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Antibiotic Therapy and the Gut Microbiome
Stephen A Kelly, Jonathan Nzakizwanayo, Aoife M Rodgers, Li Zhao, Rebecca Weiser, Ismaiel A Tekko, Helen O McCarthy, Rebecca J Ingram, Brian V Jones, Ryan F Donnelly, Brendan F Gilmore
May 14, 2021
The contribution of the gut microbiome to human health has long been established, with normal gut microbiota conferring protection against invasive pathogens. Antibiotics can disrupt the microbial balance of the gut...
Antibiotic Therapy and the Gut Microbiome
Stephen A Kelly, Jonathan Nzakizwanayo, Aoife M Rodgers, Li Zhao, Rebecca Weiser, Ismaiel A Tekko, Helen O McCarthy, Rebecca J Ingram, Brian V Jones, Ryan F Donnelly, Brendan F Gilmore
May 14, 2021
The contribution of the gut microbiome to human health has long been established, with normal gut microbiota conferring protection against invasive pathogens. Antibiotics can disrupt the microbial balance of the gut...
Philip McShane
Ivo Coelho
Mar 16, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Dialectic Exercise on *Method in Theology,* Chapter 5
Ivo Coelho
Nov 12, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Dialectic Exercise on *Method in Theology,* Chapter 5
Ivo Coelho
Nov 12, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Philip McShane
Ivo Coelho
Mar 16, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Gut Hormone Regulation and Secretion via FFA1 and FFA4.
The digestion, absorption and utilisation of dietary triglycerides are controlled by gut hormones, released from enteroendocrine cells along the length of the gastrointestinal tract. Major players in the detection of ingested...
Information recovery from low coverage whole-genome bisulfite sequencing.
Emanuele Libertini, Simon C Heath, Rifat A Hamoudi, Marta Gut, Michael J Ziller, Agata Czyz, Victor Ruotti, Hendrik G Stunnenberg, Mattia Frontini, Willem H Ouwehand, Alexander Meissner, Ivo G Gut, Stephan Beck
Sep 08, 2018
The cost of whole-genome bisulfite sequencing (WGBS) remains a bottleneck for many studies and it is therefore imperative to extract as much information as possible from a given dataset. This is particularly important because...
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models.
Alba Cortés, Simon Clare, Alice Costain, Alexandre Almeida, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, James Rooney, Matthew Berriman, Trevor Lawley, Andrew S MacDonald, Gabriel Rinaldi, Cinzia Cantacessi
Oct 22, 2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are...
Schistosoma mansoni Dysbiosis gut microbial diversity helminth-gut microbiota interactions human-microbiota associated mouse models immune-modulation Animals Antibodies Protozoan Bacteria Biodiversity Computational Biology Disease Models Animal Dysbiosis Feces Gastrointestinal Microbiome host-parasite interactions immunomodulation Metagenomics Mice Parasite Load RNA Ribosomal 16S Schistosoma Schistosomiasis mansoni
Nutrient-Induced Cellular Mechanisms of Gut Hormone Secretion.
The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the enteroendocrine cells, trigger the release...
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models
Alba Cortés, Simon Clare, Alice Costain, Alexandre Almeida, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, James Rooney, Matthew Berriman, Trevor Lawley, Andrew S. MacDonald, Gabriel Rinaldi, Cinzia Cantacessi
Dec 02, 2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are...
Response of the human gut and saliva microbiome to urbanization in Cameroon.
Ana Lokmer, Sophie Aflalo, Norbert Amougou, Sophie Lafosse, Alain Froment, Francis Ekwin Tabe, Mathilde Poyet, Mathieu Groussin, Rihlat Said-Mohamed, Laure Ségurel
May 18, 2020
Urban populations from highly industrialized countries are characterized by a lower gut bacterial diversity as well as by changes in composition compared to rural populations from less industrialized countries. To unveil the...
Nutrient-Induced Cellular Mechanisms of Gut Hormone Secretion
The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the enteroendocrine cells, trigger the release...
Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Carmen Rubio, Marta Puerto, Juan J García-Rodríquez, Van B Lu, Irma García-Martínez, Rosa Alén, Patricia Sanmartín-Salinas, M Val Toledo-Lobo, Jorge Saiz, Javier Ruperez, Coral Barbas, Luis Menchén, Fiona M Gribble, Frank Reimann, Luis G Guijarro, Jose M Carrascosa, Ángela M Valverde
May 05, 2020
OBJECTIVE:Non-alcoholic steatohepatitis (NASH) is characterized by a robust pro-inflammatory component at both hepatic and systemic levels together with a disease-specific gut microbiome signature. Protein tyrosine phosphatase...
Published by: Molecular metabolism
Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats.
Circadian rhythms in gut microbiota composition are crucial for metabolic function, yet the extent to which they govern microbial dynamics compared to seasonal and lifetime processes remains unknown. Here, we investigate gut...
Diet induces parallel changes to the gut microbiota and problem solving performance in a wild bird
Gabrielle L. Davidson, Niamh Wiley, Amy C. Cooke, Crystal N. Johnson, Fiona Fouhy, Michael S. Reichert, Iván de la Hera, Jodie M. S. Crane, Ipek G. Kulahci, R. Paul Ross, Catherine Stanton, John L. Quinn
Nov 27, 2020
Abstract: The microbial community in the gut is influenced by environmental factors, especially diet, which can moderate host behaviour through the microbiome-gut-brain axis. However, the ecological relevance of...
Significance of the Gut Microbiome for Viral Diarrheal and Extra-Intestinal Diseases
Ulrich Desselberger
Aug 14, 2021
The composition of the mammalian gut microbiome is very important for the health and disease of the host. Significant correlations of particular gut microbiota with host immune responsiveness and various infectious and...
Significance of the Gut Microbiome for Viral Diarrheal and Extra-Intestinal Diseases.
Ulrich Desselberger
Sep 28, 2021
The composition of the mammalian gut microbiome is very important for the health and disease of the host. Significant correlations of particular gut microbiota with host immune responsiveness and various infectious and...
antiviral immune responses Diet gut disease gut microbiome microbial metabolites microbiome transplantation microbiome–host relationship noninfectious disease Prebiotics Probiotics Animals Bacteria Bacterial Physiological Phenomena Diarrhea Diet Dysbiosis Gastrointestinal Microbiome Host Microbial Interactions Humans Intestines Mice Prebiotics Probiotics
A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children
Dora Ia Pereira, Nuredin I Mohammed, Ogochukwu Ofordile, Famalang Camara, Bakary Baldeh, Thomas Mendy, Chilel Sanyang, Amadou T Jallow, Ilias Hossain, James Wason, Andrew M Prentice
Dec 17, 2018
Background: Iron deficiency and its associated anaemia (IDA) are the leading forms of micronutrient malnutrition worldwide. Here we describe the rationale and design of the first clinical trial evaluating the efficacy and safety...
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
David T. Riglar, David L. Richmond, Laurent Potvin-Trottier, Andrew A. Verdegaal, Alexander D. Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena G. Lyon, Johan Paulsson, Pamela A. Silver
Oct 10, 2020
Abstract: Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in engineered cells. Such oscillators have been refined in bacteria in vitro, however, these systems have lacked the...
Interference with the lower gut-liver axis induces remission of primary sclerosing cholangitis in a patient with ulcerative colitis.
John Ong, Leila Mebarek, Michael Bath, Carla Swift, Babur Javaid, Jenish Patel, Yasseen Al-Naeeb
Mar 17, 2020
The gut-liver axis describes the complex interactions between gut microbiota, the small and large bowel, the immune system and the liver. Current evidence associates abnormalities within the gut-liver axis with liver disease...
Gut Reaction
Chronic gastrointestinal (GI) tract conditions, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are common conditions associated with disordered bowel movements and significant pain. However...
Maternal gut microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice.
Jorge Lopez-Tello, Zoe Schofield, Raymond Kiu, Matthew J Dalby, Douwe van Sinderen, Gwénaëlle Le Gall, Amanda N Sferruzzi-Perri, Lindsay J Hall
Aug 04, 2022
The gut microbiota plays a central role in regulating host metabolism. While substantial progress has been made in discerning how the microbiota influences host functions post birth and beyond, little is known about how key...
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator.
David T Riglar, David L Richmond, Laurent Potvin-Trottier, Andrew A Verdegaal, Alexander D Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena G Lyon, Johan Paulsson, Pamela A Silver
Dec 11, 2019
Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in engineered cells. Such oscillators have been refined in bacteria in vitro, however, these systems have lacked the...
The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases
Fengzhe Xu, Yuanqing Fu, Ting-yu Sun, Zengliang Jiang, Zelei Miao, Menglei Shuai, Wanglong Gou, Chu-wen Ling, Jian Yang, Jun Wang, Yu-ming Chen, Ju-Sheng Zheng
Oct 08, 2020
Abstract: Background: Interest in the interplay between host genetics and the gut microbiome in complex human diseases is increasing, with prior evidence mainly being derived from animal models. In addition, the shared and...
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