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Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors
Daniel Blanco Melo
Jan 01, 0001
About 8 and 10 percent of the human and mouse genomes, respectively, are comprised of sequences of retroviral origin. Occasional infection of germ line can lead to integrated retroviral genomes being vertically inherited as host...
Published by: Rockefeller University
Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome
Chrystelle Colas, Sjaak Pouwels, Nicoline Hoogerbrugge, Tanya Bisseling, Virginie Bubien, Frederic Caux, Nathalie Chabbert-Buffet, Sophie Da Mota Gomes, Martin Gotthardt, Marleen Kets, Katherine L. Lachlan, Thera P. Links, Michel Longy, Ritse Mann, Leo Schultze Kool, Robert K. Semple, Ian Stock, Marc Tischkowitz, Janet Vos, Marjolijn Ligtenberg, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Carla Oliveira, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Feb 09, 2021
Abstract: PTEN hamartoma tumour syndrome is a diverse multi-system disorder predisposing to the development of hamartomatous growths, increasing risk of breast, thyroid, renal cancer, and possibly increasing risk of endometrial...
Guidelines for the Li–Fraumeni and heritable TP53 -related cancer syndromes
Svetlana Bajalica Lagercrantz, Carla Oliveira, Rita Magenheim, D. Gareth Evans, Nicoline Hoogerbrugge, Marjolijn Ligtenberg, Marleen Kets, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Marc Tischkowitz, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Chrystelle Colas, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Feb 09, 2021
Abstract: Fifty years after the recognition of the Li–Fraumeni syndrome (LFS), our perception of cancers related to germline alterations of TP53 has drastically changed: (i) germline TP53 alterations are often identified among...
Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome
Chrystelle Colas, Sjaak Pouwels, Nicoline Hoogerbrugge, Tanya Bisseling, Virginie Bubien, Frederic Caux, Nathalie Chabbert-Buffet, Sophie Da Mota Gomes, Martin Gotthardt, Marleen Kets, Katherine L. Lachlan, Thera P. Links, Michel Longy, Ritse Mann, Leo Schultze Kool, Robert K. Semple, Ian Stock, Marc Tischkowitz, Janet Vos, Marjolijn Ligtenberg, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Carla Oliveira, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Jun 12, 2021
Abstract: PTEN hamartoma tumour syndrome is a diverse multi-system disorder predisposing to the development of hamartomatous growths, increasing risk of breast, thyroid, renal cancer, and possibly increasing risk of endometrial...
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G. Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T. Rubio, Aleix Prat, Carlos Caldas
Jun 07, 2021
Abstract: The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to...
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers.
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T Rubio, Aleix Prat, Carlos Caldas
Jul 26, 2021
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to therapy. Here...
Mitochondrial DNA heteroplasmy in cardiac tissue from individuals with and without coronary artery disease
The cellular environment associated with coronary artery disease (CAD) can lead to mitochondrial DNA (mtDNA) damage. Mitochondrial variants in some copies of mtDNA (heteroplasmy) and mtDNA content are potential genetic...
Coronary Artery Disease Mitochondrial DNA heteroplasmy mitochondrial variation Mitochondria Cardiovascular Diseases Genetic Structures
Published by: Harrisburg University of Science and Technology
Exploding Chemical Gardens
Yang Ding, Carlos M Gutiérrez-Ariza, C Ignacio Sainz-Díaz, Julyan HE Cartwright, Silvana SS Cardoso
May 03, 2019
Chemical gardens and clock reactions are two of the best-known demonstration reactions in chemistry. Until now these have been separate categories. We have discovered that a chemical garden confined to two dimensions is a clock...
Technique of Classification, Organization, Creation, and Use of Collective Knowledge
During the teaching of a subject, engineering in this particular case, students acquire knowledge through different learning activities that are guided by the teaching staff. In this process, students work with the resources and...
Published by: IGI Global Scientific Publishing
Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome
Chrystelle Colas, Sjaak Pouwels, Nicoline Hoogerbrugge, Tanya Bisseling, Virginie Bubien, Frederic Caux, Nathalie Chabbert-Buffet, Sophie Da Mota Gomes, Martin Gotthardt, Marleen Kets, Katherine L. Lachlan, Thera P. Links, Michel Longy, Ritse Mann, Leo Schultze Kool, Robert K. Semple, Ian Stock, Marc Tischkowitz, Janet Vos, Marjolijn Ligtenberg, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Carla Oliveira, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Sep 23, 2020
Abstract: PTEN hamartoma tumour syndrome is a diverse multi-system disorder predisposing to the development of hamartomatous growths, increasing risk of breast, thyroid, renal cancer, and possibly increasing risk of endometrial...
Guidelines for the Li–Fraumeni and heritable TP53 -related cancer syndromes
Svetlana Bajalica Lagercrantz, Carla Oliveira, Rita Magenheim, D. Gareth Evans, Nicoline Hoogerbrugge, Marjolijn Ligtenberg, Marleen Kets, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Marc Tischkowitz, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Chrystelle Colas, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Sep 23, 2020
Abstract: Fifty years after the recognition of the Li–Fraumeni syndrome (LFS), our perception of cancers related to germline alterations of TP53 has drastically changed: (i) germline TP53 alterations are often identified among...
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers.
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T Rubio, Aleix Prat, Carlos Caldas
Jul 28, 2021
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to therapy. Here...
Published by: NPJ breast cancer
Rain Garden Maintenance Guide
Hannah Blanco
Jan 01, 0001
Gardens, while serving an aesthetic purpose, also have practical and ecological importance. They provide food and habitat for local pollinators and wildlife, and, in the case of the rain garden, perform the important task of...
Published by: Ursinus College
RápidoPGS
MOTIVATION: Polygenic scores (PGS) aim to genetically predict complex traits at an individual level. PGS are typically trained on genome-wide association summary statistics and require an independent test dataset to tune...
A Global Tug of War
Micro-businesses are the lifeblood of any functioning economy: they are more numerous and, collectively, have a higher turnover than any other form of business in the majority of countries around the globe. In all parts of the...
Explaining gender differences in turnout using panel data across elections
Objectives: The current study offers the first systematic analysis of the impact of citizens’ interest in and perceptions of specific elections on gender differences in turnout. Methods: Using an Internet panel survey conducted...
Ludwig Landgrebe’s Phenomenology of Moods
Ignacio Quepons
Apr 21, 2021
In a letter dated February 5, 1933, Husserl shares his disagreements over anattempt to connect the notion of the horizon with the Heideggerian philosophy ofmoods with Landgrebe. Husserl claims that for him, moods are founded in...
Published by: Memorial University of Newfoundland
Anthracycline-Related Cardiotoxicity in Patients with Acute Myeloid Leukemia and Down Syndrome: A Literature Review
Pediatric patients with Down syndrome (DS) are at an increased risk of developing certain cancers. Specifically, patients with DS have a reported 10-20-fold increased risk of developing acute myeloid leukemia (AML)....
anthracycline Cardiotoxicity Pediatric AML Leukemia Down Syndrome Doxorubicin Chemicals and Drugs Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Published by: Harrisburg University of Science and Technology
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