehydrohalogenation reaction protocols. Using Pt(II) dimers and polymers as a...
Pt(II) di-ynes and poly-ynes incorporating 5,5’- and 6,6’-disubstituted 2,2’-bipyridines were prepared following conventional Sonogashira and Hagihara dehydrohalogenation reaction protocols. Using Pt(II) dimers and polymers as a...
BACKGROUND: Hypertension is a major risk factor for cardiovascular disease and prevalence varies by ethnic group. The diagnosis and management of blood pressure are informed by guidelines largely based on data from white...
Hetero-aryl incorporated acetylide-functionalized pyridinyl ligands (L1-6) with the general formula Py-C≡C-Ar (Py = pyridine and Ar = thiophene-2-yl, 2,2'-bithiophene]-5-yl, 2,2':5',2''-terthiophene]-5-yl...
Delivering in water has recently become popular, and more hospitals now offer water birth. However, water birth is still considered an alternative birthing method. Water birth refers to childbirth, usually human, that occurs in...
Hetero-aryl incorporated acetylide-functionalized pyridinyl ligands (L1-6) with the general formula Py-C≡C-Ar (Py = pyridine and Ar = thiophene-2-yl, 2,2'-bithiophene]-5-yl, 2,2':5',2''-terthiophene]-5-yl...
Delivering in water has recently become popular, and more hospitals now offer water birth. However, water birth is still considered an alternative birthing method. Water birth refers to childbirth, usually human, that occurs in...
Molecular imaging of cardiovascular disease is a powerful clinical and experimental approach that can inform our understanding of atherosclerosis biology. Complementing cross-sectional imaging techniques that provide detailed...
INTRODUCTION: The role of positron emission tomography (PET)/computed tomography (CT) in the determination of inflammation in arterial disease is not well defined. This can provide information about arterial wall inflammation in...
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
The chromatin state is finely tuned to regulate function and specificity for transcription factors such as oestrogen receptor alpha (ER), which contributes to cell growth in breast cancer. ER transcriptional potential is...
Fetal/perinatal hypoxia is one of the most common causes of perinatal morbidity and mortality and is frequently accompannied by vascular dysfunction. However, the mechanisms involved have not been fully delineated. We...
BACKGROUND: Throughout the last decade, tuberculosis (TB) treatment success has not surpassed 90%, the global target. The impact of mobile health interventions (MHIs) on TB treatment outcomes is unknown, especially in low- and...
Ubiquitous environments are not fixed in time. Entities are constantly evolving; they are dynamic. Ubiquitous applications therefore have a strong need to adapt during their execution and react to the context changes, and...
The Human Immunodeficiency Virus Type-1 (HIV-1) is the causative agent of the Acquired Immune Deficiency Syndrome (AIDS). Combination antiviral therapy has proven to be particularly effective at suppressing viral replication...