Search
Results: 2226
Direitos Sociais na Constituição Uma Análise da Constitucionalização dos Direitos Sociais em Portugal, 1975-76
Embora todas as constituições incluam direitos, e muitas delas incluam direitos sociais, a verdade é que algumas são mais generosas do que outras a este respeito. Mas nenhuma se aproxima da Constituição da República Portuguesa...
Scholarship Endowment Commemorates Late Alumna Lin Fearrington Thomas '81, '83
Winthrop University
Jan 01, 0001
Recent endowment has made the Lin Fearrington Thomas Scholarship a permanent fund at Winthrop. Thomas earned B.A. and M.B.A. degrees as a post-traditional student in the 1980s.
Published by: Winthrop University
A Hybrid Binary Bird Swarm Optimization (BSO) and Dragonfly Algorithm (DA) for VM Allocation and Load Balancing in Cloud
The cloud platform is becoming one of the fastest-rising environments in human activities, connecting the whole world in the upcoming decades. The three crucial aspects of cloud computing that enhance the quality of service are...
Published by: IGI Global Scientific Publishing
Giovanni Canestrini’s models of Leonardo da Vinci’s friction experiments
IM Hutchings
Feb 16, 2017
Among the exhibits at the 2016 Leonardo da Vinci exhibition at the Science Museum, London, was one that purported to illustrate Leonardo’s experiments on friction. The models involved were the work of Giovanni Canestrini...
Program for the Stage Production of Two One-Act Plays: She Was Only a Farmer's Daughter & Aria Da Capo
Curtain Club
Jan 01, 0001
This two-page program details the Curtain Club of Ursinus College's production of two one-act plays, "She Was Only a Farmer's Daughter" and "Aria Da Capo", held March 19, 1966. It includes information about the casting and...
She Was Only a Farmer's Daughter Aria Da Capo Millard Crosby Edna St. Vincent Millay Curtain Club Ursinus College theater program Theatre and Performance Studies Theatre History
Published by: Ursinus College
Monitoring ash dieback (Hymenoscyphus fraxineus) in British forests using hyperspectral remote sensing
Abstract: Large‐scale dieback of ash trees (Fraxinus spp.) caused by the fungus Hymenoscyphus fraxineus is posing an immense threat to forest health in Europe, requiring effective monitoring at large scales. In this study, a...
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
DREAM represses distinct targets by cooperating with different THAP domain proteins.
Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Yan Dong, Jane Murphy, Andrea Frapporti, Julie Ahringer
Sep 27, 2021
The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two...
dream H2A.Z H3K9me2 THAP lin-15B lin-35 lin-36 quiescence retinoblastoma TRANSCRIPTIONAL REPRESSION Animals Animals Genetically Modified Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Proteins DNA Methylation E2F Transcription Factors Gene Expression Regulation Histones Promoter Regions Genetic Protein Binding Protein Interaction Domains and Motifs Retinoblastoma Protein Transcription Factors
A protein complex required for polar growth of rhizobial infection threads
Cheng-Wu Liu, Andrew Breakspear, Nicola Stacey, Kim Findlay, Jin Nakashima, Karunakaran Ramakrishnan, Miaoxia Liu, Fang Xie, Gabriella Endre, Fernanda de Carvalho-Niebel, Giles E. D. Oldroyd, Michael K. Udvardi, Joëlle Fournier, Jeremy D. Murray
Jun 27, 2020
Abstract: During root nodule symbiosis, intracellular accommodation of rhizobia by legumes is a prerequisite for nitrogen fixation. For many legumes, rhizobial colonization initiates in root hairs through transcellular infection...
Genetic and environmental risk factors for atherosclerosis regulate transcription of phosphatase and actin regulating gene PHACTR1.
Michael E Reschen, Da Lin, Anil Chalisey, Elizabeth J Soilleux, Christopher A O'Callaghan
Dec 17, 2018
BACKGROUND AND AIMS: Coronary artery disease (CAD) risk is associated with non-coding genetic variants at the phosphatase and actin regulating protein 1(PHACTR1) gene locus. The PHACTR1 gene encodes an actin-binding protein with...
Atherosclerosis Expression quantitative trait locus (eQTL) Functional genomics genetic disease Genetic polymorphism Genomics Low-density lipoprotein (LDL) Myocardial Infarction Oxidized low density lipoprotein (oxLDL) PHACTR1 Adult Aged Alleles Atherosclerosis Coronary Artery Disease Coronary Vessels Endothelial Cells Gene Expression Regulation Gene-Environment Interaction Genotype Humans Inflammation Lipopolysaccharides MACROPHAGES Microfilament Proteins Middle Aged Muscle Smooth Vascular Polymorphism Single Nucleotide Tumor Necrosis Factor-alpha Young Adult
The Shift from Energy to Water Limitation in Local Canopy Height from Temperate to Tropical Forests in China
Canopy height greatly affects the biomass stock, carbon dynamics, and maintenance of biodiversity in forests. Previous research reported that the maximum forest canopy height (Hmax) at global and regional scales could be...
B Wang, S Fang, Y Wang, Q Guo, T Hu, X Mi, L Lin, G Jin, DA Coomes, Z Yuan, J Ye, X Wang, F Lin, Z Hao
Apr 24, 2022
Extracellular Matrix Biomimetic Hydrogels, Encapsulated with Stromal Cell-Derived Factor 1, Improve the Composition of Foetal Tissue Grafts in a Rodent Model of Parkinson's Disease.
Vanessa Penna, Niamh Moriarty, Yi Wang, Kevin CL Law, Carlos W Gantner, Richard J Williams, David R Nisbet, Clare L Parish
Apr 25, 2022
Clinical studies have provided evidence for dopamine (DA) cell replacement therapy in Parkinson's Disease. However, grafts derived from foetal tissue or pluripotent stem cells (PSCs) remain heterogeneous, with a high proportion...
Parkinson’s disease SDF1 biomaterials Dopamine Hydrogel Laminin self-assembling peptide Stem Cells stromal cell-derived factor 1 Transplantation Animals Biomimetics Cell Differentiation Chemokine CXCL12 Dopamine Dopaminergic Neurons Extracellular Matrix Fetus Hydrogels Laminin Parkinson Disease Rodentia
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
Apr 02, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
May 15, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
Animals Basement Membrane Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Checkpoints Cell Differentiation Cell Proliferation G1 Phase Cell Cycle Checkpoints Gene Expression MDS1 and EVI1 Complex Locus Protein Proto-Oncogene Mas Proto-Oncogene Proteins c-fos Proto-Oncogenes Receptors Notch Signal Transduction Transcription Factors
Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.
Reinhard Roessler, Sebastien A Smallwood, Jesse V Veenvliet, Petros Pechlivanoglou, Su-Ping Peng, Koushik Chakrabarty, Marian JA Groot-Koerkamp, R Jeroen Pasterkamp, Evelyn Wesseling, Gavin Kelsey, Erik Boddeke, Marten P Smidt, Sjef Copray
Jun 24, 2019
Induced pluripotent stem cells (iPSCs) hold great promise for in vitro generation of disease-relevant cell types, such as mesodiencephalic dopaminergic (mdDA) neurons involved in Parkinson's disease. Although iPSC-derived...
The immunogenicity of midbrain dopaminergic neurons and the implications for neural grafting trials in Parkinson's disease.
Dopaminergic (DA) cell replacement therapies are a promising experimental treatment for Parkinson's disease (PD) and a number of different types of DA cell-based therapies have already been trialled in patients. To date, the...
A novel deep intronic variant strongly associates with Alkaptonuria.
Chien-Yi Lai, I-Jung Tsai, Pao-Chin Chiu, David B Ascher, Yin-Hsiu Chien, Yu-Hsuan Huang, Yi-Lin Lin, Wuh-Liang Hwu, Ni-Chung Lee
Oct 22, 2021
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
Nitrous oxide emissions from sugarcane fields in the Brazilian Cerrado
J Fonseca da Silva, A Moreira de Carvalho, TA Rein, T Rodrigues Coser, W Quadros Ribeiro, D Lino Vieira, DA Coomes
Nov 24, 2017
Brazil meets about 16% of its energy needs with bioethanol and other sugarcane products and leads the world in biofuel energy production. However, there are concerns over the environmental credentials of the sugarcane given the...
Text Chat-Mediated Dynamic Assessment Towards Self-Regulation in Language Learning
Even though the importance of corrective feedback (CF) is widely recognized, there is no agreement on the most effective type of CF for promoting self-regulation. Thus, this study adopts a sociocultural perspective on learning...
Published by: IGI Global Scientific Publishing
Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.
Michael E Reschen, Kyle J Gaulton, Da Lin, Elizabeth J Soilleux, Andrew J Morris, Susan S Smyth, Christopher A O'Callaghan
Dec 17, 2018
Genome-wide association studies (GWAS) have identified over 40 loci that affect risk of coronary artery disease (CAD) and the causal mechanisms at the majority of loci are unknown. Recent studies have suggested that many causal...
|
|< |
< |
1 |