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Transcriptomic and Proteomic Studies of Intercellular Communication Between Melanocytes and Keratinocytes in Human Skin
Gabriella Stephanne Spitz-Becker
Jan 01, 0001
The epidermis is a stratified epithelium composed of multiple cell types. Keratinocytes are the most prevalent cells in the epidermis and provide the barrier function of the skin. Interspersed amongst the keratinocytes in the...
Published by: Rockefeller University
Computer-Aided Diagnosis for Spitzoid Lesions Classification Using Artificial Intelligence Techniques
Spitzoid lesions may be largely categorized into Spitz Nevus, Atypical Spitz Tumors, and Spitz Melanomas. Classifying a lesion precisely as Atypical Spitz Tumors or AST is challenging and often requires the integration of...
Published by: IGI Global Scientific Publishing
Chronic Migraine: Role of CGRP antagonists and Botox
Gabriella Hassan
Jan 01, 0001
Chronic migraine (CM) is characterized by the International Headache Society classification (ICHD-3) as headache that occurs for greater than or equal to 15 days a month, lasting 4 or more hours. For chronic migraine patients...
Chronic migraine Medication CGRP CGRP-antagonists OnabotulinumtoxinA Analytical, Diagnostic and Therapeutic Techniques and Equipment Chemicals and Drugs health information technology
Published by: Harrisburg University of Science and Technology
Myocardial Fibrosis in Heart Failure
All heart muscle diseases that cause chronic heart failure finally converge into one dreaded pathological process that is myocardial fibrosis. Myocardial fibrosis predicts major adverse cardiovascular events and death, yet we...
Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins.
Over the past decade, there has been a growing interest in investigating whether disordered proteins can be targeted for clinical purposes using small molecules [1-8]. While small-molecule binding to disordered proteins can be...
Determination of Thermal Niche for a Ground Beetle Predator (Bembidion spp.) in Barley Fields
Gabriella R Altmire
Jan 01, 0001
The activity density of Bembidion spp. was studied in barley fields in relation to temperature to determine its thermal optimum and thermal niche breadth, and to evaluate whether its thermal niche is complementary or redundant...
Published by: Ursinus College
Effect of Plant Biodiversity on Insect Pests in a Forage Agroecosystem
Gabriella R Altmire
Jan 01, 0001
Agroecosystems are species-poor in comparison to natural ecosystems and this may lead to an increased susceptibility to pest outbreaks. Pesticides prevent pest outbreaks; however, they threaten human, non-human, and...
agriculture Biodiversity insect herbivore plant monoculture agriculture Biology Ecology and Evolutionary Biology entomology Life Sciences
Published by: Ursinus College
Inclusive Education and UDL Professional Development for Teachers in Sweden and India
In education, the factors involved in a successful inclusive education classroom are diverse and multidimensional, with a growing research base. Universal design for learning (UDL) can help educators address the varied needs of...
Gender & Diversity Education Curriculum Development and Instructional Design Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
Identity Determinants of the Translocation Signal for a Type 1 Secretion System
The toxin hemolysin A was first identified in uropathogenic E. coli strains and shown to be secreted in a one-step mechanism by a dedicated secretion machinery. This machinery, which belongs to...
Olivia Spitz, Isabelle N Erenburg, Kerstin Kanonenberg, Sandra Peherstorfer, Michael HH Lenders, Jens Reiners, Miao Ma, Ben F Luisi, Sander HJ Smits, Lutz Schmitt
Feb 24, 2022
Signalling adjustments to direct and indirect environmental effects on signal perception in meerkats.
The efficiency of communication between animals is determined by the perception range of signals. With changes in the environment, signal transmission between a sender and a receiver can be influenced both directly, where the...
Myocardial Fibrosis in Heart Failure
Abstract: All heart muscle diseases that cause chronic heart failure finally converge into one dreaded pathological process that is myocardial fibrosis. Myocardial fibrosis predicts major adverse cardiovascular events and death...
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer's Aβ Peptide.
The stabilization of native states of proteins is a powerful drug discovery strategy. It is still unclear, however, whether this approach can be applied to intrinsically disordered proteins. Here, we report a small molecule that...
Stalagmite evidence of Last Glacial Maximum to early Holocene climate variability in southwestern Iran
Mojgan Soleimani, Alireza Nadimi, Gabriella Koltai, Yuri Dublyansky, Stacy Carolin, Christoph Spotl
Oct 29, 2022
Glacial periods and their terminations are useful for assessing the full scale of natural climate variability in the diverse climate regions of West Asia (i.e. deserts, mountains, alluvial plains, coastal zones). In this study...
Financial Stress Interacts With CLOCK Gene to Affect Migraine.
Daniel Baksa, Xenia Gonda, Nora Eszlari, Peter Petschner, Veronika Acs, Lajos Kalmar, JF William Deakin, Gyorgy Bagdy, Gabriella Juhasz
Feb 17, 2020
Previous studies suggested that both maladaptive stress response and circadian dysregulation might have a role in the background of migraine. However, effects of circadian genes on migraine have not been tested yet. In the...
The Grizzly, February 11, 1991
Krishni Patrick, Megan Mendte, Mark Hallinger, Kristen Schwarz, Naimish Pandya, Todd Koser, Gabriele Scheel, Christopher Phiel, Steven Grubb, Laura Zobel, Tonya Ugoretz, Trey Gelston, Judd Woytek, Amy Flemming, Ellen Shatz, Sara Jacobson, Chris Major, Richard P. Richter, Eleanore Hajian, Adria Harris, Beverly Oehlert, Terri Johnson
Jan 01, 0001
Fraternity Pledging Returns Again Wachtel Explains the Poverty of Affluence The Changing War Peer Educators and Community Service Alumni Visit the Ballet Study Abroad Memorable A Valentine History Side Winders Dance...
Ursinus College Collegeville Pennsylvania newspaper Gulf War William Rosenthal gymnastics wrestling track team Basketball Swimming Valentine's Day campus security study abroad Kappa Delta Kappa Young Alumni peer education pledging fraternities Paul Wachtel cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle.
John A Halsall, Simon Andrews, Felix Krueger, Charlotte E Rutledge, Gabriella Ficz, Wolf Reik, Bryan M Turner
Apr 12, 2021
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved...
Has Academic Freedom Failed? Can Liberalism Defend Academic Freedom?
Daniel Becker
Jan 01, 0001
Academic freedom has been a keystone of American higher education for over 100 years. It is the freedom of academics to instruct and research, free from interference by both their institutions, and the government. It is often...
Liberalism academic freedom Higher Education John Stuart Mill Patrick Deneen Arts and Humanities Philosophy
Published by: Ursinus College
Tumor Necrosis Factor α Influences Phenotypic Plasticity and Promotes Epigenetic Changes in Human Basal Forebrain Cholinergic Neuroblasts.
Giulia Guarnieri, Erica Sarchielli, Paolo Comeglio, Erika Herrera-Puerta, Irene Piaceri, Benedetta Nacmias, Matteo Benelli, Gavin Kelsey, Mario Maggi, Pasquale Gallina, Gabriella Barbara Vannelli, Annamaria Morelli
Nov 09, 2020
TNFα is the main proinflammatory cytokine implicated in the pathogenesis of neurodegenerative disorders, but it also modulates physiological functions in both the developing and adult brain. In this study, we investigated a...
Alzheimer’s disease DNA Methylation NGF TNFα receptors ciliogenesis human fetal neurons Neurogenesis Neuroinflammation Nucleus basalis of Meynert Basal Forebrain basal nucleus of Meynert Cell Line Cholinergic Neurons DNA Methylation Epigenesis Genetic Humans Microtubule-Associated Proteins Nerve Tissue Proteins Neuronal Plasticity Receptors Nerve Growth Factor Receptors Tumor Necrosis Factor Type II Tumor Necrosis Factor-alpha whole genome sequencing
Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages
Milos Gojkovic, Pedro P Cunha, Gabriella S Darmasaputra, Laura Barbieri, Helene Rundqvist, Pedro Veliça, Randall S Johnson
Jun 10, 2021
Myeloid cell interactions with cells of the adaptive immune system are an essential aspect of immunity. A key aspect of that interrelationship is its modulation by the microenvironment. Oxygen is known to influence...
HIF Nitric oxide prolyl hydroxylase inhibitors Hypoxia immunosuppression Myeloid Cells von Hippel-Lindau. Adaptive Immunity Animals CD8-Positive T-Lymphocytes Cell Hypoxia Cell Line Tumor Cell Proliferation Coculture Techniques Glycine Humans Hypoxia-Inducible Factor 1 alpha Subunit Isoquinolines MACROPHAGES Mice Mice Transgenic Oxygen Von Hippel-Lindau Tumor Suppressor Protein
Cross-assignment discrimination in pay
The traditional Becker/Arrow style model of discrimination depicts majority and minority workers as perfectly substitutable inputs, implying that all workers have the same job assignment. The model is only appropriate for...
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