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Clinical implications of germline mutations in breast cancer genes
BACKGROUND: The identification of new hereditary breast cancer genes is an area of highly active research. In 2015, two independent studies provided initial evidence for a novel breast cancer susceptibility gene, RECQL, a DNA...
Recording Preserves Signature Sound of Famed Organ
Winthrop University
Jan 01, 0001
Quick Facts
Ramsay was awarded First Prize at the Amsterdam International Organ Competition in 2014. At 17 years old, he was awarded the organ scholarship at King's College, Cambridge, where he served under the direction of...
Published by: Winthrop University
Trading interactions
Purpose - The purpose of this paper is to explore the nature of buyers' attitudes towards the partial consensus surrounding the benefits of buyer-supplier cooperation - the relational exchange perspective.
...
Psychological Network Analysis of General Self-Efficacy in High vs. Low Resilient Functioning Healthy Adults.
Katja Schueler, Jessica Fritz, Lena Dorfschmidt, Anne-Laura van Harmelen, Eike Stroemer, Michèle Wessa
Dec 15, 2021
Resilience to stress has gained increasing interest by researchers from the field of mental health and illness and some recent studies have investigated resilience from a network perspective. General self-efficacy constitutes an...
MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa
Miao Ma, Margaux Lustig, Michèle Salem, Dominique Mengin-Lecreulx, Gilles Phan, Isabelle Broutin
May 21, 2021
One of the major families of membrane proteins found in prokaryote genome corresponds to the transporters. Among them, the resistance-nodulation-cell division (RND) transporters are highly studied, as being responsible for one...
MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa.
Miao Ma, Margaux Lustig, Michèle Salem, Dominique Mengin-Lecreulx, Gilles Phan, Isabelle Broutin
Jul 07, 2021
One of the major families of membrane proteins found in prokaryote genome corresponds to the transporters. Among them, the resistance-nodulation-cell division (RND) transporters are highly studied, as being responsible for one...
Pseudomonas efflux pump assembly membrane Peptidoglycan resistance Bacterial Outer Membrane Proteins Cell Wall Drug Resistance Bacterial Escherichia coli Membrane Transport Proteins Models Molecular Peptidoglycan Protein Interaction Domains and Motifs Protein Stability Protein Structure Quaternary Pseudomonas aeruginosa
Trading interactions
Purpose - The purpose of this paper is to explore the nature of buyers' attitudes towards the partial consensus surrounding the benefits of buyer-supplier cooperation - the relational exchange perspective.
...
A self-assembly toolbox for thiophene-based conjugated polyelectrolytes
Judith E Houston, Michèle Chevrier, Marie-Sousai Appavou, Stephen M King, Sébastien Clément, Rachel C Evans
Apr 25, 2018
Targeted control of the aggregation, morphology and optical properties of conjugated polymers is critical for the development of high performance optoelectronic devices. Here, self-assembly approaches are used to strategically...
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
Michèle Romanos, Guillaume Allio, Myriam Roussigné, Léa Combres, Nathalie Escalas, Cathy Soula, François Médevielle, Benjamin Steventon, Ariane Trescases, Bertrand Bénazéraf
Oct 05, 2021
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know little about its biological functions. By studying progenitors of the posterior region of bird...
Genetics of Degenerative Cervical Myelopathy
Daniel H. Pope, Benjamin M. Davies, Oliver D. Mowforth, A. Ramsay Bowden, Mark R. N. Kotter
Jan 21, 2020
Degenerative cervical myelopathy (DCM) is estimated to be the most common cause of adult spinal cord impairment. Evidence that is suggestive of a genetic basis to DCM has been increasing over the last decade. A systematic search...
Expanding the light absorption of poly(3-hexylthiophene) by end-functionalization with π-extended porphyrins.
Michèle Chevrier, Sébastien Richeter, Olivier Coulembier, Mathieu Surin, Ahmad Mehdi, Roberto Lazzaroni, Rachel C Evans, Philippe Dubois, Sébastien Clément
Jul 03, 2018
Poly(3-hexylthiophene)s end-functionalized with π-extended porphyrins have been synthesized in a one-pot procedure. The polymers show a broad absorption profile extending to 700 nm and a fibrillar microstructure, which can be...
Associations Between Maternal Prenatal C-Reactive Protein and Risk Factors for Psychosis in Adolescent Offspring
Hugh Ramsay, Heljä-Marja Surcel, Lassi Björnholm, Martta Kerkelä, Golam M Khandaker, Juha Veijola
Sep 24, 2020
Prenatal infection is associated with brain structural and functional abnormalities and may increase the risk for psychosis through a direct effect on neurodevelopment. Various infections may exert their effect through a...
‘Waste the waist’
Fiona Bridget Gillison, Colin Greaves, Afroditi Stathi, Rosemary Ramsay, P Bennett, Gordon Taylor, Margaret Francis, Roger Chandler
May 01, 2012
Objectives. To identify an evidence-based intervention to promote changes in diet and physical activity and adapt it for a UK primary care setting for people with high cardiovascular risk.
Design. A three-stage...
High-depth African genomes inform human migration and health.
Ananyo Choudhury, Shaun Aron, Laura R Botigué, Dhriti Sengupta, Gerrit Botha, Taoufik Bensellak, Gordon Wells, Judit Kumuthini, Daniel Shriner, Yasmina J Fakim, Anisah W Ghoorah, Eileen Dareng, Trust Odia, Oluwadamilare Falola, Ezekiel Adebiyi, Scott Hazelhurst, Gaston Mazandu, Oscar A Nyangiri, Mamana Mbiyavanga, Alia Benkahla, Samar K Kassim, Nicola Mulder, Sally N Adebamowo, Emile R Chimusa, Donna Muzny, Ginger Metcalf, Richard A Gibbs, TrypanoGEN Research Group, Charles Rotimi, Michèle Ramsay, H3Africa Consortium, Adebowale A Adeyemo, Zané Lombard, Neil A Hanchard
Dec 24, 2020
The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the genetic diversity among African individuals has...
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny.
Michèle Romanos, Guillaume Allio, Myriam Roussigné, Léa Combres, Nathalie Escalas, Cathy Soula, François Médevielle, Benjamin Steventon, Ariane Trescases, Bertrand Bénazéraf
Nov 05, 2021
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know little about its biological functions. By studying progenitors of the posterior region of bird...
bird embryos cell motility developmental biology Heterogeneity mathematical modeling Morphogenesis neuromesodermal progenitors Animals Cell Differentiation Cell Lineage Embryo Nonmammalian Fetal Proteins Gene Expression Gene Expression Regulation Developmental Quail SOXB1 Transcription Factors T-Box Domain Proteins
Participatory Action Research on School Culture and Student Mental Health
Greta Kaluzeviciute, Tricia Jessiman, Anne–Marie Burn, Tamsin Ford, Emma Geijer–Simpson, Judi Kidger, Mark Limmer, Sheena E. Ramsay, Liam Spencer
Oct 26, 2021
Background: Young people spend a large proportion of their time in school, which presents both risk and protective factors for their mental health. A supportive school culture can promote and protect good mental health by...
Monitoring the hepatitis C epidemic in England and evaluating intervention scale-up using routinely collected data.
Ross J Harris, Helen E Harris, Sema Mandal, Mary Ramsay, Peter Vickerman, Matthew Hickman, Daniela De Angelis
Mar 14, 2019
In England, 160 000 individuals were estimated to be chronically infected with hepatitis C virus (HCV) in 2005 and the burden of severe HCV-related liver disease has increased steadily for the past 15 years. Direct-acting...
back calculation direct-acting antiviral treatment disease burden people who inject drugs surveillance data Adolescent Adult Aged Aged 80 and over Antiviral Agents Child Child Preschool England Female Hepatitis C Chronic Humans Incidence Infant Infant Newborn Male Middle Aged Models Statistical prevalence Surveys and Questionnaires Young Adult
Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.
Michèle Brocard, Valentina Iadevaia, Philipp Klein, Belinda Hall, Glenys Lewis, Jia Lu, James Burke, Margaret M Willcocks, Roy Parker, Ian G Goodfellow, Alessia Ruggieri, Nicolas Locker
Jan 31, 2020
Viral infections impose major stress on the host cell. In response, stress pathways can rapidly deploy defence mechanisms by shutting off the protein synthesis machinery and triggering the accumulation of mRNAs into stress...
Animals Caliciviridae Infections Cell Line Cytoplasmic Granules DNA Helicases Eukaryotic Initiation Factor-2 Humans Mice Mice Inbred C57BL Norovirus Poly-ADP-Ribose Binding Proteins Protein Biosynthesis RAW 264.7 Cells RNA RNA Helicases RNA Recognition Motif Proteins Signal Transduction Virus Replication
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