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Results: 783
Placentation and antitumor immunity regulated by a scaffolding protein in NK cells.
Francesco Colucci
Jul 24, 2019
Natural killer cells use the Gab3 adaptor protein to limit trophoblast invasion during pregnancy and to reject tumor cells. See the related Research Article by Sliz et al.
Sharing Knowledge With Young and Established Students of Immunology by the Neapolitan Gulf at the Ruggero Ceppellini Advanced School.
Francesco Colucci
Jan 20, 2020
In his Origin, Charles Darwin led the foundations to debunk the long-held belief that man and animals derive from separate lineages, landing the final blow in The Descent of Man. The discovery in the mid-1980’s that fertilized...
Review of Francesco Pelosi's Plato on Music, Soul and Body (trans. Sophie Henderson)
Mark Walley
Jan 06, 2012
Review of Francesco Pelosi's Plato on Music, Soul and Body (trans. Sophie Henderson)
Published by: Memorial University of Newfoundland
Review of Francesco Pelosi's Plato on Music, Soul and Body (trans. Sophie Henderson)
Mark Walley
Jan 06, 2012
Review of Francesco Pelosi's Plato on Music, Soul and Body (trans. Sophie Henderson)
Published by: Memorial University of Newfoundland
Microbes, immunity and cancer in Capri
Not many but much – ‘Non multa sed multum’ – is the motto chosen in 1991 by Serafino Zappacosta and the other founders of the EFIS‐EJI Advanced School of Immunology Ruggero Ceppellini. The motto was pertinent to the 29th Course...
Maternal natural killer cells at the intersection between reproduction and mucosal immunity
Abstract: Many maternal immune cells populate the decidua, which is the mucosal lining of the uterus transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages help the uterine vasculature adapt to...
NKG2A Immune Checkpoint in Vδ2 T Cells
Valentina Cazzetta, Delphine Depierreux, Francesco Colucci, Joanna Mikulak, Domenico Mavilio
Mar 28, 2023
Immune regulation has revolutionized cancer treatment with the introduction of T-cell-targeted immune checkpoint inhibitors (ICIs). This successful immunotherapy has led to a more complete view of cancer that now considers not...
NKG2A inhibitory receptors cancer immunotherapy γδ T cells Therapeutic monoclonal antibodies Immune Checkpoint Inhibitors
Published by: Cancers
IL-12/15/18-preactivated NK cells suppress GvHD in a mouse model of mismatched hematopoietic cell transplantation.
Cytokine-induced NK cells GvHD HSCT Lymphoma Animals Cytokines Disease Models Animal Female Gene Expression Graft vs Host Disease Hematopoietic Stem Cell Transplantation Immunotherapy Adoptive Interferon-gamma Interleukin-12 Interleukin-15 Interleukin-18 Killer Cells Natural Lymphocyte Activation Mice Phenotype T-Box Domain Proteins Transplantation Chimera Transplantation Homologous
Biology and pathology of the uterine microenvironment and its natural killer cells.
Tissues are the new frontier of discoveries in immunology. Cells of the immune system are an integral part of tissue physiology and immunity. Determining how immune cells inhabit, housekeep, and defend gut, lung, brain, liver...
How Do Uterine Natural Killer and Innate Lymphoid Cells Contribute to Successful Pregnancy?
Oisín Huhn, Xiaohui Zhao, Laura Esposito, Ashley Moffett, Francesco Colucci, Andrew M. Sharkey
Jul 07, 2021
Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both before and during pregnancy. Circumstantial evidence suggests they play important roles in regulating placental development but exactly...
How Do Uterine Natural Killer and Innate Lymphoid Cells Contribute to Successful Pregnancy?
Oisín Huhn, Xiaohui Zhao, Laura Esposito, Ashley Moffett, Francesco Colucci, Andrew M Sharkey
Jul 30, 2021
Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both before and during pregnancy. Circumstantial evidence suggests they play important roles in regulating placental development but exactly...
Biology and pathology of the uterine microenvironment and its natural killer cells
Abstract: Tissues are the new frontier of discoveries in immunology. Cells of the immune system are an integral part of tissue physiology and immunity. Determining how immune cells inhabit, housekeep, and defend gut, lung...
Beyond Maternal Tolerance
Delphine M Depierreux, Jens Kieckbusch, Norman Shreeve, Delia A Hawkes, Bryan Marsh, Robert Blelloch, Andrew Sharkey, Francesco Colucci
May 24, 2022
Reproductive immunology has moved on from the classical Medawar question of 60 years ago "why doesn't the mother reject the fetus?". Looking beyond fetal-maternal tolerance, modern reproductive immunology focuses on how the...
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