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Manipulation of the unfolded protein response
Liliana Echavarría-Consuegra, Georgia M Cook, Idoia Busnadiego, Charlotte Lefèvre, Sarah Keep, Katherine Brown, Nicole Doyle, Giulia Dowgier, Krzysztof Franaszek, Nathan A Moore, Stuart G Siddell, Erica Bickerton, Benjamin G Hale, Andrew E Firth, Ian Brierley, Nerea Irigoyen
Aug 09, 2021
Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins in the endoplasmic reticulum (ER) due to high ER load. We have used RNA...
Activating Transcription Factor 6 Animals Antiviral Agents Cell Line Chlorocebus aethiops Drug Delivery Systems Endoribonucleases HEK293 Cells Humans Mice Murine hepatitis virus Protein Serine-Threonine Kinases RNA-seq Unfolded Protein Response Vero Cells Viral Proteins Virus Replication COVID-19 Drug Treatment
Manipulation of the unfolded protein response
Liliana Echavarría-Consuegra, Georgia M Cook, Idoia Busnadiego, Charlotte Lefèvre, Sarah Keep, Katherine Brown, Nicole Doyle, Giulia Dowgier, Krzysztof Franaszek, Nathan A Moore, Stuart G Siddell, Erica Bickerton, Benjamin G Hale, Andrew E Firth, Ian Brierley, Nerea Irigoyen
Jul 28, 2021
Cell Line Vero Cells Animals Humans Mice Murine hepatitis virus Endoribonucleases Protein-Serine-Threonine Kinases Viral Proteins Antiviral Agents Drug Delivery Systems Virus Replication Activating Transcription Factor 6 Unfolded Protein Response HEK293 Cells RNA-seq Chlorocebus aethiops covid-19
Published by: PLoS pathogens
Manipulation of the unfolded protein response
Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
Katherine M Wilson, Eszter Katona, Idoia Glaria, Mireia Carcolé, Imogen J Swift, Aitana Sogorb-Esteve, Carolin Heller, Arabella Bouzigues, Amanda J Heslegrave, Ashvini Keshavan, Kathryn Knowles, Saurabh Patil, Susovan Mohapatra, Yuanjing Liu, Jaya Goyal, Raquel Sanchez-Valle, Robert Jr Laforce, Matthis Synofzik, James B Rowe, Elizabeth Finger, Rik Vandenberghe, Christopher R Butler, Alexander Gerhard, John C van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Alexandre de Mendonça, Mario Masellis, M Carmela Tartaglia, Markus Otto, Caroline Graff, Simon Ducharme, Jonathan M Schott, Andrea Malaspina, Henrik Zetterberg, Ramakrishna Boyanapalli, Jonathan D Rohrer, Adrian M Isaacs, Genetic FTD Initiative (GENFI)
Apr 07, 2022