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Little evidence for Fast Mapping (FM) in adults
Conventional memory theory proposes that the hippocampus is initially responsible for encoding new information, before this responsibility is gradually transferred to the neocortex. Therefore, a report in 2011 by Sharon et al....
Modelling of the cancer cell cycle as a tool for rational drug development
The dynamic of cancer is intimately linked to a dysregulation of the cell cycle and signalling pathways. It has been argued that selectivity of treatments could exploit loss of checkpoint function in cancer cells, a concept...
Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells.
Y Lin, FM Richards, B-F Krippendorff, JL Bramhall, JA Harrington, TE Bapiro, A Robertson, D Zheleva, DI Jodrell
Feb 12, 2020
BACKGROUND: Amplification of aurora kinase A (AK-A) overrides the mitotic spindle assembly checkpoint, inducing resistance to taxanes. RNA interference targeting AK-A in human pancreatic cancer cell lines enhanced taxane...
Investigating Fast Mapping Task Components
Fast mapping (FM) is an incidental learning process that is hypothesized to allow rapid, cortical-based memory formation, independent of the normal, hippocampally dependent episodic memory system. It is believed to underlie the...
A Study of the Transmission of Sensory Information in the Cat Spinal Cord
Paul Richards Burgess
Jan 01, 0001
With the hope of elucidating neurophysiological mechanisms involved in cutaneous modality discrimination, a comparison was made between activity recorded from single fibers in the dorsal columns and lateral funiculus of the cat...
Published by: Rockefeller University
Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.
TE Bapiro, KK Frese, A Courtin, JL Bramhall, B Madhu, N Cook, A Neesse, JR Griffiths, DA Tuveson, DI Jodrell, FM Richards
Nov 16, 2017
BACKGROUND: The modest benefits of gemcitabine (dFdC) therapy in patients with pancreatic ductal adenocarcinoma (PDAC) are well documented, with drug delivery and metabolic lability cited as important contributing factors. We...
Impact of Early Infant Growth, Duration of Breastfeeding and Maternal Factors on Total Body Fat Mass and Visceral Fat at 3 and 6 Months of Age.
Laura M Breij, Marieke Abrahamse-Berkeveld, Dennis Acton, Emanuella De Lucia Rolfe, Ken K Ong, Anita CS Hokken-Koelega
Apr 13, 2018
BACKGROUND: Accelerated gain in fat mass in the first months of life is considered to be a risk factor for adult diseases, given the tracking of infancy fat mass into adulthood. Our objective was to assess the influence of early...
Longitudinal fat mass and visceral fat during the first 6 months after birth in healthy infants
Laura M Breij, Gerthe F Kerkhof, Emanuella De Lucia Rolfe, Ken K Ong, Marieke Abrahamse-Berkeveld, Dennis Acton, Anita CS Hokken-Koelega
Jan 17, 2020
INTRODUCTION: Body composition in early life influences the development of obesity during childhood and beyond. It is, therefore, important to adequately determine longitudinal body composition during the first months of life....
Neurochemical Correlates of Brain Atrophy in Fibromyalgia Syndrome
Paola Feraco, Salvatore Nigro, Luca Passamonti, Alessandro Grecucci, Maria Eugenia Caligiuri, Cesare Gagliardo, Antonella Bacci
Jun 21, 2020
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated...
Response to commentaries on our review of Fast Mapping in adults.
We thank all the commentators for their thoughts on our review of Fast Mapping (FM) in adults, where we questioned the evidence that FM is a distinct learning mechanism, and urged caution over the excitement generated by the...
Maintenance Resources Optimization Using Pareto Analysis
Managing resource allocation for optimum effectiveness at various levels of maintenance activities is always a challenging task. Optimizing maintenance resources enables an organization to set priorities towards achieving...
Published by: IGI Global Scientific Publishing
The bound coherent neutron scattering lengths of the oxygen isotopes
Henry E Fischer, J Mike Simonson, Jörg C Neuefeind, Hartmut Lemmel, Helmut Rauch, Anita Zeidler, Philip S Salmon
Dec 19, 2012
The technique of neutron interferometry was used to measure the bound coherent neutron scattering length b(coh) of the oxygen isotopes (17)O and (18)O. From the measured difference in optical path between two water samples...
Neurochemical Correlates of Brain Atrophy in Fibromyalgia Syndrome
Paola Feraco, Salvatore Nigro, Luca Passamonti, Alessandro Grecucci, Maria Eugenia Caligiuri, Cesare Gagliardo, Antonella Bacci
Sep 09, 2020
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated...
Discrimination of the phase of amplitude modulation applied to different carriers
The discrimination of amplitude modulation (AM) from frequency modulation (FM) of a 1000-Hz carrier, with equally detectable AM and FM, is better for a 2-Hz than for a 10-Hz modulation rate. This might reflect greater...
The bound coherent neutron scattering lengths of the oxygen isotopes
Henry E Fischer, J Mike Simonson, Jörg C Neuefeind, Hartmut Lemmel, Helmut Rauch, Anita Zeidler, Philip S Salmon
Dec 19, 2012
The technique of neutron interferometry was used to measure the bound coherent neutron scattering length b(coh) of the oxygen isotopes (17)O and (18)O. From the measured difference in optical path between two water samples...
Dual Coding of Frequency Modulation in the Ventral Cochlear Nucleus.
Frequency modulation (FM) is a common acoustic feature of natural sounds and is known to play a role in robust sound source recognition. Auditory neurons show precise stimulus-synchronized discharge patterns that may be used for...
Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer.
E Hessmann, MS Patzak, L Klein, N Chen, V Kari, I Ramu, TE Bapiro, KK Frese, A Gopinathan, FM Richards, DI Jodrell, C Verbeke, X Li, R Heuchel, JM Löhr, SA Johnsen, TM Gress, V Ellenrieder, A Neesse
Feb 15, 2017
Chemotherapy DRUG METABOLISM pancreatic cancer PANCREATIC FIBROSIS 5'-Nucleotidase Actins Animals Antimetabolites Antineoplastic Carcinoma Pancreatic Ductal Cell Line Tumor Cytidine Triphosphate Deoxycytidine FIBROBLASTS Floxuridine Humans Liver Liver Neoplasms Mice Pancreatic Neoplasms Primary Cell Culture Tumor Microenvironment Gemcitabine
Stunting in infancy, pubertal trajectories and adult body composition
Glory Chidumwa, Rihlat Said-Mohamed, Lukhanyo H Nyati, Feziwe Mpondo, Tinashe Chikowore, Alessandra Prioreschi, Juliana Kagura, Lisa J Ware, Lisa K Micklesfield, Shane A Norris
Aug 14, 2021
BACKGROUND/OBJECTIVES: Childhood rapid growth and earlier puberty onset have been associated with adult obesity. However, the association between childhood stunting, pubertal timing and adult obesity is unclear. We examined...
The Ursinus Weekly, December 15, 1913
Lary Baker Small
Jan 01, 0001
Schaff Society gives Richard III Captain Hobson predicts national prohibition Freshmen class holds banquet Women's Bible class Classical group will have Dr. Richards here Historical-Political discusses labor organizations ...
Ursinus College Collegeville Pennsylvania newspaper Richmond Hobson Schaff literary society YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Stunting in infancy, pubertal trajectories and adult body composition
Glory Chidumwa, Rihlat Said-Mohamed, Lukhanyo H. Nyati, Feziwe Mpondo, Tinashe Chikowore, Alessandra Prioreschi, Juliana Kagura, Lisa J. Ware, Lisa K. Micklesfield, Shane A. Norris
Feb 09, 2021
Abstract: Background/objectives: Childhood rapid growth and earlier puberty onset have been associated with adult obesity. However, the association between childhood stunting, pubertal timing and adult obesity is unclear. We...
Ebola
Review of: Ebola: how a people's science helped end an epidemic , by Richards Paul. London: Zed Books, 2016. xii + 180 pp. £20.00 (paperback). ISBN 978 1 78360 858 4
Statistical critical reactive maintenance characterisation for digital twin implementation in universities
Purpose: Facilities management (FM) plays a key role in the performance of businesses to ensure the comfort of users and the sustainable use of natural resources over operation and maintenance. Nevertheless, reactive...
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