Search

Results: 433
Methyl-orvinol—Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome

Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional disorder of the gastrointestinal (GI) tract. The major IBS-D symptoms include diarrhea, abdominal pain and discomfort. High density of opioid...

Methyl-orvinol—Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome

Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional disorder of the gastrointestinal (GI) tract. The major IBS-D symptoms include diarrhea, abdominal pain and discomfort. High density of opioid...

The boostless bootstrap and BCFW momentum shifts
In a recent paper [1], three-particle interactions without invariance under Lorentz boosts were constrained by demanding that they yield tree-level four-particle scattering amplitudes with singularities as dictated by...
Two-loop leading colour helicity amplitudes for W ± γ + j production at the LHC
Abstract: We present the two-loop leading colour QCD helicity amplitudes for the process pp → W (→ lν)γ + j. We implement a complete reduction of the amplitudes, including the leptonic decay of the W-boson, using finite field...
Responses of bistable piezoelectric-composite energy harvester by means of recurrences

In this paper we examine the modal response of a bistable electro-mechanical energy harvesting device based on characterization of the experimental time-series. A piezoelectric element attached to a vibrating bistable...

Supply chain networks, trade and the Brexit deal

We develop a multi-country general equilibrium model featuring (i) migration flows across borders; (ii) explicit supply chain networks both across sectors and across countries; (iii) services sector with a significant role in...

On graviton non-Gaussianities in the Effective Field Theory of Inflation
We derive parity-even graviton bispectra in the Effective Field Theory of Inflation (EFToI) to all orders in derivatives. Working in perturbation theory, we construct all cubic interactions that can contribute to tree-level...
Voltage Evolution and Electrochemical Behaviour of Soil Microbial Fuel Cells Operated in Different Quality Soils
The desire for a net-zero carbon future is a key driver for innovation in renewable energy. Amongst several emerging solutions, soil microbial fuel cells (SMFCs) pose an interesting addition as a low-cost, carbon–neutral...
No Influence of Musicianship on the Effect of Contralateral Stimulation on Frequency Selectivity.
The efferent system may control the gain of the cochlea and thereby influence frequency selectivity. This effect can be assessed using contralateral stimulation (CS) applied to the ear opposite to that used to assess frequency...
Intra-urban variability of the intake fraction from multiple emission sources.
BACKGROUND: Ambient air pollution and associated adverse health effects are among most acute environmental problems in many cities worldwide. The intake fraction (iF) approach can be applied for evaluating the health benefits of...
The boostless bootstrap
Abstract: Poincaré invariance is a well-tested symmetry of nature and sits at the core of our description of relativistic particles and gravity. At the same time, in most systems Poincaré invariance is not a symmetry of the...
A mycotic aneurysm related to Salmonella Rissen infection
Abstract: Background: Salmonella species commonly causes infection in humans and on occasion leads to serious complications, such as mycotic aneurysms. Here, we present the first case reported of a patient with a mycotic...
Long-ranged correlations in large deviations of local clustering.
In systems of diffusing particles, we investigate large deviations of a time-averaged measure of clustering around one particle. We focus on biased ensembles of trajectories, which realize large-deviation events. The bias acts...
Bootstrapping large graviton non-Gaussianities
Abstract: Gravitational interferometers and cosmological observations of the cosmic microwave background offer us the prospect to probe the laws of gravity in the primordial universe. To study and interpret these datasets we...
Functional patient-derived cellular models for neuropsychiatric drug discovery.
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets of existing drugs and a limited understanding of functional interactions...

|<

<

1

2

3

4

5

>

>|