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Validation of the Dominant Sequence Paradigm and Role of Dynamic Contrast-enhanced Imaging in PI-RADS Version 2.
Matthew D Greer, Joanna H Shih, Nathan Lay, Tristan Barrett, Leonardo Kayat Bittencourt, Samuel Borofsky, Ismail M Kabakus, Yan Mee Law, Jamie Marko, Haytham Shebel, Francesca V Mertan, Maria J Merino, Bradford J Wood, Peter A Pinto, Ronald M Summers, Peter L Choyke, Baris Turkbey
Sep 10, 2018
Purpose To validate the dominant pulse sequence paradigm and limited role of dynamic contrast material-enhanced magnetic resonance (MR) imaging in the Prostate Imaging Reporting and Data System (PI-RADS) version 2 for prostate...
Interreader Variability of Prostate Imaging Reporting and Data System Version 2 in Detecting and Assessing Prostate Cancer Lesions at Prostate MRI.
Matthew D Greer, Joanna H Shih, Nathan Lay, Tristan Barrett, Leonardo Bittencourt, Samuel Borofsky, Ismail Kabakus, Yan Mee Law, Jamie Marko, Haytham Shebel, Maria J Merino, Bradford J Wood, Peter A Pinto, Ronald M Summers, Peter L Choyke, Baris Turkbey
Sep 13, 2019
OBJECTIVE. The purpose of this study was to evaluate agreement among radiologists in detecting and assessing prostate cancer at multiparametric MRI using Prostate Imaging Reporting and Data System version 2 (PI-RADSv2)....
Computer-aided diagnosis prior to conventional interpretation of prostate mpMRI
Matthew D Greer, Nathan Lay, Joanna H Shih, Tristan Barrett, Leonardo Kayat Bittencourt, Samuel Borofsky, Ismail Kabakus, Yan Mee Law, Jamie Marko, Haytham Shebel, Francesca V Mertan, Maria J Merino, Bradford J Wood, Peter A Pinto, Ronald M Summers, Peter L Choyke, Baris Turkbey
Nov 05, 2018
OBJECTIVES: To evaluate if computer-aided diagnosis (CAD) prior to prostate multi-parametric MRI (mpMRI) can improve sensitivity and agreement between radiologists. METHODS: Nine radiologists (three each high, intermediate, low...
The Mediation Role of Technology Systems in the Relationship Between Education Technology Antecedents on Student Satisfaction
The purpose of this paper is to explore the influence of education technology antecedents and perceptions of usefulness and ease of use of educational technology systems on attitudes towards computer-based teaching in Egyptian...
Published by: IGI Global Scientific Publishing
Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation.
Sonia Gaur, Nathan Lay, Stephanie A Harmon, Sreya Doddakashi, Sherif Mehralivand, Burak Argun, Tristan Barrett, Sandra Bednarova, Rossanno Girometti, Ercan Karaarslan, Ali Riza Kural, Aytekin Oto, Andrei S Purysko, Tatjana Antic, Cristina Magi-Galluzzi, Yesim Saglican, Stefano Sioletic, Anne Y Warren, Leonardo Bittencourt, Jurgen J Fütterer, Rajan T Gupta, Ismail Kabakus, Yan Mee Law, Daniel J Margolis, Haytham Shebel, Antonio C Westphalen, Bradford J Wood, Peter A Pinto, Joanna H Shih, Peter L Choyke, Ronald M Summers, Baris Turkbey
Sep 27, 2018
For prostate cancer detection on prostate multiparametric MRI (mpMRI), the Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) and computer-aided diagnosis (CAD) systems aim to widely improve standardization across...
Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity.
Haytham O Tawfik, Moataz A Shaldam, Alessio Nocentini, Rofaida Salem, Hadia Almahli, Sara T Al-Rashood, Claudiu T Supuran, Wagdy M Eldehna
May 21, 2022
Carbonic anhydrases (CAs) are one of the promising targets for the development of anticancer agents. CA isoforms are implicated in various physiological processes and are expressed in both normal and cancerous cells. Thus...
Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach.
Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study.
Ahmed Abdelaal Ahmed Mahmoud M Alkhatip, Michail Georgakis, Lucio R Montero Valenzuela, Mohamed Hamza, Ehab Farag, Jaqui Hodgkinson, Hisham Hosny, Ahmed M Kamal, Mohamed Wagih, Amr Naguib, Hany Yassin, Haytham Algameel, Mohamed Elayashy, Mohamed Abdelhaq, Mohamed I Younis, Hassan Mohamed, Mohammed Abdulshafi, Mohamed A Elramely
Mar 16, 2021
SARS-CoV-2 currently lacks effective first-line drug treatment. We present promising data from in silico docking studies of new Methisazone compounds (modified with calcium, Ca; iron, Fe; magnesium, Mg; manganese, Mn; or zinc...
covid-19 SARS-CoV-2 Molecular docking prophylaxis Treatment Antiviral Agents Calcium Coronavirus 3C Proteases Coronavirus Papain-Like Proteases Coronavirus RNA-Dependent RNA Polymerase Drug Design Humans Iron Magnesium manganese Metals Methisazone Models Molecular Molecular Docking Simulation Molecular Dynamics Simulation Protein Binding SARS-CoV-2 Spike Glycoprotein Coronavirus Zinc COVID-19 Drug Treatment
Demonstrating trustworthiness when collecting and sharing genomic data
Richard Milne, Katherine I Morley, Mohamed A Almarri, Shamim Anwer, Jerome Atutornu, Elena E Baranova, Paul Bevan, Maria Cerezo, Yali Cong, Alessia Costa, Christine Critchley, Josepine Fernow, Peter Goodhand, Qurratulain Hasan, Aiko Hibino, Gry Houeland, Heidi C Howard, S Zakir Hussain, Charlotta Ingvoldstad Malmgren, Vera L Izhevskaya, Aleksandra Jędrzejak, Cao Jinhong, Megumi Kimura, Erika Kleiderman, Brandi Leach, Keying Liu, Deborah Mascalzoni, Álvaro Mendes, Jusaku Minari, Dianne Nicol, Emilia Niemiec, Christine Patch, Jack Pollard, Barbara Prainsack, Marie Rivière, Lauren Robarts, Jonathan Roberts, Virginia Romano, Haytham A Sheerah, James Smith, Alexandra Soulier, Claire Steed, Vigdis Stefànsdóttir, Cornelia Tandre, Adrian Thorogood, Torsten H Voigt, Nan Wang, Anne V West, Go Yoshizawa, Anna Middleton
Jun 27, 2021
BACKGROUND: Public trust is central to the collection of genomic and health data and the sustainability of genomic research. To merit trust, those involved in collecting and sharing data need to demonstrate they are trustworthy....
Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic
James C Glasbey, Dmitri Nepogodiev, Joana FF Simoes, Omar Omar, Elizabeth Li, Mary L Venn, Pgdme, Mohammad K Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G Edwards, Jonathan P Evans, Marco Fiore, Jose Flavio Videria, Samuel J Ford, Ian Ganly, Ewen A Griffiths, Rohan R Gujjuri, Angelos G Kolias, Haytham MA Kaafarani, Ana Minaya-Bravo, Siobhan C McKay, Helen M Mohan, Keith J Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J Smart, Grant D Stewart, Sudha Sundar Mrcog, Raghavan Vidya, Aneel A Bhangu, COVIDSurg Collaborative
Sep 03, 2020
PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical...
Demonstrating trustworthiness when collecting and sharing genomic data
Richard Milne, Katherine I. Morley, Mohamed A. Almarri, Shamim Anwer, Jerome Atutornu, Elena E. Baranova, Paul Bevan, Maria Cerezo, Yali Cong, Alessia Costa, Christine Critchley, Josepine Fernow, Peter Goodhand, Qurratulain Hasan, Aiko Hibino, Gry Houeland, Heidi C. Howard, S. Zakir Hussain, Charlotta Ingvoldstad Malmgren, Vera L. Izhevskaya, Aleksandra Jędrzejak, Cao Jinhong, Megumi Kimura, Erika Kleiderman, Brandi Leach, Keying Liu, Deborah Mascalzoni, Álvaro Mendes, Jusaku Minari, Dianne Nicol, Emilia Niemiec, Christine Patch, Jack Pollard, Barbara Prainsack, Marie Rivière, Lauren Robarts, Jonathan Roberts, Virginia Romano, Haytham A. Sheerah, James Smith, Alexandra Soulier, Claire Steed, Vigdis Stefànsdóttir, Cornelia Tandre, Adrian Thorogood, Torsten H. Voigt, Nan Wang, Anne V. West, Go Yoshizawa, Anna Middleton
May 25, 2021
Abstract: Background: Public trust is central to the collection of genomic and health data and the sustainability of genomic research. To merit trust, those involved in collecting and sharing data need to demonstrate they are...