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Cover Image for Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014 View Article
Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014
William Tillett, Lihi Eder, Niti Goel, Maarten de Wit, Dafna D Gladman, Oliver FitzGerald, Willemina Campbell, Philip S Helliwell, Laure Gossec, Ana-Maria Orbai, Alexis Ogdie, Vibeke Strand, Neil J McHugh, Philip J Mease
May 01, 2015

OBJECTIVE: To discuss the need for revision of the "core set" of domains to be included for assessment in psoriatic arthritis (PsA) randomized controlled trials and longitudinal observational studies, review work undertaken...

Cover Image for Patient involvement in outcome measures for psoriatic arthritis View Article
Patient involvement in outcome measures for psoriatic arthritis
William Tillett, Ade Adebajo, Mel Brooke, Willemina Campbell, Laura C Coates, Oliver FitzGerald, Laure Gossec, Philip Helliwell, Sarah Hewlett, Jana James, Patricia Minnock, Aisling Reast, Dennis O'Sullivan, Maarten de Wit, Neil McHugh
May 01, 2014
Psoriatic arthritis (PsA) is a heterogeneous inflammatory arthritis with a varied clinical phenotype. There has been considerable international collaboration over recent years to develop and prioritise appropriate disease...
Cover Image for Effect of filgotinib on health-related quality of life in active psoriatic arthritis View Article
Effect of filgotinib on health-related quality of life in active psoriatic arthritis
Ana-Maria Orbai, Alexis Ogdie, Laure Gossec, William Tillett, Ying Ying Leung, Jingjing Gao, Mona Trivedi, Chantal Tasset, Luc Meuleners, Robin Besuyen, Thijs Hendrikx, Laura C Coates
Jul 01, 2020

To examine the effects of filgotinib, an oral, selective Janus kinase 1 inhibitor, on health-related quality of life (HRQoL) using the Psoriatic Arthritis Impact of Disease (PsAID)9 questionnaire in active PsA. Methods...

DMARDs clinical trials and methods outcome measures psoriatic arthritis Quality of life
Cover Image for Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014 View Article
Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014
William Tillett, Lihi Eder, Niti Goel, Maarten de Wit, Dafna D Gladman, Oliver FitzGerald, Willemina Campbell, Philip S Helliwell, Laure Gossec, Ana-Maria Orbai, Alexis Ogdie, Vibeke Strand, Neil J McHugh, Philip J Mease
May 01, 2015

OBJECTIVE: To discuss the need for revision of the "core set" of domains to be included for assessment in psoriatic arthritis (PsA) randomized controlled trials and longitudinal observational studies, review work undertaken...

Cover Image for Effect of filgotinib on health-related quality of life in active psoriatic arthritis View Article
Effect of filgotinib on health-related quality of life in active psoriatic arthritis
Ana-Maria Orbai, Alexis Ogdie, Laure Gossec, William Tillett, Ying Ying Leung, Jingjing Gao, Mona Trivedi, Chantal Tasset, Luc Meuleners, Robin Besuyen, Thijs Hendrikx, Laura C Coates
Jul 01, 2020

To examine the effects of filgotinib, an oral, selective Janus kinase 1 inhibitor, on health-related quality of life (HRQoL) using the Psoriatic Arthritis Impact of Disease (PsAID)9 questionnaire in active PsA. Methods...

DMARDs clinical trials and methods outcome measures psoriatic arthritis Quality of life
Cover Image for Patient involvement in outcome measures for psoriatic arthritis View Article
Patient involvement in outcome measures for psoriatic arthritis
William Tillett, Ade Adebajo, Mel Brooke, Willemina Campbell, Laura C Coates, Oliver FitzGerald, Laure Gossec, Philip Helliwell, Sarah Hewlett, Jana James, Patricia Minnock, Aisling Reast, Dennis O'Sullivan, Maarten de Wit, Neil McHugh
May 01, 2014
Psoriatic arthritis (PsA) is a heterogeneous inflammatory arthritis with a varied clinical phenotype. There has been considerable international collaboration over recent years to develop and prioritise appropriate disease...
Cover Image for Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting View Article
Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting
Ana-Maria Orbai, Philip J Mease, Maarten de Wit, Umut Kalyoncu, Willemina Campbell, William Tillett, Lihi Eder, Musaab Elmamoun, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Chris A Lindsay, Ingrid Steinkoenig, Philip S Helliwell, Neil J McHugh, Vibeke Strand, Alexis Ogdie
May 01, 2016

The GRAPPA-OMERACT psoriatic arthritis (PsA) working group is in the process of updating the PsA core domain set to improve and standardize the measurement of PsA outcomes. Work streams comprise literature reviews of domains...

Cover Image for Initiating Evaluation of Composite Outcome Measures for Psoriatic Arthritis View Article
Initiating Evaluation of Composite Outcome Measures for Psoriatic Arthritis
Ying-Ying Leung, William Tillett, Maarten de Wit, Ana-Maria Orbai, Laura C Coates, Oliver FitzGerald, Philip S Helliwell, Vibeke Strand, Philip J Mease, Niti Goel, Robin Christensen, Joseph F Merola, Christine A Lindsay, Alexis Ogdie, Laure Gossec, Dafna D Gladman
Nov 01, 2023

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group-comprising rheumatologists, dermatologists...

GRAPPA composite outcome measures outcome measures Physical function psoriasis psoriatic arthritis
Cover Image for PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials View Article
PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials
Ana-Maria Orbai, Richard Holland, Ying Ying Leung, William Tillett, Niti Goel, Robin Christensen, Neil McHugh, Laure Gossec, Maarten de Wit, Pil Højgaard, Laura C Coates, Philip J Mease, Julie Birt, Lara Fallon, Oliver FitzGerald, Alexis Ogdie, Beverly Shea, Vibeke Strand, Kristina Callis Duffin, Peter Tugwell, Dorcas Beaton, Dafna D Gladman
Aug 01, 2019

OBJECTIVE: The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group is developing a Core Outcome Measurement...

Cover Image for PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials View Article
PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials
Ana-Maria Orbai, Richard Holland, Ying Ying Leung, William Tillett, Niti Goel, Robin Christensen, Neil McHugh, Laure Gossec, Maarten de Wit, Pil Højgaard, Laura C Coates, Philip J Mease, Julie Birt, Lara Fallon, Oliver FitzGerald, Alexis Ogdie, Beverly Shea, Vibeke Strand, Kristina Callis Duffin, Peter Tugwell, Dorcas Beaton, Dafna D Gladman
Aug 01, 2019

OBJECTIVE: The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group is developing a Core Outcome Measurement...

Cover Image for Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting View Article
Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting
Ana-Maria Orbai, Philip J Mease, Maarten de Wit, Umut Kalyoncu, Willemina Campbell, William Tillett, Lihi Eder, Musaab Elmamoun, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Chris A Lindsay, Ingrid Steinkoenig, Philip S Helliwell, Neil J McHugh, Vibeke Strand, Alexis Ogdie
May 01, 2016

The GRAPPA-OMERACT psoriatic arthritis (PsA) working group is in the process of updating the PsA core domain set to improve and standardize the measurement of PsA outcomes. Work streams comprise literature reviews of domains...

Cover Image for Updating the Psoriatic Arthritis (PsA) core domain set View Article
Updating the Psoriatic Arthritis (PsA) core domain set
Ana-Maria Orbai, Maarten de Wit, Philip J Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M van der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi Eder, Neil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, Alexis Ogdie
Oct 01, 2017

OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and...

Cover Image for Initiating Evaluation of Composite Outcome Measures for Psoriatic Arthritis View Article
Initiating Evaluation of Composite Outcome Measures for Psoriatic Arthritis
Ying-Ying Leung, William Tillett, Maarten de Wit, Ana-Maria Orbai, Laura C Coates, Oliver FitzGerald, Philip S Helliwell, Vibeke Strand, Philip J Mease, Niti Goel, Robin Christensen, Joseph F Merola, Christine A Lindsay, Alexis Ogdie, Laure Gossec, Dafna D Gladman
Nov 01, 2023

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group-comprising rheumatologists, dermatologists...

GRAPPA composite outcome measures outcome measures Physical function psoriasis psoriatic arthritis
Cover Image for A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis View Article
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018

BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.

OBJECTIVES: To synthesize...

Arthritis Humans Patient Reported Outcome Measures Quality of life Severity of Illness Index
Cover Image for A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis View Article
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018

BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.

OBJECTIVES: To synthesize...

Arthritis Humans Patient Reported Outcome Measures Quality of life Severity of Illness Index
Cover Image for Updating the Psoriatic Arthritis (PsA) core domain set View Article
Updating the Psoriatic Arthritis (PsA) core domain set
Ana-Maria Orbai, Maarten de Wit, Philip J Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M van der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi Eder, Neil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, Alexis Ogdie
Oct 01, 2017

OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and...

Cover Image for Zinc isotope evidence for sulfate-rich fluid transfer across subduction zones View Article
Zinc isotope evidence for sulfate-rich fluid transfer across subduction zones
Marie-Laure Pons, Baptiste Debret, Pierre Bouilhol, Adélie Delacour, Helen M Williams
Dec 05, 2016
Cover Image for The Reflexive Mind in Doris Lessing’s Landlocked > Poem and Novel View Article
The Reflexive Mind in Doris Lessing’s Landlocked > Poem and Novel
Dr Anne-Laure Brevet
Apr 23, 2021
Doris Lessing’s poem “Landlocked” was published on December, 20th 1946 in the daily newspaper New Rhodesia and remains little known as it was not included in the 1959 Fourteen Poems collection. Plausibly, one of the reasons for...
Cover Image for Error rate on the director's task is influenced by the need to take another's perspective but not the type of perspective. View Article
Error rate on the director's task is influenced by the need to take another's perspective but not the type of perspective.
Edward W Legg, Laure Olivier, Steven Samuel, Robert Lurz, Nicola S Clayton
Jan 17, 2018
Adults are prone to responding erroneously to another's instructions based on what they themselves see and not what the other person sees. Previous studies have indicated that in instruction-following tasks participants make...
Level 2 perspective-taking director's task perspective-taking Theory of mind
Cover Image for Low-noise, high-brightness, tunable source of picosecond pulsed light in the near-infrared and visible View Article
Low-noise, high-brightness, tunable source of picosecond pulsed light in the near-infrared and visible
Peter James Mosley, Samuel A Bateman, Laure Lavoute, William J Wadsworth
Nov 28, 2011
We have built a flexible source of picosecond pulsed light in both the near-infrared and visible spectral regions. A photonic crystal fiber (PCF) was pumped with a pulsed 1064 nm fiber laser to generate four-wave mixing (FWM)...
Cover Image for Low-noise, high-brightness, tunable source of picosecond pulsed light in the near-infrared and visible View Article
Low-noise, high-brightness, tunable source of picosecond pulsed light in the near-infrared and visible
Peter James Mosley, Samuel A Bateman, Laure Lavoute, William J Wadsworth
Nov 28, 2011
We have built a flexible source of picosecond pulsed light in both the near-infrared and visible spectral regions. A photonic crystal fiber (PCF) was pumped with a pulsed 1064 nm fiber laser to generate four-wave mixing (FWM)...
Cover Image for Neoadjuvant trials in early breast cancer View Article
Neoadjuvant trials in early breast cancer
Helena Earl, Elena Provenzano, Jean Abraham, Janet Dunn, Anne-Laure Vallier, Ioannis Gounaris, Louise Hiller
Sep 29, 2016
BACKGROUND: Neoadjuvant breast cancer trials are important for speeding up the introduction of new treatments for patients with early breast cancer and for the highly productive translational research which they facilitate....
Breast Neoplasms Female Humans Neoadjuvant Therapy Prognosis Treatment Outcome
Cover Image for Nutrient sensing and acquisition in fungi View Article
Nutrient sensing and acquisition in fungi
Louise E. Johns, Gustavo H. Goldman, Laure N.A. Ries, Neil A. Brown
Jun 30, 2021

Fungal pathogens destroy our crops and cause hazardous human infections, therefore threatening our health and food security. The ability of fungal pathogens to sense and respond to dynamic host microenvironments enables the...

Adaptation Fungal pathogen nutrient Sensing Uptake
Cover Image for A Novel Human Pluripotent Stem Cell-Derived Neural Crest Model of Treacher Collins Syndrome Shows Defects in Cell Death and Migration. View Article
A Novel Human Pluripotent Stem Cell-Derived Neural Crest Model of Treacher Collins Syndrome Shows Defects in Cell Death and Migration.
Felipe Serrano, William George Bernard, Alessandra Granata, Dharini Iyer, Ben Steventon, Matthew Kim, Ludovic Vallier, Laure Gambardella, Sanjay Sinha
Dec 10, 2018
The neural crest (NC) is a transient multipotent cell population present during embryonic development. The NC can give rise to multiple cell types and is involved in a number of different diseases. Therefore, the development of...
Treacher Collins syndrome DIFFERENTIATION Disease Modeling Human pluripotent stem cells Neural Crest Adaptor Proteins Signal Transducing Animals Benzamides Cell Death Cell Differentiation Cell Movement Cellular Reprogramming Techniques Chick Embryo Dioxoles Fibroblast Growth Factor 2 Humans Mandibulofacial Dysostosis Neural Crest Neural Stem Cells Nuclear Proteins Phosphoproteins Pluripotent Stem Cells SOXE Transcription Factors Transcription Factor AP-2 Transcription Factors Twist-Related Protein 1
Cover Image for Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells. View Article
Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells.
Emmanuel Than-Trong, Bahareh Kiani, Nicolas Dray, Sara Ortica, Benjamin Simons, Steffen Rulands, Alessandro Alunni, Laure Bally-Cuif
Jan 20, 2021
The cellular basis and extent of neural stem cell (NSC) self-renewal in adult vertebrates, and their heterogeneity, remain controversial. To explore the functional behavior and dynamics of individual NSCs, we combined genetic...
Adult stem cells Animals Cell Differentiation Neural Stem Cells Neurogenesis Telencephalon Zebrafish

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