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The Role of Activation-Induced Cytidine Deaminase in Antibody Diversification and B Cell Malignancies
Eleonora Market
Jan 01, 0001
Activation-induced cytidine deaminase (AID) is indispensable for somatic hypermutation (SHM) and class switch recombination (CSR) in B cells. SHM alters the affinity of an antibody for its corresponding antigen by introducing...
Published by: Rockefeller University
Does Patient Health Behaviour respond to Doctor Effort?
Incentive pay systems have been introduced in public sectors such as education and health care. In these sectors the output (education or health respectively) depends on the actions of different agents and it is unclear what the...
Can payers use prices to improve quality? Evidence from English hospitals
In most activity-based financing systems, payers set prices reactively based on historical averages of hospital reported costs. If hospitals respond to prices, payers might set prices proactively to affect the volume of...
Autonomous self-healing structural composites with bio-inspired design
Strong and tough natural composites such as bone, silk or nacre are often built from stiff blocks bound together using thin interfacial soft layers that can also provide sacrificial bonds for self-repair. Here we show that it is...
The effect of cash transfers on mental health – New evidence from South Africa

BACKGROUND: Mental health and poverty are strongly interlinked. There is a gap in the literature on the effects of poverty alleviation programmes on mental health. We aim to fill this gap by studying the effect of an...

Can payers use prices to improve quality? Evidence from English hospitals
In most activity-based financing systems, payers set prices reactively based on historical averages of hospital reported costs. If hospitals respond to prices, payers might set prices proactively to affect the volume of...
Estimating the late-life effects of social and emotional skills in childhood using mid-life mediators
Social and emotional skills are known to affect health and non-health outcomes, but there is limited evidence on whether these skills in childhood affect late life outcomes because of a shortage of long-running datasets...
Protecting Adolescents in Low- And Middle-Income Countries from Interpersonal Violence (PRO YOUTH TRIAL)

Background: Interpersonal violence can significantly reduce adolescents' opportunities for becoming happy and healthy adults. Central America is the most violent region in the world and it is estimated that adolescents are...

Joint analysis of gravitational-wave and electromagnetic data of mergers

On 2017 August 17, Advanced LIGO and Virgo observed GW170817, the first gravitational-wave (GW) signal from a binary neutron star merger. It was followed by a short-duration gamma-ray burst, GRB 170817A, and by a non-thermal...

The effect of cash transfers on mental health – New evidence from South Africa

BACKGROUND: Mental health and poverty are strongly interlinked. There is a gap in the literature on the effects of poverty alleviation programmes on mental health. We aim to fill this gap by studying the effect of an...

Does Patient Health Behaviour respond to Doctor Effort?
Incentive pay systems have been introduced in public sectors such as education and health care. In these sectors the output (education or health respectively) depends on the actions of different agents and it is unclear what the...
The effects in-utero exposure to influenza on mental health and mortality risk throughout the life-course.
Studies examining the later-life health consequences of in-utero exposure to influenza have typically estimated effects on physical health conditions, with little evidence of effects on mental health outcomes or mortality....
Protecting Adolescents in Low- And Middle-Income Countries from Interpersonal Violence (PRO YOUTH TRIAL)

Background: Interpersonal violence can significantly reduce adolescents' opportunities for becoming happy and healthy adults. Central America is the most violent region in the world and it is estimated that adolescents are...

Estimating the late-life effects of social and emotional skills in childhood using mid-life mediators
Social and emotional skills are known to affect health and non-health outcomes, but there is limited evidence on whether these skills in childhood affect late life outcomes because of a shortage of long-running datasets...
The effects in-utero exposure to influenza on mental health and mortality risk throughout the life-course.
Studies examining the later-life health consequences of in-utero exposure to influenza have typically estimated effects on physical health conditions, with little evidence of effects on mental health outcomes or mortality....
Joint analysis of gravitational-wave and electromagnetic data of mergers

On 2017 August 17, Advanced LIGO and Virgo observed GW170817, the first gravitational-wave (GW) signal from a binary neutron star merger. It was followed by a short-duration gamma-ray burst, GRB 170817A, and by a non-thermal...

Nonalcoholic Fatty Liver Disease in Children.
Nonalcoholic steatohepatitis, a progressive form of nonalcoholic fatty liver disease (NAFLD), is one of the most common hepatic diseases in children who present with particular risk factors including obesity, sedentary...
Inkjet Printing Infiltration of the Doped Ceria Interlayer in Commercial Anode-Supported SOFCs.
Single-step inkjet printing infiltration with doped ceria Ce0.9Ye0.1O1.95 (YDC) and cobalt oxide (CoxOy) precursor inks was performed in order to modify the properties of the doped ceria interlayer in commercial (50 × 50 × 0.5...

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