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Scholarship Endowment Commemorates Late Alumna Lin Fearrington Thomas '81, '83
Winthrop University
Jan 01, 0001
Recent endowment has made the Lin Fearrington Thomas Scholarship a permanent fund at Winthrop. Thomas earned B.A. and M.B.A. degrees as a post-traditional student in the 1980s.
Published by: Winthrop University
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Jan 22, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation.
Sympathetic neurons depend on NGF binding to TrkA for their survival during vertebrate development. NGF deprivation initiates a transcription-dependent apoptotic response, which is suggested to require activation of the...
Animals Apoptosis Base Sequence Brain-Derived Neurotrophic Factor Cells Cultured Cycloheximide Gene Expression Regulation Developmental Genetic Vectors Green Fluorescent Proteins Immunohistochemistry Indicators and Reagents Integrases Luminescent Proteins Mice Mice Knockout Mutation Nerve Growth Factor Neurons Protein Synthesis Inhibitors Proto-Oncogene Proteins c-jun Receptor Nerve Growth Factor Superior Cervical Ganglion Transfection Viral Proteins
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Mar 15, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Learning Sparrow Algorithm With Non-Uniform Search for Global Optimization
Sparrow Algorithm as a New Swarm Intelligence Search Algorithm, the sparrow algorithm has good optimization ability, but in complex environments, it still has certain limitations, such as weak learning ability. Therefore, this...
Published by: IGI Global Scientific Publishing
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
Liquid jet leaping from a free surface
We investigate the characteristics of a liquid jet ejected from an inclined tube, which is submerged immediately under a free surface. Jets are classified into three regimes: the curtain regime, transition regime, and column...
Rotatable precipitates change the scale-free to scale dependent statistics in compressed Ti nano-pillars.
Yan Pan, Haijun Wu, Xiaofei Wang, Qiaoyan Sun, Lin Xiao, Xiangdong Ding, Jun Sun, Ekhard KH Salje
May 09, 2019
Compressed nano-pillars crackle from moving dislocations, which reduces plastic stability. Crackling noise is characterized by stress drops or strain bursts, which scale over a large region of sizes leading to power law...
Liquid jet leaping from a free surface
We investigate the characteristics of a liquid jet ejected from an inclined tube, which is submerged immediately under a free surface. Jets are classified into three regimes: the curtain regime, transition regime, and column...
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
DREAM represses distinct targets by cooperating with different THAP domain proteins.
Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Yan Dong, Jane Murphy, Andrea Frapporti, Julie Ahringer
Sep 27, 2021
The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two...
dream H2A.Z H3K9me2 THAP lin-15B lin-35 lin-36 quiescence retinoblastoma TRANSCRIPTIONAL REPRESSION Animals Animals Genetically Modified Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Proteins DNA Methylation E2F Transcription Factors Gene Expression Regulation Histones Promoter Regions Genetic Protein Binding Protein Interaction Domains and Motifs Retinoblastoma Protein Transcription Factors
Evaluation of a GNSS for wave measurement and directional wave spectrum analysis
Wave buoys are important devices to monitor and analyze wave data for ocean and coastal engineering. A GNSS wave buoy is briefly introduced in the paper, which has high resolution to measure the buoy motion by vertical...
A protein complex required for polar growth of rhizobial infection threads
Cheng-Wu Liu, Andrew Breakspear, Nicola Stacey, Kim Findlay, Jin Nakashima, Karunakaran Ramakrishnan, Miaoxia Liu, Fang Xie, Gabriella Endre, Fernanda de Carvalho-Niebel, Giles E. D. Oldroyd, Michael K. Udvardi, Joëlle Fournier, Jeremy D. Murray
Jun 27, 2020
Abstract: During root nodule symbiosis, intracellular accommodation of rhizobia by legumes is a prerequisite for nitrogen fixation. For many legumes, rhizobial colonization initiates in root hairs through transcellular infection...
Evaluation of a GNSS for wave measurement and directional wave spectrum analysis
Wave buoys are important devices to monitor and analyze wave data for ocean and coastal engineering. A GNSS wave buoy is briefly introduced in the paper, which has high resolution to measure the buoy motion by vertical...
Targeted fluorescence imaging enhanced by 2D materials
Donghao Xie, Ding Kun Ji, Yue Zhang, Jun Cao, Hu Zheng, Lin Liu, Yi Zang, Jia Li, Guo Rong Chen, Tony D. James, Xiao Peng He
Aug 04, 2016
Here we demonstrate that 2D MoS2 can enhance the receptor-targeting and imaging ability of a fluorophore-labelled ligand. The 2D MoS2 has an enhanced working concentration range when compared with...
Review of Terahertz Pulsed Imaging for Pharmaceutical Film Coating Analysis
Décio Alves-Lima, Jun Song, Xiaoran Li, Alessia Portieri, Yaochun Shen, J. Axel Zeitler, Hungyen Lin
Mar 10, 2020
Terahertz pulsed imaging (TPI) was introduced approximately fifteen years ago and has attracted a lot of interest in the pharmaceutical industry as a fast, non-destructive modality for quantifying film coatings on pharmaceutical...
Analysis of the Electrical and Thermal Properties for Magnetic Fe3O4-Coated SiC-Filled Epoxy Composites.
Jiale Wu, Yiran Zhang, Yangzhi Gong, Kun Wang, Yun Chen, Xupeng Song, Jun Lin, Boyang Shen, Shaojian He, Xingming Bian
Oct 29, 2021
Orderly arranged Silicon carbide (SiC)/epoxy (EP) composites were fabricated. SiC was made magnetically responsive by decorating the surface with iron oxide (Fe3O4) nanoparticles. Three treatment methods, including without...
Research on the Compound Optimization Method of the Electrical and Thermal Properties of SiC/EP Composite Insulating Material.
Xupeng Song, Xiaofeng Xue, Wen Qi, Jin Zhang, Yang Zhou, Wei Yang, Yiran Zhang, Boyang Shen, Jun Lin, Xingming Bian
Nov 22, 2021
In this paper, in order to improve the electrical and thermal properties of SiC/EP composites, the methods of compounding different crystalline SiC and micro-nano SiC particles are used to optimize them. Under different compound...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
Apr 02, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
May 15, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
Animals Basement Membrane Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Checkpoints Cell Differentiation Cell Proliferation G1 Phase Cell Cycle Checkpoints Gene Expression MDS1 and EVI1 Complex Locus Protein Proto-Oncogene Mas Proto-Oncogene Proteins c-fos Proto-Oncogenes Receptors Notch Signal Transduction Transcription Factors
Optimal design and performance analysis of a hybrid system combing a floating wind platform and wave energy converters
Jianjian Hu, Binzhen Zhou, Christopher Vogel, Pin Liu, Richard Willden, Ke Sun, Jun Zang, Jing geng, Peng Jin, Lin Cui, Maurizio Collu
Jul 01, 2020
Combined floating offshore wind platform and Wave Energy Converters (WECs) systems have the potential to provide a cost-effective solution to offshore power supply and platform protection. The objective of this paper is to...
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