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IPR Policy Brief - Climate change regulation
Regulators’ efforts to shape business responses to climate change centre on the development of CO2 markets. These are designed to deliver significant CO2 emission reductions at the lowest possible cost to industry. However, the...
Published by: University of Bath
IPR Policy Brief - Climate change regulation
Regulators’ efforts to shape business responses to climate change centre on the development of CO2 markets. These are designed to deliver significant CO2 emission reductions at the lowest possible cost to industry. However, the...
Published by: University of Bath
A mutational signature in gastric cancer suggests therapeutic strategies.
Targeting defects in the DNA repair machinery of neoplastic cells, for example, those due to inactivating BRCA1 and/or BRCA2 mutations, has been used for developing new therapies in certain types of breast, ovarian and...
Deciphering signatures of mutational processes operative in human cancer.
The genome of a cancer cell carries somatic mutations that are the cumulative consequences of the DNA damage and repair processes operative during the cellular lineage between the fertilized egg and the cancer cell. Remarkably...
A case for critical realism in the pursuit of interdisciplinarity and impact
Gareth Wiltshire
Jan 01, 0001

In recent years, much social scientific scholarship in sport, exercise and health (SEH) has repudiated (post) positivist research and has instead persuasively argued in favour of qualitative research from...

Invariable generation of permutation and linear groups
Gareth Tracey
Apr 15, 2019

A subset {x 1,x 2,…,x d} of a group G invariably generates G if {x 1 g 1 ,x 2 g 2 ,…,x d g d...

Invariable generation of permutation and linear groups
Gareth Tracey
Apr 15, 2019

A subset {x 1,x 2,…,x d} of a group G invariably generates G if {x 1 g 1 ,x 2 g 2 ,…,x d g d...

Profinite rigidity of graph manifolds, II
Gareth Wilkes
Mar 11, 2019
In this paper we study some consequences of the author's classification of graph manifolds by their profinite fundamental groups. In particular we study commensurability, the behaviour of knots, and relation to mapping classes....
Exploring the role of social capital in community-based physical activity

There is a need to address social inequalities related to health and physical activity. Taking a practice-led approach to intervention research, this paper uses the case of parkrun–a rapidly growing weekly running...

Symposium 3:The mechanisms of nutrient interactions

The objective of this review paper is to evaluate the impact of undertaking aerobic exercise in the overnight-fasted v. fed-state, in the context of optimising the health benefits of regular physical activity. Conducting a...

Rethinking validity in qualitative sport and exercise psychology research
Over the last two decades, the relativist approach has significantly shaped debates about the quality and rigour of qualitative research in sport and exercise psychology (SEP). In the absence of any published critiques of...
A case for critical realism in the pursuit of interdisciplinarity and impact
Gareth Wiltshire
Jan 01, 0001

In recent years, much social scientific scholarship in sport, exercise and health (SEH) has repudiated (post) positivist research and has instead persuasively argued in favour of qualitative research from...

Left 3-Engel elements in groups of exponent 60

Let G be a group and let x G be a left 3-Engel element of order dividing 60. Suppose furthermore that (x)G has no elements of order 8, 9 and 25. We show that x is then contained in the locally nilpotent radical of G. In...

RNA editing of human microRNAs.
BACKGROUND: MicroRNAs (miRNAs) are short RNAs of around 22 nucleotides that regulate gene expression. The primary transcripts of miRNAs contain double-stranded RNA and are therefore potential substrates for adenosine to inosine...
Recurrent histone mutations in T-cell acute lymphoblastic leukaemia.
Mutations affecting key modifiable histone type 3 (H3; Supplementary Table 1) residues are frequent oncogenic events in certain solid tumours (Feinberg, et al 2016), and have also recently been implicated in a subset of acute...
Short inverted repeats contribute to localized mutability in human somatic cells.
Selected repetitive sequences termed short inverted repeats (SIRs) have the propensity to form secondary DNA structures called hairpins. SIRs comprise palindromic arm sequences separated by short spacer sequences that form the...
Synthesis and modification of silicon-containing polymers using ultrasound
Gareth J Price
Jan 01, 0001
The application of high-intensity ultrasound to silicon backbone polymers, particularly polydimethylsiloxane and polyorganosilanes, is described. There are advantages in using ultrasound in both modifying the molecular weights...
Synthesis and modification of silicon-containing polymers using ultrasound
Gareth J Price
Jan 01, 0001
The application of high-intensity ultrasound to silicon backbone polymers, particularly polydimethylsiloxane and polyorganosilanes, is described. There are advantages in using ultrasound in both modifying the molecular weights...
Rethinking validity in qualitative sport and exercise psychology research
Over the last two decades, the relativist approach has significantly shaped debates about the quality and rigour of qualitative research in sport and exercise psychology (SEP). In the absence of any published critiques of...
Left 3-Engel elements in groups of exponent 60

Let G be a group and let x G be a left 3-Engel element of order dividing 60. Suppose furthermore that (x)G has no elements of order 8, 9 and 25. We show that x is then contained in the locally nilpotent radical of G. In...

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