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Results: 249
Assessment of common infections and incident dementia using UK primary and secondary care data
Rutendo Muzambi, Krishnan Bhaskaran, Liam Smeeth, Carol Brayne, Nish Chaturvedi, Charlotte Warren-Gash
Jul 02, 2021
BACKGROUND: Common infections have been associated with dementia risk; however, evidence is scarce. We aimed to investigate the association between common infections and dementia in adults (≥65 years) in a UK population-based...
Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations
Elizabeth Moore, Lia Chatzidiakou, Roderic L Jones, Liam Smeeth, Sean Beevers, Frank J Kelly, Jennifer K Quint, Benjamin Barratt
Jul 29, 2016
COPD Exacerbation Monitor pollution Adult Aged Aged 80 and over Air Pollutants Air Pollution Cohort Studies Data Collection Electronic Health Records Environmental Exposure Environmental Monitoring Female Humans London Male Middle Aged Models Biological Pulmonary Disease Chronic Obstructive Research Design Self Report Severity of Illness Index
Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records.
Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers
Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records.
Propensity score analysis with partially observed covariates
Clémence Leyrat, Shaun R Seaman, Ian R White, Ian Douglas, Liam Smeeth, Joseph Kim, Matthieu Resche-Rigon, James R Carpenter, Elizabeth J Williamson
Jun 13, 2018
Missing covariates Rubin’s rules chained equations inverse probability of treatment weighting missingness pattern Bias Data Interpretation Statistical Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Models Statistical Observational Studies as Topic Pneumonia Probability Propensity Score Treatment Outcome
Socioeconomic determinants of leprosy new case detection in the 100 Million Brazilian Cohort
Joilda Silva Nery, Anna Ramond, Julia Moreira Pescarini, André Alves, Agostino Strina, Maria Yury Ichihara, Maria Lucia Fernandes Penna, Liam Smeeth, Laura C Rodrigues, Mauricio L Barreto, Elizabeth B Brickley, Gerson Oliveira Penna
Sep 18, 2019
BACKGROUND: Although leprosy is recognised as a disease of poverty, there is little evidence on the specific socioeconomic factors associated with disease risk. To inform targeted strategies for disease elimination, we...
Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes
Patrick Bidulka, Edouard L Fu, Clémence Leyrat, Fotini Kalogirou, Katherine SL McAllister, Edward J Kingdon, Kathryn E Mansfield, Masao Iwagami, Liam Smeeth, Catherine M Clase, Krishnan Bhaskaran, Merel van Diepen, Juan-Jesus Carrero, Dorothea Nitsch, Laurie A Tomlinson
Jul 29, 2021
BACKGROUND: The safety of restarting angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARB) after acute kidney injury (AKI) is unclear. There is concern that previous users do not restart...
Acute Kidney Injury Angiotensin II receptor blocker (ARB) Angiotensin-converting enzyme inhibitor (ACEI) Heart Failure Acute Kidney Injury Adolescent Adult Aged Aged 80 and over Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Cohort Studies Female Humans Male Middle Aged Proportional Hazards Models Sweden United Kingdom Young Adult
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research.
Jennifer K Quint, Elisabeth Moore, Adam Lewis, Maimoona Hashmi, Kirin Sultana, Mark Wright, Liam Smeeth, Lia Chatzidiakou, Roderic Jones, Sean Beevers, Sefki Kolozali, Frank Kelly, Benjamin Barratt
Sep 20, 2018
Databases of electronic health records (EHR) are not only a valuable source of data for health research but have also recently been used as a medium through which potential study participants can be screened, located and...
Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes
Patrick Bidulka, Edouard L. Fu, Clémence Leyrat, Fotini Kalogirou, Katherine S. L. McAllister, Edward J. Kingdon, Kathryn E. Mansfield, Masao Iwagami, Liam Smeeth, Catherine M. Clase, Krishnan Bhaskaran, Merel van Diepen, Juan-Jesus Carrero, Dorothea Nitsch, Laurie A. Tomlinson
Jul 29, 2020
Abstract: Background: The safety of restarting angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARB) after acute kidney injury (AKI) is unclear. There is concern that previous users do not...
Geographic and socioeconomic factors associated with leprosy treatment default
Kaio Vinicius Freitas de Andrade, Joilda Silva Nery, Julia Moreira Pescarini, Anna Ramond, Carlos Antônio de Souza Teles Santos, Maria Yury Ichihara, Maria Lucia Fernandes Penna, Elizabeth B Brickley, Laura C Rodrigues, Liam Smeeth, Mauricio L Barreto, Susan Martins Pereira, Gerson Oliveira Penna
Oct 22, 2019
BACKGROUND: Although leprosy is largely curable with multidrug therapy, incomplete treatment limits therapeutic effectiveness and is an important obstacle to disease control. To inform efforts to improve treatment completion...
Interpretation of the evidence for the efficacy and safety of statin therapy.
Rory Collins, Christina Reith, Jonathan Emberson, Jane Armitage, Colin Baigent, Lisa Blackwell, Roger Blumenthal, John Danesh, George Davey Smith, David DeMets, Stephen Evans, Malcolm Law, Stephen MacMahon, Seth Martin, Bruce Neal, Neil Poulter, David Preiss, Paul Ridker, Ian Roberts, Anthony Rodgers, Peter Sandercock, Kenneth Schulz, Peter Sever, John Simes, Liam Smeeth, Nicholas Wald, Salim Yusuf, Richard Peto
Nov 22, 2017
This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention of heart attacks and strokes. It explains how the evidence that is available from randomised...
An Exploration of the Relationships Between Different Reading Strategies and IELTS Test Performance
This study explores which types of IELTS Academic Reading strategies are used, and the impact of these strategies on test outcomes. The study was a quantitative research, using descriptive-correlational design based on data...
Published by: IGI Global Scientific Publishing
A Semi-Automated Data Pipeline for Predicting Lunar Impactor Diameters From Pre-Impact Topography and Ray Geometry
Liam Powers
Jan 01, 0001
The cause of asymmetries in ray systems created by impact craters has long remained a mystery. Sabuwala et al. (2018) showed that a relation exists between the creation of prominent rays, impactor diameter, and the number of...
lunar craters data automation elevation profiles ray geometry Physical Sciences and Mathematics Physics
Published by: Ursinus College
The Spatial Relationship Between Tycho Secondary Craters and Distal Impact Melt Deposits
Liam Powers
Jan 01, 0001
Study and analysis of Tycho's secondary crater populations in relation to previously identified impact melt and ray systems.
Published by: Ursinus College
Automatic Data Aggregation to Assist in the Systematic Classification of Small Lunar Craters
Liam Powers
Jan 01, 0001
Crater counting has been one of the dominant methods of characterizing surfaces of planetary bodies in the absence of material samples. Unfortunately, counts often rely on the subjective expertise of the counter, which limits...
Crater counting elevation profiles lunar craters Data analysis accuracy MODEL Physical Sciences and Mathematics Physics
Published by: Ursinus College
Realising the full potential of data-enabled trials in the UK
Matthew R Sydes, Yolanda Barbachano, Louise Bowman, Tom Denwood, Andrew Farmer, Steph Garfield-Birkbeck, Martin Gibson, Martin C Gulliford, David A Harrison, Catherine Hewitt, Jennifer Logue, Will Navaie, John Norrie, Martin O'Kane, Jennifer K Quint, Jo Rycroft-Malone, Jonathan Sheffield, Liam Smeeth, Frank Sullivan, Juliet Tizzard, Paula Walker, John Wilding, Paula R Williamson, Martin Landray, Andrew Morris, Rhoswyn R Walker, Hywel C Williams, Janet Valentine, Data Enabled Trials Group Workshop Group members
May 07, 2021
'From Cradle to Grave?'
While death features widely in various humanities and some social science disciplines, to date it has not been given the attention it deserves in social policy discourse or research. This paper sets out to begin to rectify...
'From Cradle to Grave?'
While death features widely in various humanities and some social science disciplines, to date it has not been given the attention it deserves in social policy discourse or research. This paper sets out to begin to rectify...
Anomaly Detection in Batch Manufacturing Processes Using Localized Reconstruction Errors From 1-D Convolutional AutoEncoders
Multivariate batch time-series data sets within Semiconductor manufacturing processes present a difficult environment for effective Anomaly Detection (AD). The challenge is amplified by the limited availability of ground truth...
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