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Evaluation of Label-Free Confocal Raman Microspectroscopy for Monitoring Oxidative Stress In Vitro in Live Human Cancer Cells
Understanding the impact of free radicals and antioxidants in cell biology is vital; however, noninvasive nonperturbative imaging of oxidative stress remains a challenge. Here, we evaluated the ability of label-free...
Raman micro-spectroscopy for accurate identification of primary human bronchial epithelial cells.
Jakub M Surmacki, Benjamin J Woodhams, Alexandria Haslehurst, Bruce AJ Ponder, Sarah E Bohndiek
Nov 05, 2018
Live cell Raman micro-spectroscopy is emerging as a promising bioanalytical technique for label-free discrimination of a range of different cell types (e.g. cancer cells and fibroblasts) and behaviors (e.g. apoptosis). The aim...
Graphitic and oxidised high pressure high temperature (HPHT) nanodiamonds induce differential biological responses in breast cancer cell lines.
Benjamin Woodhams, Laura Ansel-Bollepalli, Jakub Surmacki, Helena Knowles, Laura Maggini, Michael De Volder, Mete Atatüre, Sarah Bohndiek
Sep 26, 2018
Nanodiamonds have demonstrated potential as powerful sensors in biomedicine, however, their translation into routine use requires a comprehensive understanding of their effect on the biological system being interrogated. Under...
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets
Nikola Dolezalova, Anja Gruszczyk, Kerry Barkan, John A. Gamble, Sam Galvin, Till Moreth, Kevin O’Holleran, Krishnaa T. Mahbubani, Jackie A. Higgins, Fiona M. Gribble, Frank Reimann, Jakub Surmacki, Simon Andrews, John J. Casey, Francesco Pampaloni, Michael P. Murphy, Graham Ladds, Nigel K. H. Slater, Kourosh Saeb-Parsy
May 20, 2021
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets.
Nikola Dolezalova, Anja Gruszczyk, Kerry Barkan, John A Gamble, Sam Galvin, Till Moreth, Kevin O'Holleran, Krishnaa T Mahbubani, Jackie A Higgins, Fiona M Gribble, Frank Reimann, Jakub Surmacki, Simon Andrews, John J Casey, Francesco Pampaloni, Michael P Murphy, Graham Ladds, Nigel Kh Slater, Kourosh Saeb-Parsy
May 24, 2021
Cryopreservation offers the potential to increase the availability of pancreatic islets for treatment of diabetic patients. However, current protocols, which use dimethyl sulfoxide (DMSO), lead to poor cryosurvival of islets. We...
The boostless bootstrap and BCFW momentum shifts
In a recent paper [1], three-particle interactions without invariance under
Lorentz boosts were constrained by demanding that they yield tree-level
four-particle scattering amplitudes with singularities as dictated by...
Two-loop leading colour helicity amplitudes for W ± γ + j production at the LHC
Abstract: We present the two-loop leading colour QCD helicity amplitudes for the process pp → W (→ lν)γ + j. We implement a complete reduction of the amplitudes, including the leptonic decay of the W-boson, using finite field...
Regular Article - Theoretical Physics Higher-Order Perturbative Calculations scattering amplitudes Specific QCD Phenomenology
Published by: Springer Berlin Heidelberg
Supply chain networks, trade and the Brexit deal
We develop a multi-country general equilibrium model featuring (i) migration flows across borders; (ii) explicit supply chain networks both across sectors and across countries; (iii) services sector with a significant role in...
On graviton non-Gaussianities in the Effective Field Theory of Inflation
We derive parity-even graviton bispectra in the Effective Field Theory of Inflation (EFToI) to all orders in derivatives. Working in perturbation theory, we construct all cubic interactions that can contribute to tree-level...
Regular Article - Theoretical Physics Effective Field Theories Space-Time Symmetries Early Universe Particle Physics
Published by: Springer Berlin Heidelberg
Voltage Evolution and Electrochemical Behaviour of Soil Microbial Fuel Cells Operated in Different Quality Soils
The desire for a net-zero carbon future is a key driver for innovation in renewable energy. Amongst several emerging solutions, soil microbial fuel cells (SMFCs) pose an interesting addition as a low-cost, carbon–neutral...
The boostless bootstrap
Abstract: Poincaré invariance is a well-tested symmetry of nature and sits at the core of our description of relativistic particles and gravity. At the same time, in most systems Poincaré invariance is not a symmetry of the...
Endoscopist biopsy rate as a quality indicator for outpatient gastroscopy
Wladyslaw Januszewicz, Paulina Wieszczy, Andrzej Bialek, Katarzyna Karpinska, Jakub Szlak, Jakub Szymonik, Maciej Rupinski, Andrzej Mroz, Jaroslaw Regula, Michal F Kaminski
Nov 27, 2019
BACKGROUND AND AIMS: The diagnosis of gastric premalignant conditions (GPCs) relies on endoscopy with mucosal sampling. We hypothesized that the endoscopist biopsy rate (EBR) might constitute a quality indicator for EGD, and we...
Adenoma Adolescent Adult Aged Ambulatory Care Barrett Esophagus Biopsy Cohort Studies Duodenal Neoplasms Female Gastritis Atrophic Gastroscopy Humans Information Storage and Retrieval Logistic Models Male Metaplasia Middle Aged Multivariate Analysis Poland Precancerous Conditions Quality Indicators Health Care Retrospective Studies Squamous Intraepithelial Lesions Stomach Stomach Neoplasms Young Adult
Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy.
Traumatic brain injury (TBI) constitutes a major cause of death and long-term disability. At present, we lack methods to non-invasively track tissue biochemistry and hence select appropriate interventions for patients. We...
A mycotic aneurysm related to Salmonella Rissen infection
Abstract: Background: Salmonella species commonly causes infection in humans and on occasion leads to serious complications, such as mycotic aneurysms. Here, we present the first case reported of a patient with a mycotic...
Long-ranged correlations in large deviations of local clustering.
In systems of diffusing particles, we investigate large deviations of a time-averaged measure of clustering around one particle. We focus on biased ensembles of trajectories, which realize large-deviation events. The bias acts...
Bootstrapping large graviton non-Gaussianities
Abstract: Gravitational interferometers and cosmological observations of the cosmic microwave background offer us the prospect to probe the laws of gravity in the primordial universe. To study and interpret these datasets we...
Published by: Springer Berlin Heidelberg
Functional patient-derived cellular models for neuropsychiatric drug discovery.
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets of existing drugs and a limited understanding of functional interactions...
Voltage Evolution and Electrochemical Behaviour of Soil Microbial Fuel Cells Operated in Different Quality Soils
The desire for a net-zero carbon future is a key driver for innovation in renewable energy. Amongst several emerging solutions, soil microbial fuel cells (SMFCs) pose an interesting addition as a low-cost, carbon–neutral...
Towards effective energy harvesting from stacks of soil microbial fuel cells
The 2050 net-zero carbon target can only be achieved with renewable energy solutions that can drastically reduce carbon emissions. Soil microbial fuel cells (SMFCs) have significant potential as a low-cost and carbon-neutral...
A Systematic Review of Gamification and Its Assessment in EFL Teaching
The aim of this study is to examine the satisfaction of EFL teachers with gamification platforms as well as to investigate how EFL teachers perceive gamification and its effects on pupils' motivation and learning outcomes. Five...
Published by: IGI Global Scientific Publishing
Two-loop leading-colour QCD helicity amplitudes for Higgs boson production in association with a bottom-quark pair at the LHC
Abstract
We compute the two-loop QCD helicity amplitudes for the production of a Higgs boson in association with a bottom quark pair at a hadron collider....
Structural, Electronic and Transport Properties of Hybrid SrTiO3-Graphene and Carbon Nanoribbon Interfaces
Jakub Baran, Christopher Eames, Keisuke Takahashi, Marco Molinari, Muhammed Islam, Stephen C. Parker
Nov 14, 2017
Hybrid materials composed of different functional structural units offer the possibility of tuning both the thermal and electronic properties of a material independently. Using quantum mechanical calculations, we investigate the...
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