Search
Results: 389
Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.
Sara Ruiz-Pinto, Guillermo Pita, Miguel Martín, Teresa Alonso-Gordoa, Daniel R Barnes, María R Alonso, Belén Herraez, Purificación García-Miguel, Javier Alonso, Antonio Pérez-Martínez, Antonio J Cartón, Federico Gutiérrez-Larraya, José A García-Sáenz, Javier Benítez, Douglas F Easton, Ana Patiño-García, Anna González-Neira
Jan 30, 2018
PURPOSE: Anthracyclines are widely used chemotherapeutic drugs that can cause progressive and irreversible cardiac damage and fatal heart failure. Several genetic variants associated with anthracycline-induced cardiotoxicity...
Anthracyclines Chronic cardiotoxicity ETFB Long-term cancer survivors Low-frequency variants Adult Aged Anthracyclines Breast Neoplasms Cancer Survivors Cardiotoxicity Electron-Transferring Flavoproteins Exome Female Gene Expression Regulation Neoplastic Genetic Association Studies Genetic Predisposition to Disease Heart Failure Humans Middle Aged Mitochondria
Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
Sara Ruiz-Pinto, Guillermo Pita, Ana Patiño-García, Javier Alonso, Antonio Pérez-Martínez, Antonio J Cartón, Federico Gutiérrez-Larraya, María R Alonso, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Carmen Gómez-Santos, Deborah J Thompson, Douglas F Easton, Javier Benítez, Anna González-Neira
Apr 06, 2018
Ante rem structuralism and the semantics of instantial terms
Sofía Meléndez Gutiérrez
Oct 24, 2022
Abstract: Ante rem structures were posited as the subject matter of mathematics in order to resolve a problem of referential indeterminacy within mathematical discourse. Nevertheless, ante rem structuralists are inevitably...
Original Research Mathematical structuralism Ante rem structuralism Referential indeterminacy Instantial terms Instantial reasoning
Published by: Springer Netherlands
Ante rem structuralism and the semantics of instantial terms
Abstract Ante rem structures were posited as the subject matter of mathematics in order to resolve a problem of referential indeterminacy within mathematical discourse....
Sofía Meléndez Gutiérrez
Oct 10, 2022
A gene catalogue of the amphioxus nervous system.
Elia Benito-Gutiérrez
Sep 05, 2018
The elaboration of extremely complex nervous systems is a major success of evolution. However, at the dawn of the post-genomic era, few data have helped yet to unravel how a nervous system develops and evolves to complexity. On...
Should different countries participating in PISA interpret socioeconomic background in the same way? A measurement invariance approach
It has been claimed that there is a lack of theory-driven constructs and a lack of cross-country comparability in International Large-Scale Assessment (ILSA)’s socio-economic background scales. To address these issues, a new...
Restricted Proliferation During Neurogenesis Contributes to Regionalisation of the Amphioxus Nervous System.
The central nervous system of the cephalochordate amphioxus consists of a dorsal neural tube with an anterior brain. Two decades of gene expression analyses in developing amphioxus embryos have shown that, despite apparent...
Methods for generating year-round access to amphioxus in the laboratory.
Cephalochordates, commonly known as amphioxus, are key to understanding vertebrate origins. However, laboratory work suffers from limited access to adults and embryonic material. Here we report the design and experimental...
Should different countries participating in PISA interpret socioeconomic background in the same way? A measurement invariance approach
It has been claimed that there is a lack of theory-driven constructs and a lack of cross-country comparability in International Large-Scale Assessment (ILSA)’s socio-economic background scales. To address these issues, a new...
Electronic Origin of α″ to β Phase Transformation in Ti-Nb-Based Thin Films upon Hf Microalloying.
José Julio Gutiérrez Moreno, Nikolaos T Panagiotopoulos, Georgios A Evangelakis, Christina E Lekka
Mar 15, 2020
We present results on thin Ti-Nb-based films containing Hf at various concentrations grown by magnetron sputtering. The films exhibit α" patterns at Hf concentrations up to 11 at.%, while at 16 at.% Hf, the β-phase emerges as a...
Optical Fiber Sensors
Mohamed Elsherif, Ahmed E Salih, Monserrat Gutiérrez Muñoz, Fahad Alam, Bader AlQattan, Dennyson Savariraj Antonysamy, Mohamed Fawzi Zaki, Ali K Yetisen, Seongjun Park, Timothy D Wilkinson, Haider Butt
Jul 14, 2022
Fiber‐optic technology emerged originally for applications in data transmission and telecommunications. However, sensors based on fiber‐optics have been developed rapidly because of their excellent sensing performances and...
Location, number and factors associated with cerebral microbleeds in an Italian-British cohort of CADASIL patients.
Serena Nannucci, Valentina Rinnoci, Giovanni Pracucci, Andrew D MacKinnon, Francesca Pescini, Poneh Adib-Samii, Silvia Bianchi, Maria Teresa Dotti, Antonio Federico, Domenico Inzitari, Hugh S Markus, Leonardo Pantoni
Apr 12, 2018
BACKGROUND AND PURPOSE: The frequency, clinical correlates, and risk factors of cerebral microbleeds (CMB) in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) are still poorly...
A regularised Dean-Kawasaki model
The Dean–Kawasaki model consists of a nonlinear stochastic partial differential equation featuring a conservative, multiplicative, stochastic term with non-Lipschitz coefficient, driven by space-time white noise; this...
Impact Pathways
Purpose: International Journal of Operations and Production Management (IJOPM)'s Impact Pathway (IP) section has been launched in 2020 to host short contributions grounded in current managerial practices and/or policy...
Impact Pathways
Purpose: International Journal of Operations and Production Management (IJOPM)'s Impact Pathway (IP) section has been launched in 2020 to host short contributions grounded in current managerial practices and/or policy...
From weakly interacting particles to a regularised Dean–Kawasaki model
The evolution of finitely many particles obeying Langevin dynamics is described by Dean-Kawasaki equations, a class of stochastic equations featuring a non-Lipschitz multiplicative noise in divergence form. We derive a...
Teaching Accompaniment
Steve Reifenberg
Jan 01, 2023
Engaging in a complicated world to bring about positive change is challenging. Students often view themselves as either optimistic changemakers helping the “needy” or, conversely, recognize their own privilege and complicity in...
Published by: IGI Global Scientific Publishing
Relativistic quasiparticle self-consistent electronic structure of hybrid halide perovskite photovoltaic absorbers
Solar cells based on a light absorbing layer of the organometal halide perovskite CH3NH3PbI3 have recently surpassed 15% conversion efficiency, though how these materials work remains largely unknown. We analyze the...
The effect of NOTCH3 pathogenic variant position on CADASIL disease severity
Julie W Rutten, Bastian J Van Eijsden, Marco Duering, Eric Jouvent, Christian Opherk, Leonardo Pantoni, Antonio Federico, Martin Dichgans, Hugh S Markus, Hugues Chabriat, Saskia AJ Lesnik Oberstein
Nov 06, 2018
PURPOSE: CADASIL is a small-vessel disease caused by a cysteine-altering pathogenic variant in one of the 34 epidermal growth factor-like repeat (EGFr) domains of the NOTCH3 protein. We recently found that pathogenic variant in...
|
|< |
< |
1 |