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Isolated Systolic Hypertension in Young People Is Not Spurious and Should Be Treated
We agree with many of the points made by Lurbe and Redon,1 which were similar to those raised in our own article. Certainly, the ability to assess central blood pressure (BP) noninvasively has increased our understanding of...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel.
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For...
Reply.
We agree with many of the points made by Lurbe and Redon,1 which were similar to those raised in our own article. Certainly, the ability to assess central blood pressure (BP) noninvasively has increased our understanding of...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For each user...
Temporal trends in leisure-time sedentary behavior among adolescents aged 12-15 years from 26 countries in Asia, Africa, and the Americas.
BACKGROUND: Multi-country studies examining trends in sedentary behaviors among adolescents have mainly focused on high-income or Western countries, and almost no data exists for the rest of the world. Thus, this study aims to...
Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation.
The DNA-damage checkpoint kinase Chk1 is essential in higher eukaryotes due to its role in maintaining genome stability in proliferating cells. CHK1 gene deletion is embryonically lethal, and Chk1 inhibition in replicating cells...
Blotting Western Cell Line Tumor Cell Survival Checkpoint Kinase 1 Comet Assay DNA DNA Breaks Double-Stranded DNA Damage DNA Repair DNA Replication DNA-Binding Proteins Endodeoxyribonucleases Endonucleases Enzyme Activation Enzyme Inhibitors Humans Nucleic Acid Conformation Protein Kinases RNA Interference S Phase Thiophenes Urea
NAFlex
Adam Hospital, Ignacio Faustino, Rosana Collepardo-Guevara, Carlos González, Josep Lluis Gelpí, Modesto Orozco
Mar 25, 2021
We present NAFlex, a new web tool to study the flexibility of nucleic acids, either isolated or bound to other molecules. The server allows the user to incorporate structures from protein data banks, completing gaps and removing...
Temporal trends in leisure-time sedentary behavior among adolescents aged 12-15 years from 26 countries in Asia, Africa, and the Americas
Mireia Felez-Nobrega, Lauren B. Raine, Josep Maria Haro, Katrien Wijndaele, Ai Koyanagi
Aug 12, 2021
Abstract: Background: Multi-country studies examining trends in sedentary behaviors among adolescents have mainly focused on high-income or Western countries, and almost no data exists for the rest of the world. Thus, this study...
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Massimo F Piepoli, Arno W Hoes, Stefan Agewall, Christian Albus, Carlos Brotons, Alberico L Catapano, Marie-Therese Cooney, Ugo Corrà, Bernard Cosyns, Christi Deaton, Ian Graham, Michael Stephen Hall, FD Richard Hobbs, Maja-Lisa Løchen, Herbert Löllgen, Pedro Marques-Vidal, Joep Perk, Eva Prescott, Josep Redon, Dimitrios J Richter, Naveed Sattar, Yvo Smulders, Monica Tiberi, H Bart van der Worp, Ineke van Dis, WM Monique Verschuren, Simone Binno, ESC Scientific Document Group
May 24, 2016
blood pressure Clinical settings Diabetes Guidelines Healthy lifestyle Lipid Nutrition physical activity POPULATION Prevention PRIMARY CARE Psychosocial factors Rehabilitation Risk Assessment risk management Smoking Stakeholder Adult Age Factors Aged Antihypertensive Agents Biomarkers Cardiac Rehabilitation Cardiovascular Diseases Cost-Benefit Analysis Diabetic Angiopathies Diagnostic Imaging Diet Healthy Exercise General Practice Health Promotion Healthy Lifestyle Humans Hyperlipidemias Hypertension Middle Aged Multiple Chronic Conditions Pedigree Practice Patterns Physicians' Risk Assessment Sex Factors Smoking Cessation Socioeconomic Factors
Pigment patterns in adult fish result from superimposition of two largely independent pigmentation mechanisms
Dorso-ventral pigment pattern differences are the most widespread pigmentary adaptations in vertebrates. In mammals, this pattern is controlled by regulating melanin chemistry in melanocytes using a protein, agouti-signalling...
Temporal trends in leisure-time sedentary behavior among adolescents aged 12-15 years from 26 countries in Asia, Africa, and the Americas
Mireia Felez-Nobrega, Lauren B. Raine, Josep Maria Haro, Katrien Wijndaele, Ai Koyanagi
Aug 12, 2020
Abstract: Background: Multi-country studies examining trends in sedentary behaviors among adolescents have mainly focused on high-income or Western countries, and almost no data exists for the rest of the world. Thus, this study...
Disentangling α and β relaxation in orientationally disordered crystals with theory and experiments.
We use a microscopically motivated generalized Langevin equation (GLE) approach to link the vibrational density of states (VDOS) to the dielectric response of orientational glasses (OGs). The dielectric function calculated based...
Short-chain reactive probes as tools to unravel the Pseudomonas aeruginosa quorum sensing regulon.
In recent years, the world has seen a troubling increase in antibiotic resistance among bacterial pathogens. In order to provide alternative strategies to combat bacterial infections, it is crucial deepen our understanding into...
ALEPH
Ana Medina, Josep Triviño, Rafael J Borges, Claudia Millán, Isabel Usón, Massimo D Sammito
Apr 05, 2020
The analysis of large structural databases reveals general features and relationships among proteins, providing useful insight. A different approach is required to characterize ubiquitous secondary-structure elements, where...
Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation.
Laura Cal, Paula Suarez-Bregua, Pilar Comesana, Jennifer Owen, Ingo Braasch, Robert N. Kelsh, Jose Cerda-Reverter, Josep Rotllant
Dec 01, 2019
Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in shading by driving a switch...
Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation.
Laura Cal, Paula Suarez-Bregua, Pilar Comesana, Jennifer Owen, Ingo Braasch, Robert N. Kelsh, Jose Cerda-Reverter, Josep Rotllant
Dec 01, 2019
Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in shading by driving a switch...
Detection of functional protein domains by unbiased genome-wide forward genetic screening.
Mareike Herzog, Fabio Puddu, Julia Coates, Nicola Geisler, Josep V Forment, Stephen P Jackson
Aug 03, 2018
Establishing genetic and chemo-genetic interactions has played key roles in elucidating mechanisms by which certain chemicals perturb cellular functions. In contrast to gene disruption/depletion strategies to identify mechanisms...
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