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Loss-of-function mutations in the melanocortin 1 receptor cause disruption of dorso-ventral countershading in teleost fish
Laura Cal, Paula Suarez-Bregua, Ingo Braasch, Uwe Irion, Robert Kelsh, Jose Miguel Cerdá-Reverter, Josep Rotllant
Nov 01, 2019
The melanocortin 1 receptor (MC1R) is the central melanocortin receptor involved in vertebrate pigmentation. Mutations in this gene cause variations in coat coloration in amniotes. Additionally, in mammals MC1R is the main...
Loss-of-function mutations in the melanocortin 1 receptor cause disruption of dorso-ventral countershading in teleost fish
Laura Cal, Paula Suarez-Bregua, Ingo Braasch, Uwe Irion, Robert Kelsh, Jose Miguel Cerdá-Reverter, Josep Rotllant
Nov 01, 2019
The melanocortin 1 receptor (MC1R) is the central melanocortin receptor involved in vertebrate pigmentation. Mutations in this gene cause variations in coat coloration in amniotes. Additionally, in mammals MC1R is the main...
Poets in the Classroom
About the Poets:
Laurie Ann Guerrero is the author of Tongue in the Mouth of the Dying (University of Notre Dame Press 2013) and A Crown for Gumecindo (Aztlan Libre Press 2015). Her latest collection, I Have Eaten the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Poets in the Classroom
About the Poets:
Laurie Ann Guerrero is the author of Tongue in the Mouth of the Dying (University of Notre Dame Press 2013) and A Crown for Gumecindo (Aztlan Libre Press 2015). Her latest collection, I Have Eaten the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Poets in the Classroom
About the Poets:
Laurie Ann Guerrero is the author of Tongue in the Mouth of the Dying (University of Notre Dame Press 2013) and A Crown for Gumecindo (Aztlan Libre Press 2015). Her latest collection, I Have Eaten the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Pigment patterns in adult fish result from superimposition of two largely independent pigmentation mechanisms
Dorso-ventral pigment pattern differences are the most widespread pigmentary adaptations in vertebrates. In mammals, this pattern is controlled by regulating melanin chemistry in melanocytes using a protein, agouti-signalling...
Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation.
Laura Cal, Paula Suarez-Bregua, Pilar Comesana, Jennifer Owen, Ingo Braasch, Robert N. Kelsh, Jose Cerda-Reverter, Josep Rotllant
Dec 01, 2019
Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in shading by driving a switch...
Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation.
Laura Cal, Paula Suarez-Bregua, Pilar Comesana, Jennifer Owen, Ingo Braasch, Robert N. Kelsh, Jose Cerda-Reverter, Josep Rotllant
Dec 01, 2019
Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in shading by driving a switch...
Pigment patterns in adult fish result from superimposition of two largely independent pigmentation mechanisms
Dorso-ventral pigment pattern differences are the most widespread pigmentary adaptations in vertebrates. In mammals, this pattern is controlled by regulating melanin chemistry in melanocytes using a protein, agouti-signalling...
Extracellular Electrophysiology in the Prostate Cancer Cell Model PC-3
Miguel Cabello, Haobo Ge, Carmen Aracil, Despina Moschou, Pedro Estrela, Jose Manuel Quero, Sofia Pascu, Paulo Rocha
Jan 01, 2019
Although prostate cancer is one of the most common cancers in the male population, its basic biological function at a cellular level remains to be fully understood. This lack of in depth understanding of its physiology...
Light quark Yukawas in triboson final states
Adam Falkowski, Sanmay Ganguly, Phillippe Gras, Jose Miguel No, Kohsaku Tobioka, Natascia Vignaroli, Tevong You
May 04, 2021
Abstract: Triple heavy vector boson production, pp → VVV (V = W, Z), has recently been observed for the first time. We propose that precision measurements of this process provide an excellent probe of the first generation light...
Light quark Yukawas in triboson final states
Adam Falkowski, Sanmay Ganguly, Phillippe Gras, Jose Miguel No, Kohsaku Tobioka, Natascia Vignaroli, Tevong You
Apr 06, 2021
Abstract: Triple heavy vector boson production, pp → VVV (V = W, Z), has recently been observed for the first time. We propose that precision measurements of this process provide an excellent probe of the first generation light...
Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation.
Alejandro Carrillo-Jimenez, Mar Puigdellívol, Anna Vilalta, Jose Luis Venero, Guy Charles Brown, Peter StGeorge-Hyslop, Miguel Angel Burguillos
Nov 22, 2018
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer's disease (AD). The use of primary microglial cell cultures has proved to be a valuable...
Extracellular Electrophysiology in the Prostate Cancer Cell Model PC-3
Miguel Cabello, Haobo Ge, Carmen Aracil, Despina Moschou, Pedro Estrela, Jose Manuel Quero, Sofia Pascu, Paulo Rocha
Jan 01, 2019
Although prostate cancer is one of the most common cancers in the male population, its basic biological function at a cellular level remains to be fully understood. This lack of in depth understanding of its physiology...
Light quark Yukawas in triboson final states
Abstract
Triple heavy vector boson production, pp → VVV (V = W, Z ), has...
Adam Falkowski, Sanmay Ganguly, Phillippe Gras, Jose Miguel No, Kohsaku Tobioka, Natascia Vignaroli, Tevong You
Jul 28, 2021
The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance
Andrea Coppa, Sanjib Guha, Stéphane Fourcade, Janani Parameswaran, Montserrat Ruiz, Ann B Moser, Agatha Schlüter, Michael P Murphy, Jose Miguel Lizcano, Antonio Miranda-Vizuete, Esther Dalfó, Aurora Pujol
Feb 18, 2020
Adrenoleukodystrophy is a neurometabolic disorder caused by a defective peroxisomal ABCD1 transporter of very long-chain fatty acids (VLCFAs). Its pathogenesis is incompletely understood. Here we characterize a nematode model of...
Axonal degeneration Hypodermis Lipid Droplets Mitochondria redox imbalance Peroxisomes X-linked adrenoleukodystrophy ATP Binding Cassette Transporter Subfamily D Member 1 ATP-Binding Cassette Transporters Adrenoleukodystrophy Animals Caenorhabditis elegans Fatty Acids Mice Mice Knockout Subcutaneous Tissue
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer
Silvana Mouron, Luis Manso, Eduardo Caleiras, Jose L. Rodriguez-Peralto, Oscar M. Rueda, Carlos Caldas, Ramon Colomer, Miguel Quintela-Fandino, Maria J. Bueno
Feb 13, 2021
Abstract: Background: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their...
Hydrodynamic assembly of two-dimensional layered double hydroxide nanostructures.
Formation mechanisms of two-dimensional nanostructures in wet syntheses are poorly understood. Even more enigmatic is the influence of hydrodynamic forces. Here we use liquid flow cell transmission electron microscopy to show...
Electronic Docket Adoption in Rural Police Stations
The adoption of electronic record management systems in rural policing presents significant challenges, impacting case management and service delivery. This study investigates the barriers hindering the implementation of...
Published by: IGI Global Scientific Publishing
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer
Silvana Mouron, Luis Manso, Eduardo Caleiras, Jose L Rodriguez-Peralto, Oscar M Rueda, Carlos Caldas, Ramon Colomer, Miguel Quintela-Fandino, Maria J Bueno
Apr 09, 2021
BACKGROUND: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their distribution...
FGFR1 amplification FGFR1 overexpression Luminal breast cancer palbociclib Rogaratinib Adult Aged Aged 80 and over Antineoplastic Agents Biomarkers Tumor Breast Neoplasms Cell Line Tumor Cyclin-Dependent Kinase 4 Cyclin-Dependent Kinase 6 Disease Management Disease Susceptibility Drug Resistance Multiple Drug Resistance Neoplasm Female Gene Amplification Gene Expression Humans In Situ Hybridization Fluorescence Middle Aged Molecular Targeted Therapy Neoplasm Staging Prognosis RNA Messenger Receptor Fibroblast Growth Factor Type 1 Receptors Estrogen Treatment Outcome Young Adult
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