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The Ursinus Weekly, February 3, 1919
Practice teaching and the small college Gettysburg quintette too speedy for Ursinus Opening session of the H.-P. group Ursinus trounces Washington Brotherhood of St. Paul holds meeting Campus democracy Junior girls sell...
Ursinus College Collegeville Pennsylvania newspaper Basketball YMCA YWCA Zwinglian literary society Schaff literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release.
Yue Ma, Risheka Ratnasabapathy, Ivan De Backer, Chioma Izzi-Engbeaya, Marie-Sophie Nguyen-Tu, Joyceline Cuenco, Ben Jones, Christopher D John, Brian YH Lam, Guy A Rutter, Giles SH Yeo, Waljit S Dhillo, James Gardiner
Jun 15, 2020
Glucokinase (GK) is highly expressed in the hypothalamic paraventricular nucleus (PVN); however, its role is currently unknown. We found that GK in the PVN acts as part of a glucose-sensing mechanism within the PVN that...
A graph model for imperative computation
Guy A McCusker
Jan 12, 2010
Scott's graph model is a lambda-algebra based on the observation that continuous endofunctions on the lattice of sets of natural numbers can be represented via their graphs. A graph is a relation mapping finite sets of input...
A graph model for imperative computation
Guy A McCusker
Jan 12, 2010
Scott's graph model is a lambda-algebra based on the observation that continuous endofunctions on the lattice of sets of natural numbers can be represented via their graphs. A graph is a relation mapping finite sets of input...
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells
Zijian Fang, Shiqian Chen, Yusman Manchanda, Stavroula Bitsi, Philip Pickford, Alessia David, Maria M. Shchepinova, Ivan R. Corrêa Jr, David J. Hodson, Johannes Broichhagen, Edward W. Tate, Frank Reimann, Victoria Salem, Guy A. Rutter, Tricia Tan, Stephen R. Bloom, Alejandra Tomas, Ben Jones
Nov 10, 2020
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic...
Molecules with dipoles in periodic boundary conditions in a tetragonal cell.
MJ Rutter
May 09, 2019
When a system which contains a dipole, and whose dimensionality is less than three, is studied in a code which imposes periodic boundary conditions in all three dimensions, an artificial electric field arises which keeps the...
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Zijian Fang, Shiqian Chen, Yusman Manchanda, Stavroula Bitsi, Philip Pickford, Alessia David, Maria M Shchepinova, Ivan R Corrêa, David J Hodson, Johannes Broichhagen, Edward W Tate, Frank Reimann, Victoria Salem, Guy A Rutter, Tricia Tan, Stephen R Bloom, Alejandra Tomas, Ben Jones
Jan 25, 2021
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic...
Assessment of dermal exposure to pesticide residues during re-entry
Currently, the determination of health risks to pesticide applicators from dermal exposure to these chemicals is assessed using either a concentrate of the compound or a relevant aqueous dilution. Neither of these conditions...
Regulatory Science and Innovation Programme for Europe (ReScIPE)
Philip A. Hines, Richard H. Guy, Angela Brand, Anthony J. Humphreys, Marisa Papaluca-Amati
Dec 01, 2020
Regulatory science underpins the objective evaluation of medicinal products. It is therefore imperative that regulatory science and expertise remain at the cutting edge so that innovations of ever-increasing complexity are...
Reverse iontophoresis of L-lactate
This work investigates the reverse iontophoretic extraction of lactate, a widely used marker of tissue distress in critically ill patients and of sports performance. In vitro experiments were performed to establish the...
Dermatopharmacokinetics
The dermatopharmacokinetic methodology, in which tape stripping of the stratum corneum (SC) is used to access the amount of drug accumulated in the skin barrier, has been proposed for the quantification of topical drug...
Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG)
The effect of polyethylene glycol 400 (PEG) dissolved at various concentrations (0-40% v/v) in water, on the interfacial transport of methyl nicotinate across an aqueous-isopropyl myristate interface was investigated with a...
Couple Establishes Endowed Scholarship for Political Science, Business Majors
Winthrop University
Jan 01, 0001
The Jody Guy Gaulin and Gary V. Gaulin Endowed Scholarship will support political science or business majors. The couple, who lives in Seneca, South Carolina, met at Winthrop.
Published by: Winthrop University
Mechanical tomography of human corneocytes with a nanoneedle
Atomic force microscopy (AFM) can image biological samples and characterize their mechanical properties. However, the low aspect ratio of standard AFM probes typically limits these measurements to surface properties. Here, the...
Regulatory Science and Innovation Programme for Europe (ReScIPE)
Philip A. Hines, Richard H. Guy, Angela Brand, Anthony J. Humphreys, Marisa Papaluca-Amati
Dec 01, 2020
Regulatory science underpins the objective evaluation of medicinal products. It is therefore imperative that regulatory science and expertise remain at the cutting edge so that innovations of ever-increasing complexity are...
A 3D cell shape that enables tube formation.
Guy Blanchard
Nov 15, 2018
Sheets of cells called epithelia can curve into tubes in embryos. Modelling and in vivo observations reveal that cells in the tube adopt an asymmetric cell shape dubbed scutoid, contrary to some previous assumptions.
Developing a quality culture for digital library programmes
This paper describes approaches for the development of quality assurance procedures which are needed in order to ensure that deliverables from digital library programmes will be interoperable. The adoption of open standards is...
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