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Results: 32
Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland.
Aimun AB Jamjoom, Alexis J Joannides, Michael Tin-Chung Poon, Aswin Chari, Malik Zaben, Mutwakil AH Abdulla, Joy Roach, Laurence J Glancz, Anna Solth, John Duddy, Paul M Brennan, Roger Bayston, Diederik O Bulters, Conor L Mallucci, Michael D Jenkinson, William P Gray, Jothy Kandasamy, Peter J Hutchinson, Angelos G Kolias, Aminul I Ahmed, British Neurosurgical Trainee Research Collaborative
Jan 22, 2018
OBJECTIVES: External ventricular drain (EVD) insertion is a common neurosurgical procedure. EVD-related infection (ERI) is a major complication that can lead to morbidity and mortality. In this study, we aimed to establish a...
Adolescent Adult Aged Aged 80 and over Catheter-Related Infections Catheters Indwelling Cerebral Ventricles Child Child Preschool Female Humans Infant Infant Newborn Ireland Male Middle Aged Neurosurgical Procedures Postoperative Complications Proportional Hazards Models Prospective Studies Staphylococcal Infections United Kingdom Ventriculostomy Young Adult
An Intraoperative Visualization System Using Hyperspectral Imaging to Aid in Brain Tumor Delineation.
Himar Fabelo, Samuel Ortega, Raquel Lazcano, Daniel Madroñal, Gustavo M Callicó, Eduardo Juárez, Rubén Salvador, Diederik Bulters, Harry Bulstrode, Adam Szolna, Juan F Piñeiro, Coralia Sosa, Aruma J O'Shanahan, Sara Bisshopp, María Hernández, Jesús Morera, Daniele Ravi, B Ravi Kiran, Aurelio Vega, Abelardo Báez-Quevedo, Guang-Zhong Yang, Bogdan Stanciulescu, Roberto Sarmiento
Apr 12, 2019
Hyperspectral imaging (HSI) allows for the acquisition of large numbers of spectral bands throughout the electromagnetic spectrum (within and beyond the visual range) with respect to the surface of scenes captured by sensors....
Pharmacological management of post-traumatic seizures in adults
Harry Mee, Angelos G Kolias, Aswin Chari, Ari Ercole, Fiona Lecky, Carole Turner, Catrin Tudur-Smith, Jonathan Coles, Fahim Anwar, Antonio Belli, Mark Manford, Timothy Ham, Catherine McMahon, Diederik Bulters, Chris Uff, John S Duncan, Mark H Wilson, Anthony G Marson, Peter J Hutchinson
Nov 15, 2018
BACKGROUND: Patient selection for seizure prophylaxis after traumatic brain injury (TBI) and duration of anti-epileptic drug treatment for patients with early post-traumatic seizures (PTS), remain plagued with uncertainty. In...
Exceptional scalar theories in de Sitter space
The special galileon and Dirac-Born-Infeld (DBI) theories are effective field theories of a single scalar field that have many interesting properties in flat space. These theories can be extended to all maximally symmetric...
Regular Article - Theoretical Physics Effective Field Theories global symmetries Space-Time Symmetries
Published by: Springer Berlin Heidelberg
Spatio-spectral classification of hyperspectral images for brain cancer detection during surgical operations.
Himar Fabelo, Samuel Ortega, Daniele Ravi, B Ravi Kiran, Coralia Sosa, Diederik Bulters, Gustavo M Callicó, Harry Bulstrode, Adam Szolna, Juan F Piñeiro, Silvester Kabwama, Daniel Madroñal, Raquel Lazcano, Aruma J-O'Shanahan, Sara Bisshopp, María Hernández, Abelardo Báez, Guang-Zhong Yang, Bogdan Stanciulescu, Rubén Salvador, Eduardo Juárez, Roberto Sarmiento
Apr 12, 2019
Surgery for brain cancer is a major problem in neurosurgery. The diffuse infiltration into the surrounding normal brain by these tumors makes their accurate identification by the naked eye difficult. Since surgery is the common...
Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension.
Peter J Hutchinson, Angelos G Kolias, Ivan S Timofeev, Elizabeth A Corteen, Marek Czosnyka, Jake Timothy, Ian Anderson, Diederik O Bulters, Antonio Belli, C Andrew Eynon, John Wadley, A David Mendelow, Patrick M Mitchell, Mark H Wilson, Giles Critchley, Juan Sahuquillo, Andreas Unterberg, Franco Servadei, Graham M Teasdale, John D Pickard, David K Menon, Gordon D Murray, Peter J Kirkpatrick, RESCUEicp Trial Collaborators
Sep 21, 2016
Risk of Aneurysm Rupture (ROAR) study
Samuel Hall, Jacqueline Birks, Ian Anderson, Andrew Bacon, Paul M Brennan, David Bennett, Emmanuel Chavredakis, Giles Critchley, Graham Dow, Jonathan Downer, James Galea, Patrick Grover, Nihal Gurusinghe, Adel Helmy, Gueorgui Kounin, Nitin Mukerji, Hiren Patel, Jash Patel, Nicholas Ross, Jerome St George, Mario Teo, Christos Michael Tolias, Nikolaos Tzerakis, Christopher Uff, Janneke van Beijum, Kristin Veighey, Edward White, Peter Whitfield, Diederik Oliver Bulters
Apr 17, 2023
Introduction
Unruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target...
stroke EPIDEMIOLOGY Neurosurgery Humans Intracranial Aneurysm Subarachnoid Hemorrhage Aneurysm Ruptured Risk Factors Adult Multicenter Studies as Topic United Kingdom
Published by: BMJ Open
UV constraints on massive spinning particles
Abstract: Self-interacting massive particles with spin ≥ 1 unavoidably violate unitarity; the question is at what scale. For spin-1 the strong coupling scale (at which perturbative unitarity is lost) cannot be raised by any...
UV constraints on massive spinning particles
Abstract: Self-interacting massive particles with spin ≥ 1 unavoidably violate unitarity; the question is at what scale. For spin-1 the strong coupling scale (at which perturbative unitarity is lost) cannot be raised by any...
Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial
Angelos G Kolias, Ellie Edlmann, Eric P Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, Peter J Hutchinson, British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators
Jun 20, 2019
After publication of the original article [1], the authors notified that that one of the BNTRC institutional collaborator names was misspelled.
Risk of Aneurysm Rupture (ROAR) study
Samuel Hall, Jacqueline Birks, Ian Anderson, Andrew Bacon, Paul M Brennan, David Bennett, Emmanuel Chavredakis, Giles Critchley, Graham Dow, Jonathan Downer, James Galea, Patrick Grover, Nihal Gurusinghe, Adel Helmy, Gueorgui Kounin, Nitin Mukerji, Hiren Patel, Jash Patel, Nicholas Ross, Jerome St George, Mario Teo, Christos Michael Tolias, Nikolaos Tzerakis, Christopher Uff, Janneke van Beijum, Kristin Veighey, Edward White, Peter Whitfield, Diederik Oliver Bulters, ROAR Investigators
Mar 22, 2023
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial
Angelos G Kolias, Ellie Edlmann, Eric P Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, Peter J Hutchinson, British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators
Feb 07, 2019
BACKGROUND: Chronic subdural haematoma (CSDH) is a common neurosurgical condition, typically treated with surgical drainage of the haematoma. However, surgery is associated with mortality and morbidity, including up to 20%...
chronic subdural haematoma Dexamethasone Neurology Neurosurgery Randomised control trial Cost-Benefit Analysis Dexamethasone Double-Blind Method Drug Administration Schedule Drug Costs Glucocorticoids Hematoma Subdural Chronic Humans Multicenter Studies as Topic Randomized Controlled Trials as Topic Time Factors Treatment Outcome United Kingdom
Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23.
Dorota Jamrozy, Merijn W Bijlsma, Marcus C de Goffau, Diederik van de Beek, Taco W Kuijpers, Julian Parkhill, Arie van der Ende, Stephen D Bentley
Aug 03, 2020
Group B streptococcus (GBS) is the leading cause of neonatal invasive disease worldwide. In the Netherlands incidence of the disease increased despite implementation of preventive guidelines. We describe a genomic analysis of...
Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23
Dorota Jamrozy, Merijn W. Bijlsma, Marcus C. de Goffau, Diederik van de Beek, Taco W. Kuijpers, Julian Parkhill, Arie van der Ende, Stephen D. Bentley
Jun 12, 2020
Abstract: Group B streptococcus (GBS) is the leading cause of neonatal invasive disease worldwide. In the Netherlands incidence of the disease increased despite implementation of preventive guidelines. We describe a genomic...
Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients
Ernest van Veen, Mathieu van der Jagt, Giuseppe Citerio, Nino Stocchetti, Diederik Gommers, Alex Burdorf, David K Menon, Andrew IR Maas, Erwin JO Kompanje, Hester F Lingsma, CENTER-TBI Investigators and Participants
Nov 05, 2021
BACKGROUND: In patients with severe brain injury, withdrawal of life-sustaining measures (WLSM) is common in intensive care units (ICU). WLSM constitutes a dilemma: instituting WLSM too early could result in death despite the...
Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma
Ellie Edlmann, Eric P Thelin, Karen Caldwell, Carole Turner, Peter Whitfield, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A Anderson, Oliver Richards, Monica Gherle, Emma Toman, Dipankar Nandi, Phillip Kane, Beatrice Pantaleo, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J Marcus, Aswin Chari, Antonio Belli, Simon Bond, Rafael Gafoor, Sarah Dawson, Lynne Whitehead, Paul Brennan, Ian Wilkinson, Angelos G Kolias, Peter JA Hutchinson, Dex-CSDH trial collaborative and BNTRC collaborative.
Mar 08, 2019
Structured light enables biomimetic swimming and versatile locomotion of photoresponsive soft microrobots.
Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury
Peter J Hutchinson, Angelos G Kolias, Tamara Tajsic, Amos Adeleye, Abenezer Tirsit Aklilu, Tedy Apriawan, Abdul Hafid Bajamal, Ernest J Barthélemy, B Indira Devi, Dhananjaya Bhat, Diederik Bulters, Randall Chesnut, Giuseppe Citerio, D Jamie Cooper, Marek Czosnyka, Idara Edem, Nasser MF El-Ghandour, Anthony Figaji, Kostas N Fountas, Clare Gallagher, Gregory WJ Hawryluk, Corrado Iaccarino, Mathew Joseph, Tariq Khan, Tsegazeab Laeke, Oleg Levchenko, Baiyun Liu, Weiming Liu, Andrew Maas, Geoffrey T Manley, Paul Manson, Anna T Mazzeo, David K Menon, Daniel B Michael, Susanne Muehlschlegel, David O Okonkwo, Kee B Park, Jeffrey V Rosenfeld, Gail Rosseau, Andres M Rubiano, Hamisi K Shabani, Nino Stocchetti, Shelly D Timmons, Ivan Timofeev, Chris Uff, Jamie S Ullman, Alex Valadka, Vicknes Waran, Adam Wells, Mark H Wilson, Franco Servadei
May 07, 2019
Management of Mild Traumatic Brain Injury at the Emergency Department and Hospital Admission in Europe
Kelly A Foks, Maryse C Cnossen, Diederik WJ Dippel, Andrew IR Maas, David Menon, Joukje van der Naalt, Ewout W Steyerberg, Hester F Lingsma, Suzanne Polinder
Nov 19, 2018
Previous studies have indicated that there is no consensus about management of mild traumatic brain injury (mTBI) at the emergency department (ED) and during hospital admission. We aim to study variability between management...
Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23
Dorota Jamrozy, Merijn W. Bijlsma, Marcus C. de Goffau, Diederik van de Beek, Taco W. Kuijpers, Julian Parkhill, Arie van der Ende, Stephen D. Bentley
Jun 12, 2021
Abstract: Group B streptococcus (GBS) is the leading cause of neonatal invasive disease worldwide. In the Netherlands incidence of the disease increased despite implementation of preventive guidelines. We describe a genomic...
Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis.
John A Lees, Philip HC Kremer, Ana S Manso, Nicholas J Croucher, Bart Ferwerda, Mercedes Valls Serón, Marco R Oggioni, Julian Parkhill, Matthijs C Brouwer, Arie van der Ende, Diederik van de Beek, Stephen D Bentley
Sep 06, 2019
Recent studies have provided evidence for rapid pathogen genome diversification, some of which could potentially affect the course of disease. We have previously described such variation seen between isolates infecting the blood...
Neisseria meningitidis Streptococcus pneumoniae ivr locus Meningitis pan-genome calling within-host evolution Adaptation Biological Blood-Brain Barrier Carrier State DNA Bacterial genetic variation Humans Meningitis Meningococcal Meningitis Pneumococcal nasopharynx Neisseria meningitidis Streptococcus pneumoniae whole genome sequencing
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting.
Tesa M Severson, Denise M Wolf, Christina Yau, Justine Peeters, Diederik Wehkam, Philip C Schouten, Suet-Feung Chin, Ian J Majewski, Magali Michaut, Astrid Bosma, Bernard Pereira, Tycho Bismeijer, Lodewyk Wessels, Carlos Caldas, René Bernards, Iris M Simon, Annuska M Glas, Sabine Linn, Laura van 't Veer
Dec 13, 2017
Humans Breast Neoplasms BRCA1 Protein Antineoplastic Combined Chemotherapy Protocols Treatment Outcome Chemotherapy Adjuvant Neoadjuvant Therapy Cluster Analysis Sensitivity and Specificity Gene Expression Profiling Gene Expression Regulation Neoplastic Female Gene Regulatory Networks Triple Negative Breast Neoplasms Biomarkers Tumor Poly(ADP-ribose) Polymerase Inhibitors
Published by: Breast cancer research : BCR
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