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Results: 1593
Laminin Levels Regulate Tissue Migration and Anterior-Posterior Polarity during Egg Morphogenesis in Drosophila.
María C Díaz de la Loza, Alfonsa Díaz-Torres, Federico Zurita, Alicia E Rosales-Nieves, Emad Moeendarbary, Kristian Franze, María D Martín-Bermudo, Acaimo González-Reyes
Mar 28, 2018
Basement membranes (BMs) are specialized extracellular matrices required for tissue organization and organ formation. We study the role of laminin and its integrin receptor in the regulation of tissue migration during Drosophila...
Efficiency and accuracy of visual search develop at different rates from early childhood through early adulthood
Abstract: Most studies of visual search across the life span have focused on classic feature and conjunction searches in which observers search for a fixed, simple shape target among relatively homogeneous distractors over a...
Integration and Open Access System Based on Semantic Technologies
The aim of this work is the development of an information system that, by integrating data from different sources and applying semantic technologies, makes it possible to publish and share with society the scientific production...
Published by: IGI Global Scientific Publishing
Efficiency and accuracy of visual search develop at different rates from early childhood through early adulthood
Abstract: Most studies of visual search across the life span have focused on classic feature and conjunction searches in which observers search for a fixed, simple shape target among relatively homogeneous distractors over a...
An improved technique for the assessment of venom-induced haemorrhage in a murine model.
Timothy P Jenkins, Andrés Sánchez, Álvaro Segura, Mariángela Vargas, María Herrera, Trenton K Stewart, Guillermo León, José María Gutiérrez
May 16, 2018
Haemorrhage is a common clinical manifestation in envenomings caused by bites from snakes of the family Viperidae. Therefore, knowing the haemorrhagic potential of venoms and the capacity of antivenoms to neutralise this effect...
Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma
Esperanza M. Algarín, Dalia Quwaider, Francisco J. Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Elena Vuelta, Montserrat Martín-Sánchez, Laura San-Segundo, Lorena González-Méndez, Norma C. Gutiérrez, Ramón García-Sanz, Teresa Paíno, Javier De Las Rivas, Enrique M. Ocio, Mercedes Garayoa
Mar 05, 2021
BH3-mimetics targeting anti-apoptotic proteins such as MCL-1 (S63845) or BCL-2 (venetoclax) are currently being evaluated as effective therapies for the treatment of multiple myeloma (MM). Interleukin 6, produced by mesenchymal...
Zebrafish Models of Autosomal Dominant Ataxias
Ana Quelle-Regaldie, Daniel Sobrido-Cameán, Antón Barreiro-Iglesias, María Jesús Sobrido, Laura Sánchez
Feb 20, 2021
Hereditary dominant ataxias are a heterogeneous group of neurodegenerative conditions causing cerebellar dysfunction and characterized by progressive motor incoordination. Despite many efforts put into the study of these...
Deciphering Master Gene Regulators and Associated Networks of Human Mesenchymal Stromal Cells.
Elena Sánchez-Luis, Andrea Joaquín-García, Francisco J Campos-Laborie, Fermín Sánchez-Guijo, Javier De Las Rivas
Jun 22, 2020
Mesenchymal Stromal Cells (MSC) are multipotent cells characterized by self-renewal, multilineage differentiation, and immunomodulatory properties. To obtain a gene regulatory profile of human MSCs, we generated a compendium of...
Zebrafish Models of Autosomal Recessive Ataxias.
Ana Quelle-Regaldie, Daniel Sobrido-Cameán, Antón Barreiro-Iglesias, María Jesús Sobrido, Laura Sánchez
Jun 28, 2021
Autosomal recessive ataxias are much less well studied than autosomal dominant ataxias and there are no clearly defined systems to classify them. Autosomal recessive ataxias, which are characterized by neuronal and multisystemic...
Characterization of a Fetal Liver Cell Population Endowed with Long-Term Multiorgan Endothelial Reconstitution Potential.
Ana Cañete, Valentine Comaills, Isabel Prados, Ana María Castro, Seddik Hammad, Patricia Ybot-Gonzalez, Ernesto Bockamp, Jan G Hengstler, Bertie Gottgens, María José Sánchez
Oct 04, 2016
Endothelial reconstitution Fetal liver Hematopoietic progenitors Newborn transplantation Progenitor cells Animals Antigens CD blood vessels Cadherins Cell Aggregation Cell Line Endothelial Cells Extracellular Matrix Proteins Fetus Hematopoiesis Leukocyte Common Antigens Liver Mice Organ Specificity T-Cell Acute Lymphocytic Leukemia Protein 1
Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma.
Esperanza M Algarín, Dalia Quwaider, Francisco J Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Elena Vuelta, Montserrat Martín-Sánchez, Laura San-Segundo, Lorena González-Méndez, Norma C Gutiérrez, Ramón García-Sanz, Teresa Paíno, Javier De Las Rivas, Enrique M Ocio, Mercedes Garayoa
May 17, 2021
BH3-mimetics targeting anti-apoptotic proteins such as MCL-1 (S63845) or BCL-2 (venetoclax) are currently being evaluated as effective therapies for the treatment of multiple myeloma (MM). Interleukin 6, produced by mesenchymal...
A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype.
Ana Quelle-Regaldie, Mónica Folgueira, Julián Yáñez, Daniel Sobrido-Cameán, Anabel Alba-González, Antón Barreiro-Iglesias, María-Jesús Sobrido, Laura Sánchez
Aug 01, 2022
NOP56 belongs to a C/D box small nucleolar ribonucleoprotein complex that is in charge of cleavage and modification of precursor ribosomal RNAs and assembly of the 60S ribosomal subunit. An intronic expansion in NOP56 gene...
Zebrafish Models of Autosomal Dominant Ataxias.
Ana Quelle-Regaldie, Daniel Sobrido-Cameán, Antón Barreiro-Iglesias, María Jesús Sobrido, Laura Sánchez
May 03, 2021
Hereditary dominant ataxias are a heterogeneous group of neurodegenerative conditions causing cerebellar dysfunction and characterized by progressive motor incoordination. Despite many efforts put into the study of these...
Zebrafish Models of Autosomal Recessive Ataxias
Ana Quelle-Regaldie, Daniel Sobrido-Cameán, Antón Barreiro-Iglesias, María Jesús Sobrido, Laura Sánchez
Apr 09, 2021
Autosomal recessive ataxias are much less well studied than autosomal dominant ataxias and there are no clearly defined systems to classify them. Autosomal recessive ataxias, which are characterized by neuronal and multisystemic...
Complement component 3 as biomarker of disease activity and cardiometabolic risk factor in rheumatoid arthritis and spondyloarthritis.
Iván Arias de la Rosa, Pilar Font, Alejandro Escudero-Contreras, María Dolores López-Montilla, Carlos Pérez-Sánchez, María Carmen Ábalos-Aguilera, Lourdes Ladehesa-Pineda, Alejandro Ibáñez-Costa, Carmen Torres-Granados, Yolanda Jimenez-Gomez, Alejandra Patiño-Trives, María Luque-Tévar, María Carmen Castro-Villegas, Jerusalem Calvo-Gutiérrez, Rafaela Ortega-Castro, Chary López-Pedrera, Eduardo Collantes-Estévez, Nuria Barbarroja
Oct 23, 2020
Direct measurement of lensing amplification in Abell S1063 using a strongly lensed high redshift HII galaxy
<i>In vitro</i> conditions for performance evaluation of products for intravascular administration
Currently, there are no compendial in vitro release tests specifically indicated for parenteral formulations. Consideration of biorelevant and clinically relevant test media represents a valuable approach for the development...
Integrin-Mediated Adhesion in the Unicellular Holozoan Capsaspora owczarzaki.
Helena Parra-Acero, Matija Harcet, Núria Sánchez-Pons, Elena Casacuberta, Nicholas H Brown, Omaya Dudin, Iñaki Ruiz-Trillo
Sep 15, 2020
In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors...
Patenting and business outcomes for cleantech startups funded by the Advanced Research Projects Agency-Energy
Innovation to reduce the cost of clean technologies has large environmental and societal benefits. Governments can play an important role in helping cleantech startups innovate and overcome risks involved in technology...
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