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Cover Image for Interview with Nancy Hinson Cox View Article
Interview with Nancy Hinson Cox
Nancy Hinson Cox
Jan 01, 0001
In her July 16, 1974 interview with Ann Yarborough Evans, Nancy Cox recalls Winthrop customs from 1930-1934. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program.
Home economics teaching Dorm Life Rules and Regulations daisy chain blue line McLaurin Lancaster Swimming religion Oral History
Published by: Winthrop University
Cover Image for Cancer Markers Selection Using Network-Based Cox Regression View Article
Cancer Markers Selection Using Network-Based Cox Regression
Antonella Iuliano, Annalisa Occhipinti, Claudia Angelini, Italia De Feis, Pietro Lió
Mar 20, 2019
International initiatives such as the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) are collecting multiple datasets at different genome-scales with the aim of identifying novel cancer...
Cox model Cancer Gene Expression high-dimensionality Network regularization survival
Cover Image for APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. View Article
APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.
Alba Signes, Raffaele Cerutti, Anna S Dickson, Cristiane Benincá, Elizabeth C Hinchy, Daniele Ghezzi, Rosalba Carrozzo, Enrico Bertini, Michael P Murphy, James A Nathan, Carlo Viscomi, Erika Fernandez-Vizarra, Massimo Zeviani
Dec 21, 2018
Loss-of-function mutations in APOPT1, a gene exclusively found in higher eukaryotes, cause a characteristic type of cavitating leukoencephalopathy associated with mitochondrial cytochrome c oxidase (COX) deficiency. Although the...
APOPT1‐COA8 cytochrome c oxidase mitochondrial encephalopathy proteasome–ubiquitin system Reactive Oxygen Species Animals Apoptosis Regulatory Proteins Cells Cultured Electron Transport Complex IV Genetic Complementation Test Humans Mice Mice Knockout Mitochondrial Proteins Protein Multimerization Reactive Oxygen Species Unfolded Protein Response
Cover Image for Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation. View Article
Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation.
Dan Jackson, Ian R White, Shaun Seaman, Hannah Evans, Kathy Baisley, James Carpenter
Jun 14, 2018
The Cox proportional hazards model is frequently used in medical statistics. The standard methods for fitting this model rely on the assumption of independent censoring. Although this is sometimes plausible, we often wish to...
Schoenfeld residuals bootstrapping informative censoring Multiple imputation sensitivity analysis Survival Analysis Acyclovir Adolescent Adult Antiviral Agents Bias Biometry Computer Simulation Female HIV Infections Herpes Genitalis Herpesvirus 2 Human Humans Monte Carlo Method Proportional Hazards Models Randomized Controlled Trials as Topic Regression Analysis Tanzania Young Adult
Cover Image for SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies. View Article
SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies.
MacGregor Cox, Thomas P Peacock, William T Harvey, Joseph Hughes, Derek W Wright, COVID-19 Genomics UK (COG-UK) Consortium, Brian J Willett, Emma Thomson, Ravindra K Gupta, Sharon J Peacock, David L Robertson, Alessandro M Carabelli
Nov 28, 2022
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19 and are especially important in high-risk individuals where vaccination is not an option. Given the importance of understanding the...
Humans SARS-CoV-2 Antibodies Monoclonal covid-19 Amino Acid Substitution Antibodies Neutralizing Epitopes Antibodies Viral
Cover Image for Going off grid View Article
Going off grid
D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue
Mar 01, 2016
This paper introduces a new method for performing computational inference on log-Gaussian Cox processes. The likelihood is approximated directly by making novel use of a continuously specified Gaussian random field. We show that...
Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation
Cover Image for On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale View Article
On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale
Alexander M. G. Cox, Jan Obłój
Aug 01, 2015
We study the joint laws of a continuous, uniformly integrable martingale, its maximum, and its minimum. In particular, we give explicit martingale inequalities which provide upper and lower bounds on the joint exit probabilities...
Cover Image for Going off grid View Article
Going off grid
D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue
Mar 01, 2016
This paper introduces a new method for performing computational inference on log-Gaussian Cox processes. The likelihood is approximated directly by making novel use of a continuously specified Gaussian random field. We show that...
Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation
Cover Image for On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale View Article
On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale
Alexander M. G. Cox, Jan Obłój
Aug 01, 2015
We study the joint laws of a continuous, uniformly integrable martingale, its maximum, and its minimum. In particular, we give explicit martingale inequalities which provide upper and lower bounds on the joint exit probabilities...
Cover Image for Martingale optimal transport with stopping View Article
Martingale optimal transport with stopping
Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev
Jan 01, 0001

We solve the martingale optimal transport problem for cost functionals represented by optimal stopping problems. The measure-valued martingale approach developed in [A. M. G. Cox and S. Källblad, SIAM J. Control Optim., 55...

math.PR 60G40 93E20 91A10 91A60 60G07
Cover Image for Martingale optimal transport with stopping View Article
Martingale optimal transport with stopping
Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev
Jan 01, 0001

We solve the martingale optimal transport problem for cost functionals represented by optimal stopping problems. The measure-valued martingale approach developed in [A. M. G. Cox and S. Källblad, SIAM J. Control Optim., 55...

math.PR 60G40 93E20 91A10 91A60 60G07
Cover Image for Robust Hedging of Options on a Leveraged Exchange Traded Fund View Article
Robust Hedging of Options on a Leveraged Exchange Traded Fund
Alexander M. G. Cox, Sam M. Kinsley
Feb 01, 2019

A leveraged exchange traded fund (LETF) is an exchange traded fund that uses financial derivatives to amplify the price changes of a basket of goods. In this paper, we consider the robust hedging of European options on a...

Leveraged exchange traded fund monotonicity principle Optimal Skorokhod embedding problem Robust pricing and Hedging
Cover Image for Robust Hedging of Options on a Leveraged Exchange Traded Fund View Article
Robust Hedging of Options on a Leveraged Exchange Traded Fund
Alexander M. G. Cox, Sam M. Kinsley
Feb 01, 2019

A leveraged exchange traded fund (LETF) is an exchange traded fund that uses financial derivatives to amplify the price changes of a basket of goods. In this paper, we consider the robust hedging of European options on a...

Leveraged exchange traded fund monotonicity principle Optimal Skorokhod embedding problem Robust pricing and Hedging
Cover Image for Discretisation and Duality of Optimal Skorokhod Embedding Problems View Article
Discretisation and Duality of Optimal Skorokhod Embedding Problems
Alexander M. G. Cox, Sam M. Kinsley
Jul 31, 2018

We prove a strong duality result for a linear programming problem which has the interpretation of being a discretised optimal Skorokhod embedding problem, and we recover this continuous time problem as a limit of the discrete...

Cover Image for Discretisation and Duality of Optimal Skorokhod Embedding Problems View Article
Discretisation and Duality of Optimal Skorokhod Embedding Problems
Alexander M. G. Cox, Sam M. Kinsley
Jul 31, 2018

We prove a strong duality result for a linear programming problem which has the interpretation of being a discretised optimal Skorokhod embedding problem, and we recover this continuous time problem as a limit of the discrete...

Cover Image for Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines. View Article
Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.
Agata Tarczykowska, Niklas Engström, Darja Dobermann, Jonathan Powell, Nathalie Scheers
Apr 17, 2023
We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell...
Iron IL-6 IGF1R COX-2 amphiregulin IFNGR1 ferric pyrophosphate Cell Line Humans Adenocarcinoma Iron Compounds Ferric Compounds Salts Edetic Acid Interleukin-6 Iron Chelating Agents Signal Transduction STAT Transcription Factors Cyclooxygenase 2 Janus Kinases Biomarkers
Published by: International journal of molecular sciences
Cover Image for Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer. View Article
Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer.
Derek W Wright, William T Harvey, Joseph Hughes, MacGregor Cox, Thomas P Peacock, Rachel Colquhoun, Ben Jackson, Richard Orton, Morten Nielsen, Nienyun Sharon Hsu, COVID-19 Genomics UK (COG-UK) Consortium, Ewan M Harrison, Thushan I de Silva, Andrew Rambaut, Sharon J Peacock, David L Robertson, Alessandro M Carabelli
Jun 07, 2022
covid-19 SARS-CoV-2 amino acid replacements Antibody Escape antigenic variation evasion evolution FITNESS Mutation Protein Structure resistance spike variants of concern Virus
Cover Image for The geometry of multi-marginal Skorokhod Embedding View Article
The geometry of multi-marginal Skorokhod Embedding
Mathias Beiglboeck, Alexander Cox, Martin Huesmann
Apr 30, 2020

The Skorokhod Embedding Problem is one of the classical problems in the theory of stochastic processes, with applications in many different fields [cf. the surveys (Hobson in: Paris-Princeton lectures on mathematical finance...

math.PR q-fin.PR 60G42 60G44 91G20
Cover Image for The geometry of multi-marginal Skorokhod Embedding View Article
The geometry of multi-marginal Skorokhod Embedding
Mathias Beiglboeck, Alexander Cox, Martin Huesmann
Apr 30, 2020

The Skorokhod Embedding Problem is one of the classical problems in the theory of stochastic processes, with applications in many different fields [cf. the surveys (Hobson in: Paris-Princeton lectures on mathematical finance...

math.PR q-fin.PR 60G42 60G44 91G20
Cover Image for Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses. View Article
Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses.
Jue-Sheng Ong, Eske M Derks, Mikael Eriksson, Jiyuan An, Liang-Dar Hwang, Douglas F Easton, Paul P Pharoah, Andrew Berchuck, Linda E Kelemen, Keitaro Matsuo, Georgia Chenevix-Trench, Per Hall, Stig E Bojesen, Penelope M Webb, Stuart MacGregor
Sep 23, 2020
Alcohol consumption is correlated positively with risk for breast cancer in observational studies, but observational studies are subject to reverse causation and confounding. The association with epithelial ovarian cancer (EOC)...
Mendelian randomization Alcohol intake Breast Cancer causal inference ovarian cancer Alcohol Drinking Breast Neoplasms Carcinoma Ovarian Epithelial Causality Cohort Studies Female Humans Mendelian Randomization Analysis Odds Ratio Ovarian Neoplasms
Cover Image for Toward the stereochemical assignment and synthesis of hemicalide View Article
Toward the stereochemical assignment and synthesis of hemicalide
Callum I MacGregor, Bing Yuan Han, Jonathan M Goodman, Ian Paterson
Mar 08, 2016
0305 Organic Chemistry
Cover Image for Semantics, syntax or neither? A case for resolution in the interpretation of N500 and P600 responses to harmonic incongruities. View Article
Semantics, syntax or neither? A case for resolution in the interpretation of N500 and P600 responses to harmonic incongruities.
Cara R Featherstone, Catriona M Morrison, Mitch G Waterman, Lucy J MacGregor
Nov 21, 2019
The processing of notes and chords which are harmonically incongruous with their context has been shown to elicit two distinct late ERP effects. These effects strongly resemble two effects associated with the processing of...
Acoustic Stimulation Auditory Perception Electroencephalography Evoked Potentials Auditory Female Humans Male music Parietal Lobe semantics Young Adult
Cover Image for An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei. View Article
An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei.
Mathieu Cayla, Lindsay McDonald, Paula MacGregor, Keith Matthews
Jun 15, 2020
The sleeping sickness parasite, Trypanosoma brucei, uses quorum sensing (QS) to balance proliferation and transmission potential in the mammal bloodstream. A signal transduction cascade regulates this process, a component of...
DYRK Trypanosoma DIFFERENTIATION Gene Expression infectious disease microbiology None PARASITE Protein Kinase Amino Acid Motifs Cell Differentiation Gene Expression Regulation Developmental Protein Serine-Threonine Kinases Protein-Tyrosine Kinases Quorum Sensing Signal Transduction Transcription Genetic Trypanosoma brucei brucei
Cover Image for Well-Defined Heterobimetallic Reactivity at Unsupported Ruthenium-Indium Bonds View Article
Well-Defined Heterobimetallic Reactivity at Unsupported Ruthenium-Indium Bonds
Ian Riddlestone, Nasir Rajabi, Stuart MacGregor, Mary Mahon, Michael Whittlesey
Feb 01, 2018

The hydride complex [Ru(IPr) 2(CO)H][BAr F 4], 1, reacts with InMe 3 with loss of CH 4 to form [Ru(IPr) 2(CO)(InMe)(Me)][BAr F 4], 4...

density functional calculations Gallium heterometallic complexes Indium Ruthenium
Cover Image for Information can explain the dynamics of group order in animal collective behaviour. View Article
Information can explain the dynamics of group order in animal collective behaviour.
Hannah EA MacGregor, James E Herbert-Read, Christos C Ioannou
Jul 27, 2020
Animal groups vary in their collective order (or state), forming disordered swarms to highly polarized groups. One explanation for this variation is that individuals face differential benefits or costs depending on the group's...
Algorithms Animals Behavior Animal Group Processes Models Biological Population Dynamics Smegmamorpha Social Behavior

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