Search
Results: 26
The Isolation and Characterization of Soluble Brain Proteins
Gudrun Staub Bennett
Jan 01, 0001
The experiments described in this thesis were undertaken in order to define and purify proteins that might have a specific function in nerve activity. The studies were limited to rat brain proteins soluble in dilute aqueous...
Published by: Rockefeller University
Simplifying the OpenFlexure microscope software with the web of things.
Joel T Collins, Joe Knapper, Samuel McDermott, Filip Ayazi, Kaspar E Bumke, Julian Stirling, Richard W Bowman
Nov 22, 2021
We present the OpenFlexure Microscope software stack which provides computer control of our open source motorised microscope. Our diverse community of users needs both graphical and script-based interfaces. We split the control...
Characterisation of canine KCNIP4
Christopher A. Jenkins, Lajos Kalmar, Kaspar Matiasek, Lorenzo Mari, Kaisa Kyöstilä, Hannes Lohi, Ellen C. Schofield, Cathryn S. Mellersh, Luisa De Risio, Sally L. Ricketts
Feb 11, 2020
A form of hereditary cerebellar ataxia has recently been described in the Norwegian Buhund dog breed. This study aimed to identify the genetic cause of the disease. Whole-genome sequencing of two Norwegian Buhund siblings...
Conditional power and friends
Kevin Kunzmann, Michael J Grayling, Kim May Lee, David S Robertson, Kaspar Rufibach, James MS Wason
Jan 28, 2022
Adapting the final sample size of a trial to the evidence accruing during the trial is a natural way to address planning uncertainty. Since the sample size is usually determined by an argument based on the power of the trial, an...
Characterisation of canine KCNIP4
Christopher A Jenkins, Lajos Kalmar, Kaspar Matiasek, Lorenzo Mari, Kaisa Kyöstilä, Hannes Lohi, Ellen C Schofield, Cathryn S Mellersh, Luisa De Risio, Sally L Ricketts
Mar 02, 2020
A form of hereditary cerebellar ataxia has recently been described in the Norwegian Buhund dog breed. This study aimed to identify the genetic cause of the disease. Whole-genome sequencing of two Norwegian Buhund siblings...
dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts.
Vadim Demichev, Lukasz Szyrwiel, Fengchao Yu, Guo Ci Teo, George Rosenberger, Agathe Niewienda, Daniela Ludwig, Jens Decker, Stephanie Kaspar-Schoenefeld, Kathryn Lilley, Michael Mülleder, Alexey I Nesvizhskii, Markus Ralser
Jul 08, 2022
The dia-PASEF technology uses ion mobility separation to reduce signal interferences and increase sensitivity in proteomic experiments. Here we present a two-dimensional peak-picking algorithm and generation of optimized...
Simplifying the OpenFlexure microscope software with the web of things.
Joel T Collins, Joe Knapper, Samuel J McDermott, Filip Ayazi, Kaspar E Bumke, Julian Stirling, Richard W Bowman
Jan 07, 2022
We present the OpenFlexure Microscope software stack which provides computer control of our open source motorised microscope. Our diverse community of users needs both graphical and script-based interfaces. We split the control...
dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts.
Vadim Demichev, Lukasz Szyrwiel, Fengchao Yu, Guo Ci Teo, George Rosenberger, Agathe Niewienda, Daniela Ludwig, Jens Decker, Stephanie Kaspar-Schoenefeld, Kathryn S Lilley, Michael Mülleder, Alexey I Nesvizhskii, Markus Ralser
Aug 08, 2022
The dia-PASEF technology uses ion mobility separation to reduce signal interferences and increase sensitivity in proteomic experiments. Here we present a two-dimensional peak-picking algorithm and generation of optimized...
Mutations in glycyl-tRNA synthetase impair mitochondrial metabolism in neurons.
Veronika Boczonadi, Kathrin Meyer, Humberto Gonczarowska-Jorge, Helen Griffin, Andreas Roos, Marina Bartsakoulia, Boglarka Bansagi, Giulia Ricci, Fanni Palinkas, René P Zahedi, Francesco Bruni, Brian Kaspar, Hanns Lochmüller, Kym M Boycott, Juliane S Müller, Rita Horvath
Mar 21, 2019
The nuclear-encoded glycyl-tRNA synthetase gene (GARS) is essential for protein translation in both cytoplasm and mitochondria. In contrast, different genes encode the mitochondrial and cytosolic forms of most other tRNA...
Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America.
Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors.
Maria Didriksen, Richard P Allen, Brendan J Burchell, Lise W Thørner, Andreas S Rigas, Emanuele Di Angelantonio, Maria H Nielsen, Poul J Jennum, Thomas Werge, Christian Erikstrup, Ole B Pedersen, Kaspar Nielsen, Mie T Bruun, Kristoffer S Burgdorf, Erik Sørensen, Henrik Ullum
Aug 20, 2018
BACKGROUND: Restless Legs Syndrome (RLS) is characterized by uncomfortable nocturnal sensations in the legs making sedentary activities and sleep difficult, and is thus linked with psychosocial distress. Due to the...
Comorbidities Depressive Disorder Quality of life Restless Legs Syndrome Sleep disturbance The Danish blood donor study Adult Blood Donors Comorbidity Denmark Depressive Disorder Female Health Surveys Humans Male prevalence Quality of life Restless Legs Syndrome Sex Factors Sleep Wake Disorders Stress Psychological Surveys and Questionnaires
Higgs-mass predictions in the MSSM and beyond
P Slavich, S Heinemeyer, E Bagnaschi, H Bahl, M Goodsell, HE Haber, T Hahn, R Harlander, W Hollik, G Lee, M Mühlleitner, S Paßehr, H Rzehak, D Stöckinger, A Voigt, CEM Wagner, G Weiglein, BC Allanach, T Biekötter, S Borowka, J Braathen, M Carena, TN Dao, G Degrassi, F Domingo, P Drechsel, U Ellwanger, M Gabelmann, R Gröber, J Klappert, T Kwasnitza, D Meuser, L Mihaila, N Murphy, K Nickel, W Porod, EAR Rojas, I Sobolev, F Staub
Jul 07, 2021
Predictions for the Higgs masses are a distinctive feature of supersymmetric
extensions of the Standard Model, where they play a crucial role in
constraining the parameter space. The discovery of a Higgs boson and the
remarkably...
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits.
Guillaume M Hautbergue, Lydia M Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S Bauer, Jennifer E Dodd, Monika A Myszczynska, Sarah M Alam, Pierre Garneret, Jayanth S Chandran, Evangelia Karyka, Matthew J Stopford, Emma F Smith, Janine Kirby, Kathrin Meyer, Brian K Kaspar, Adrian M Isaacs, Sherif F El-Khamisy, Kurt J De Vos, Ke Ning, Mimoun Azzouz, Alexander J Whitworth, Pamela J Shaw
Dec 17, 2018
Adult Aged Amyotrophic Lateral Sclerosis Animals Astrocytes C9orf72 Protein Cell Line Coculture Techniques Disease Models Animal Drosophila Female frontotemporal dementia Humans Male Mice Middle Aged Nuclear Proteins Nucleocytoplasmic Transport Proteins RNA-Binding Proteins Rats Serine-Arginine Splicing Factors Transcription Factors
Higgs-mass predictions in the MSSM and beyond
P. Slavich, S. Heinemeyer, E. Bagnaschi, H. Bahl, M. Goodsell, H. E. Haber, T. Hahn, R. Harlander, W. Hollik, G. Lee, M. Mühlleitner, S. Paßehr, H. Rzehak, D. Stöckinger, A. Voigt, C. E. M. Wagner, G. Weiglein, B. C. Allanach, T. Biekötter, S. Borowka, J. Braathen, M. Carena, T. N. Dao, G. Degrassi, F. Domingo, P. Drechsel, U. Ellwanger, M. Gabelmann, R. Gröber, J. Klappert, T. Kwasnitza, D. Meuser, L. Mihaila, N. Murphy, K. Nickel, W. Porod, E. A. Reyes Rojas, I. Sobolev, F. Staub
May 26, 2021
Abstract: Predictions for the Higgs masses are a distinctive feature of supersymmetric extensions of the Standard Model, where they play a crucial role in constraining the parameter space. The discovery of a Higgs boson and the...
Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Kylie E Hunter, Brittany J Johnson, Lisa Askie, Rebecca K Golley, Louise A Baur, Ian C Marschner, Rachael W Taylor, Luke Wolfenden, Charles T Wood, Seema Mihrshahi, Alison J Hayes, Chris Rissel, Kristy P Robledo, Denise A O'Connor, David Espinoza, Lukas P Staub, Paul Chadwick, Sarah Taki, Angie Barba, Sol Libesman, Mason Aberoumand, Wendy A Smith, Michelle Sue-See, Kylie D Hesketh, Jessica L Thomson, Maria Bryant, Ian M Paul, Vera Verbestel, Cathleen Odar Stough, Li Ming Wen, Junilla K Larsen, Sharleen L O'Reilly, Heather M Wasser, Jennifer S Savage, Ken K Ong, Sarah-Jeanne Salvy, Mary Jo Messito, Rachel S Gross, Levie T Karssen, Finn E Rasmussen, Karen Campbell, Ana Maria Linares, Nina Cecilie Øverby, Cristina Palacios, Kaumudi J Joshipura, Carolina González Acero, Rajalakshmi Lakshman, Amanda L Thompson, Claudio Maffeis, Emily Oken, Ata Ghaderi, Maribel Campos Rivera, Ana B Pérez-Expósito, Jinan C Banna, Kayla de la Haye, Michael Goran, Margrethe Røed, Stephanie Anzman-Frasca, Barry J Taylor, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Feb 21, 2022
INTRODUCTION: Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs...
Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration
Brittany J Johnson, Kylie E Hunter, Rebecca K Golley, Paul Chadwick, Angie Barba, Mason Aberoumand, Sol Libesman, Lisa Askie, Rachael W Taylor, Kristy P Robledo, Seema Mihrshahi, Denise A O'Connor, Alison J Hayes, Luke Wolfenden, Charles T Wood, Louise A Baur, Chris Rissel, Lukas P Staub, Sarah Taki, Wendy Smith, Michelle Sue-See, Ian C Marschner, David Espinoza, Jessica L Thomson, Junilla K Larsen, Vera Verbestel, Cathleen Odar Stough, Sarah-Jeanne Salvy, Sharleen L O'Reilly, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Maria Bryant, Ian M Paul, Li Ming Wen, Kylie D Hesketh, Carolina González Acero, Karen Campbell, Nina Cecilie Øverby, Ana M Linares, Heather M Wasser, Kaumudi J Joshipura, Cristina Palacios, Claudio Maffeis, Amanda L Thompson, Ata Ghaderi, Rajalakshmi Lakshman, Jinan C Banna, Emily Oken, Maribel Campos Rivera, Ana B Pérez-Expósito, Barry J Taylor, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Feb 21, 2022
INTRODUCTION: Little is known about how early (eg, commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study...
Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration
Brittany J Johnson, Kylie E Hunter, Rebecca K Golley, Paul Chadwick, Angie Barba, Mason Aberoumand, Sol Libesman, Lisa Askie, Rachael W Taylor, Kristy P Robledo, Seema Mihrshahi, Denise A O'Connor, Alison J Hayes, Luke Wolfenden, Charles T Wood, Louise A Baur, Chris Rissel, Lukas P Staub, Sarah Taki, Wendy Smith, Michelle Sue-See, Ian C Marschner, David Espinoza, Jessica L Thomson, Junilla K Larsen, Vera Verbestel, Cathleen Odar Stough, Sarah-Jeanne Salvy, Sharleen L O'Reilly, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Maria Bryant, Ian M Paul, Li Ming Wen, Kylie D Hesketh, Carolina González Acero, Karen Campbell, Nina Cecilie Øverby, Ana M Linares, Heather M Wasser, Kaumudi J Joshipura, Cristina Palacios, Claudio Maffeis, Amanda L Thompson, Ata Ghaderi, Rajalakshmi Lakshman, Jinan C Banna, Emily Oken, Maribel Campos Rivera, Ana B Pérez-Expósito, Barry J Taylor, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Jan 28, 2022
INTRODUCTION: Little is known about how early (eg, commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study...
Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Kylie E Hunter, Brittany J Johnson, Lisa Askie, Rebecca K Golley, Louise A Baur, Ian C Marschner, Rachael W Taylor, Luke Wolfenden, Charles T Wood, Seema Mihrshahi, Alison J Hayes, Chris Rissel, Kristy P Robledo, Denise A O'Connor, David Espinoza, Lukas P Staub, Paul Chadwick, Sarah Taki, Angie Barba, Sol Libesman, Mason Aberoumand, Wendy A Smith, Michelle Sue-See, Kylie D Hesketh, Jessica L Thomson, Maria Bryant, Ian M Paul, Vera Verbestel, Cathleen Odar Stough, Li Ming Wen, Junilla K Larsen, Sharleen L O'Reilly, Heather M Wasser, Jennifer S Savage, Kenneth Ong, Sarah-Jeanne Salvy, Mary Jo Messito, Rachel S Gross, Levie T Karssen, Finn E Rasmussen, Karen Campbell, Ana Maria Linares, Nina Cecilie Øverby, Cristina Palacios, Kaumudi J Joshipura, Carolina González Acero, Rajalakshmi Lakshman, Amanda L Thompson, Claudio Maffeis, Emily Oken, Ata Ghaderi, Maribel Campos Rivera, Ana B Pérez-Expósito, Jinan C Banna, Kayla de la Haye, Michael Goran, Margrethe Røed, Stephanie Anzman-Frasca, Barry J Taylor, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Jan 28, 2022
INTRODUCTION: Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs...
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Steven Bell, Andreas S. Rigas, Magnus K. Magnusson, Egil Ferkingstad, Elias Allara, Gyda Bjornsdottir, Anna Ramond, Erik Sørensen, Gisli H. Halldorsson, Dirk S. Paul, Kristoffer S. Burgdorf, Hannes P. Eggertsson, Joanna M. M. Howson, Lise W. Thørner, Snaedis Kristmundsdottir, William J. Astle, Christian Erikstrup, Jon K. Sigurdsson, Dragana Vuckovic, Khoa M. Dinh, Vinicius Tragante, Praveen Surendran, Ole B. Pedersen, Brynjar Vidarsson, Tao Jiang, Helene M. Paarup, Pall T. Onundarson, Parsa Akbari, Kaspar R. Nielsen, Sigrun H. Lund, Kristinn Juliusson, Magnus I. Magnusson, Michael L. Frigge, Asmundur Oddsson, Isleifur Olafsson, Stephen Kaptoge, Henrik Hjalgrim, Gudmundur Runarsson, Angela M. Wood, Ingileif Jonsdottir, Thomas F. Hansen, Olof Sigurdardottir, Hreinn Stefansson, David Rye, James E. Peters, David Westergaard, Hilma Holm, Nicole Soranzo, Karina Banasik, Gudmar Thorleifsson, Willem H. Ouwehand, Unnur Thorsteinsdottir, David J. Roberts, Patrick Sulem, Adam S. Butterworth, Daniel F. Gudbjartsson, John Danesh, Søren Brunak, Emanuele Di Angelantonio, Henrik Ullum, Kari Stefansson, Steffen Andersen, Kristoffer Burgdorf, Gregor Jemec, Poul Jennum, Pär Johansson, Kasper R. Nielsen, Mette Nyegaard, Mikkel Petersen, Thomas Werge, Hreinn Stefánsson, Unnur Thorsteinsdóttir
Feb 03, 2021
Abstract: Iron is essential for many biological functions and iron deficiency and overload have major health implications. We performed a meta-analysis of three genome-wide association studies from Iceland, the UK and Denmark of...
Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.
Matthias W Lorenz, Lu Gao, Kathrin Ziegelbauer, Giuseppe Danilo Norata, Jean Philippe Empana, Irene Schmidtmann, Hung-Ju Lin, Stela McLachlan, Lena Bokemark, Kimmo Ronkainen, Mauro Amato, Ulf Schminke, Sathanur R Srinivasan, Lars Lind, Shuhei Okazaki, Coen DA Stehouwer, Peter Willeit, Joseph F Polak, Helmuth Steinmetz, Dirk Sander, Holger Poppert, Moise Desvarieux, M Arfan Ikram, Stein Harald Johnsen, Daniel Staub, Cesare R Sirtori, Bernhard Iglseder, Oscar Beloqui, Gunnar Engström, Alfonso Friera, Francesco Rozza, Wuxiang Xie, Grace Parraga, Liliana Grigore, Matthieu Plichart, Stefan Blankenberg, Ta-Chen Su, Caroline Schmidt, Tomi-Pekka Tuomainen, Fabrizio Veglia, Henry Völzke, Giel Nijpels, Johann Willeit, Ralph L Sacco, Oscar H Franco, Heiko Uthoff, Bo Hedblad, Carmen Suarez, Raffaele Izzo, Dong Zhao, Thapat Wannarong, Alberico Catapano, Pierre Ducimetiere, Christine Espinola-Klein, Kuo-Liong Chien, Jackie F Price, Göran Bergström, Jussi Kauhanen, Elena Tremoli, Marcus Dörr, Gerald Berenson, Kazuo Kitagawa, Jacqueline M Dekker, Stefan Kiechl, Matthias Sitzer, Horst Bickel, Tatjana Rundek, Albert Hofman, Ellisiv B Mathiesen, Samuela Castelnuovo, Manuel F Landecho, Maria Rosvall, Rafael Gabriel, Nicola de Luca, Jing Liu, Damiano Baldassarre, Maryam Kavousi, Eric de Groot, Michiel L Bots, David N Yanez, Simon G Thompson, PROG-IMT Study Group
Jun 19, 2018
AIMS: Carotid intima media thickness (CIMT) predicts cardiovascular (CVD) events, but the predictive value of CIMT change is debated. We assessed the relation between CIMT change and events in individuals at high cardiovascular...
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease
Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Mohammad Karaminejadranjbar, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson, Marlen Zurek, Caterina Strisciuglio, Mamoun Elawad, Bernice Lo, Carolina Arancibia-Carcamo, Adam Bailey, Ellie Barnes, Elizabeth Louise Bird-Lieberman, Oliver Brain, Barbara Braden, Jane Collier, James East, Lucy Howarth, Satish Keshav, Paul Klenerman, Simon Leedham, Rebecca Palmer, Fiona Powrie, Alison Simmons, Matthew Walker, Zoe Tolkien, Stephen Kaptoge, David Allen, Susan Mehenny, Jonathan Mant, Emanuele Di Angelantonio, Simon G. Thompson, Bahtiyar Yilmaz, Pascal Juillerat, Markus Geuking, Reiner Wiest, Andrew J. Macpherson, Francisco Damian Bravo, Lukas Brügger, Ove Carstens, Ulrike Graf Bigler, Benjamin Heimgartner, Monica Rusticeanu, Sybille Schmid (-Uebelhart), Bruno Strebel, Aurora Tatu, Radu Tutuian, Ove Øyås, Charlotte Ramon, Jörg Stelling, Yannick Franc, Nicolas Fournier, Valerie E. H. Pittet, Bernard Burnand, Mara Egger, Delphine Golay, Astrid Marot, Leilla Musso, Valérie Pittet, Jean-Benoît Rossel, Vivianne Seematter, Joachim Sommer, Rachel Vulliamy, Pierre Michetti, Michel H. Maillard, Céline Keller, Andreas Nydegger, Alain Schoepfe, Eva Archanioti, Jessica Ezri, Montserrat Fraga, Alain Schoepfer, Christoph Müller, Gerhard Rogler, Luc Biedermann, Mirjam Blattmann, Sabine Burk, Barbara Dora, Michael Fried, Benjamin Misselwitz, Beat Müllhaupt, Nicole Obialo, Daniel Pohl, Nadia Raschle, Michael Scharl, Stephan Vavricka, Roland Von Känel, Jonas Zeitz, Karim Abdelrahman, Gentiana Ademi, Jan Borovicka, Stephan Brand, Remus Frei, Johannes Haarer, Christina Knellwolf (-Grieger), Claudia Krieger(-Grübel), Patrizia Künzler, Christa Meyenberger, Pamela Meyer, Nina Röhrich, Mikael Sawatzki, Martin Schelling, Gian-Marco Semadeni, Michael Sulz, Dorothee Zimmermann, Patrick Aepli, Dominique H. Criblez, Cyrill Hess, Jean-Pierre Richterich, Johannes Spalinger, Dominic Staudenmann, Andreas Stulz, Stefanie Wöhrle, Amman Thomas, Claudia Anderegg, Henrik Köhler, Rachel Kusche, Anca-Teodora Antonino, Eviano Arrigoni, José M. Bengoa, Sophie Cunningham, Philippe de Saussure, Laurent Girard, Diana Bakker de Jong, Polat Bastürk, Simon Brunner, Lukas Degen, Petr Hruz, Carolina Khalid-de Bakker, Jan Niess, Bruno Balsiger, Janine Haldemann, Gaby Saner, Frank Seibold, Peter Bauerfeind, Andrea Becocci, Dominique Belli, Janek Binek, Peter Hengstler, Stephan Boehm, Tujana Boldanov, Patrick Bühr, Rebekka Koller, Vanessa Rueger, Arne Senning, Emanuel Burri, Sophie Buyse, Dahlia-Thao Cao, Fabrizia D’Angelo, Joakim Delarive, Christopher Doerig, Roxane Hessler, Claudia Preissler, Ronald Rentsch, Branislav Risti, Marc Alain Ritz, Michael Steuerwald, Jürg Vögtlin, Markus Sagmeister, Bernhard Sauter, Susanne Schibli, Christiane Sokollik, Hugo Schlauri, Jean-François Schnegg, Mariam Seirafi, Holger Spangenberger, Philippe Stadler, Peter Staub, Volker Stenz, Michela Tempia-Caliera, Joël Thorens, Kaspar Truninger, Patrick Urfer, Francesco Viani, Dominique Vouillamoz, Silvan Zander, Tina Wyli, L. Jostins, N. A. Kennedy, T. Ahmad, C. A. Lamb, C. Edwards, A. Hart, C. Hawkey, J. C. Mansfield, C. Mowat, W. G. Newman, A. Simmons, M. Tremelling, J. C. Lee, N. J. Prescott, C. G. Mathew, C. W. Lees, D. P. B. McGovern, S. R. Targan, G. Botwin, E. Mengesha, P. Fleshner, C. Landers, D. Li, J. D. Rioux, A. Bitton, J. Côté-Daigneault, M. J. Daly, R. Xavier, K. Morris, G. Boucher, J. H. Cho, C. Abraham, M. Merad, B. Sands, I. Peter, K. Hao, Y. Itan, R. H. Duerr, L. Konnikova, M. B. Schwartz, S. Proksell, E. Johnston, V. Miladinova, W. Chen, S. R. Brant, L. Datta, M. S. Silverberg, L. P. Schumm, S. Birch, M. Giri, K. Gettler, Y. Sharma, C. Stevens, M. Lazarev, T. Haritunians
Feb 20, 2021
Abstract: Very-early-onset inflammatory bowel disease (VEO-IBD) is a heterogeneous phenotype associated with a spectrum of rare Mendelian disorders. Here, we perform whole-exome-sequencing and genome-wide genotyping in 145...
Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertainty.
Nate Breznau, Eike Mark Rinke, Alexander Wuttke, Hung HV Nguyen, Muna Adem, Jule Adriaans, Amalia Alvarez-Benjumea, Henrik K Andersen, Daniel Auer, Flavio Azevedo, Oke Bahnsen, Dave Balzer, Gerrit Bauer, Paul C Bauer, Markus Baumann, Sharon Baute, Verena Benoit, Julian Bernauer, Carl Berning, Anna Berthold, Felix S Bethke, Thomas Biegert, Katharina Blinzler, Johannes N Blumenberg, Licia Bobzien, Andrea Bohman, Thijs Bol, Amie Bostic, Zuzanna Brzozowska, Katharina Burgdorf, Kaspar Burger, Kathrin B Busch, Juan Carlos-Castillo, Nathan Chan, Pablo Christmann, Roxanne Connelly, Christian S Czymara, Elena Damian, Alejandro Ecker, Achim Edelmann, Maureen A Eger, Simon Ellerbrock, Anna Forke, Andrea Forster, Chris Gaasendam, Konstantin Gavras, Vernon Gayle, Theresa Gessler, Timo Gnambs, Amélie Godefroidt, Max Grömping, Martin Groß, Stefan Gruber, Tobias Gummer, Andreas Hadjar, Jan Paul Heisig, Sebastian Hellmeier, Stefanie Heyne, Magdalena Hirsch, Mikael Hjerm, Oshrat Hochman, Andreas Hövermann, Sophia Hunger, Christian Hunkler, Nora Huth, Zsófia S Ignácz, Laura Jacobs, Jannes Jacobsen, Bastian Jaeger, Sebastian Jungkunz, Nils Jungmann, Mathias Kauff, Manuel Kleinert, Julia Klinger, Jan-Philipp Kolb, Marta Kołczyńska, John Kuk, Katharina Kunißen, Dafina Kurti Sinatra, Alexander Langenkamp, Philipp M Lersch, Lea-Maria Löbel, Philipp Lutscher, Matthias Mader, Joan E Madia, Natalia Malancu, Luis Maldonado, Helge Marahrens, Nicole Martin, Paul Martinez, Jochen Mayerl, Oscar J Mayorga, Patricia McManus, Kyle McWagner, Cecil Meeusen, Daniel Meierrieks, Jonathan Mellon, Friedolin Merhout, Samuel Merk, Daniel Meyer, Leticia Micheli, Jonathan Mijs, Cristóbal Moya, Marcel Neunhoeffer, Daniel Nüst, Olav Nygård, Fabian Ochsenfeld, Gunnar Otte, Anna O Pechenkina, Christopher Prosser, Louis Raes, Kevin Ralston, Miguel R Ramos, Arne Roets, Jonathan Rogers, Guido Ropers, Robin Samuel, Gregor Sand, Ariela Schachter, Merlin Schaeffer, David Schieferdecker, Elmar Schlueter, Regine Schmidt, Katja M Schmidt, Alexander Schmidt-Catran, Claudia Schmiedeberg, Jürgen Schneider, Martijn Schoonvelde, Julia Schulte-Cloos, Sandy Schumann, Reinhard Schunck, Jürgen Schupp, Julian Seuring, Henning Silber, Willem Sleegers, Nico Sonntag, Alexander Staudt, Nadia Steiber, Nils Steiner, Sebastian Sternberg, Dieter Stiers, Dragana Stojmenovska, Nora Storz, Erich Striessnig, Anne-Kathrin Stroppe, Janna Teltemann, Andrey Tibajev, Brian Tung, Giacomo Vagni, Jasper Van Assche, Meta van der Linden, Jolanda van der Noll, Arno Van Hootegem, Stefan Vogtenhuber, Bogdan Voicu, Fieke Wagemans, Nadja Wehl, Hannah Werner, Brenton M Wiernik, Fabian Winter, Christof Wolf, Yuki Yamada, Nan Zhang, Conrad Ziller, Stefan Zins, Tomasz Żółtak
Nov 28, 2022
This study explores how researchers' analytical choices affect the reliability of scientific findings. Most discussions of reliability problems in science focus on systematic biases. We broaden the lens to emphasize the...
|
|< |
< |
1 |